Results 21 to 30 of about 37,026 (217)
Diabetes, Metabolic Syndrome and Obesity, 2022 Sarah Dahlberg,1 Ellen T Chang,1 Sheila R Weiss,1 Pamela Dopart,1 Errol Gould,2 Mary E Ritchey3 1Exponent, Inc, Menlo Park, CA, 94025, USA; 2Currax Pharmaceuticals LLC., Brentwood, TN, 37027, USA; 3Med Tech Epi, LLC., Philadelphia, PA, 19147 ...
Dahlberg S +5 more
doaj
Sakarya Tıp Dergisi, 2018 Bu çalışmada, farelerde desipramin, venlafaksin ve bupropiyonun depresyon ve anksiyete üzerine etkilerini araştırmayı amaçladık. Klasik trisiklik antidepresan, desipramin, serotonin-norepinefrin geri alım inhibitörü venlafaksin ve ikinci jenerasyon ...
Mehmet Emin Büyükokuroğlu +6 more
doaj +1 more source
Drugs in R&D, 2010 In March 2010, Orexigen(R) Therapeutics submitted a new drug application (NDA) for approval of naltrexone sustained release (SR)/bupropion SR (Contrave(R)) for the treatment of obesity in the US. The tablet contains naltrexone SR 32 mg and bupropion SR 360 mg.
openaire +2 more sources
Enhanced neural response to anticipation, effort and consummation of reward and aversion during Bupropion treatment [PDF]
, 2016 Background We have previously shown that the selective serotonergic re-uptake inhibitor, citalopram, reduces the neural response to reward and aversion in healthy volunteers. We suggest that this inhibitory effect might underlie the emotional blunting
C. McCabe +5 more
core +1 more source
Pharmaceutics, 2017 The potential of inhibitory metabolites of perpetrator drugs to contribute to drug-drug interactions (DDIs) is uncommon and underestimated. However, the occurrence of unexpected DDI suggests the potential contribution of metabolites to the observed DDI ...
Caifu Xue, Xunjie Zhang, Weimin Cai
doaj +1 more source
Peptic Ulcer Disease Following Use of Bupropion: A Case Report
Clinical Medicine Insights: Case Reports, 2023 Background: Bupropion is a dopamine reuptake inhibitor, which is prescribed as an effective drug for the treatment of depression and as a complementary drug for smoking cessation in more than 50 countries.
Zahra Momayez Sanat +2 more
doaj +1 more source
Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core +1 more source
Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS [PDF]
, 2016 Bupropion metabolites formed via oxidation and reduction exhibit pharmacological activity, but little is known regarding their stereoselective disposition.
Desta, Zeruesenay +3 more
core +1 more source
Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg depression rating scale, the gold standard clinician rating scale : a meta-analysis of randomised placebo-controlled trials [PDF]
, 2020 It has been claimed that efficacy estimates based on the Hamilton Depression Rating-Scale (HDRS) underestimate antidepressants true treatment effects due to the instrument's poor psychometric properties.
Hengartner, Michael Pascal +3 more
core +2 more sources
Bupropion perceived as a stimulant by two patients with a previous history of cocaine misuse
Annali dell'Istituto Superiore di Sanità, 2013 BACKGROUND AND OBJECTIVE: Despite animal studies having shown a generalisation of the bupropion cue to cocaine, this drug has been used in cocaine abuse with mixed results. We here aimed at describing two cases which contradict current knowledge.
Alessandro E. Vento +6 more
doaj +1 more source