Results 11 to 20 of about 30,729 (226)
Pharmaceutics, 2017 The potential of inhibitory metabolites of perpetrator drugs to contribute to drug-drug interactions (DDIs) is uncommon and underestimated. However, the occurrence of unexpected DDI suggests the potential contribution of metabolites to the observed DDI ...
Caifu Xue, Xunjie Zhang, Weimin Cai
doaj +2 more sources
Is There a Potential of Misuse for Venlafaxine and Bupropion?
Frontiers in Pharmacology, 2018 Objective: Traditionally, studies on the non-medical use of pharmaceutical products have focused on controlled substances; e.g., opiates/opioids; and benzodiazepines.
Fabrizio Schifano, Stefania Chiappini
doaj +2 more sources
Frontiers in Psychiatry, 2018 Background: Previous research indicates that antidepressants can restore the balance between negative and positive emotional processing early in treatment, indicating a role of this effect in later mood improvement.
Annabel E. L. Walsh +9 more
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Successful use of ECMO and lipid emulsion for massive bupropion overdose: a case report
Toxicology Communications, 2021 Introduction Bupropion overdose can produce seizures, arrhythmias, and shock. The toxicokinetics of massive bupropion ingestions are not well characterized.Case report A 22-year-old female ingested an estimated 40.5 g (644 mg/kg) of extended release ...
Michael E. O’Brien +5 more
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Dextromethorphan-bupropion (Auvelity) for the Treatment of Major Depressive Disorder
Clinical Psychopharmacology and Neuroscience, 2023 Depression is a significant cause of morbidity and mortality globally. Although various pharmacologic options exist for depression, treatments are limited by delayed or incomplete therapeutic response, low rates of remission, and adverse effects ...
B. McCarthy +5 more
semanticscholar +1 more source
Adsorption of Bupropion on C60 Nanocage: Thermodynamic and Electronic Properties [PDF]
Nanochemistry Research, 2022 Bupropion is a drug primarily used for treating major depressive disorder and helping smokers quit smoking. Bupropion is a fairly effective antidepressant, but it leads to restlessness and palpitations at relatively high doses. In addition, it is used as
Zhila NazarAli +3 more
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Bupropion and Naltrexone in Methamphetamine Use Disorder
New England Journal of Medicine, 2021 BACKGROUND The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied. METHODS We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison ...
M. Trivedi +19 more
semanticscholar +1 more source
Journal of Clinical Psychiatry, 2022 Objective: Altered glutamatergic neurotransmission has been implicated in the pathogenesis of depression. This trial evaluated the efficacy and safety of AXS-05 (dextromethorphan-bupropion), an oral N-methyl-D-aspartate (NMDA) receptor antagonist and σ1 ...
D. Iosifescu +6 more
semanticscholar +1 more source
Naltrexone/Bupropion for Binge-Eating Disorder: A Randomized Double-Blind Placebo-Controlled Trial
Obesity, 2023 Binge‐eating disorder (BED) is a prevalent psychiatric disorder associated with obesity. Few evidence‐based treatments exist for BED, particularly pharmacological options. This study tested the efficacy of naltrexone/bupropion for BED.
C. Grilo +4 more
semanticscholar +1 more source
Health Psychology Research, 2023 Bupropion had been in use since the late 1980s as an unconventional treatment for depression. Unlike other antidepressants, bupropion has no serotonergic activity and inhibits the reuptake of norepinephrine and dopamine.
Alan L. Clark +9 more
semanticscholar +1 more source