Results 51 to 60 of about 37,508 (242)

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents

Neuropsychiatric Disease and Treatment, 2009
David C Henshall1, Nick Dürmüller2, H Steve White3, Robert Williams4, Paul Moser2, Mark Dunleavy1, Peter H Silverstone51Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland; 2Porsolt and ...
David C Henshall, Nick Dürmüller, H Steve White, Robert Williams, et al.   +3 more
doaj  

A fatal case of bupropion (Zyban) hepatotoxicity with autoimmune features: Case report

Journal of Medical Case Reports, 2007
Background Bupropion is approved for the treatment of mood disorders and as an adjuvant medication for smoking cessation. Bupropion is generally well tolerated and considered safe.
Humayun Fawwaz, Shehab Thomas M, Tworek Joseph A, Fontana Robert J   +3 more
doaj   +1 more source

Generalized tonic-clonic seizure induced by the extended- release bupropion hydrochloride formulation

Psychiatry and Clinical Psychopharmacology, 2021
Bupropion hydrochloride (HCl) is currently available in three formulations: immediate-release (IR), sustained-release (SR), and extended-release (ER). bupropion HCl immediaterelease and sustained- release formulations have been known to trigger seizure ...
Erhan Dedeoğlu, Başak Bayram, Ali Ufuk Kızıler, Berrin Dedeoğlu   +3 more
doaj   +1 more source

Recent Changes in Drug Abuse Scenario: The Novel Psychoactive Substances (NPS) Phenomenon [PDF]

, 2019
copyright 2019 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are ...
Catalani, Valeria, Chilcott, Robert, Corazza, Ornella, Corkery, John, Guirguis, Amira, Marrinan, Shanna, Martinotti, Giovanni, Zloh, Mire   +7 more
core   +3 more sources

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner, Franziska Eberhardt, Manuela Kofler, Andreas Eigentler, Atbin Djamshidian, Florian Krismer, Anton Hittmair, Heinz Zoller, Valentina Ellinger, Beatrice Heim, Klaus Seppi   +10 more
wiley   +1 more source

Bupropion use and risk of open-angle glaucoma among enrollees in a large U.S. managed care network. [PDF]

PLoS ONE, 2015
Tumor Necrosis Factor (TNF) mediates retinal ganglion cell death in glaucoma. Anti-TNF drugs are neuroprotective in an animal model of glaucoma. It is unclear whether medications with anti-TNF properties such as bupropion have an impact on the risk of ...
Joshua D Stein, Nidhi Talwar, Jae H Kang, Olivia I Okereke, Janey L Wiggs, Louis R Pasquale   +5 more
doaj   +1 more source

Twenty‐Four Month Outcomes From a Real‐World Telehealth Obesity Treatment Clinic Using Obesity Medications

Obesity, EarlyView.
ABSTRACT Objective Antiobesity medications (AOMs) are indicated for long‐term use; however, evidence of their real‐world long‐term efficacy is limited. This study describes clinical outcomes from 18‐ and 24‐month use of AOMs in a telemedicine weight management clinic.
Kathleen R. Ruddiman, Young‐Rock Hong, Jamy Ard, Rebecca Jones, Adam Medcalf, Gary D. Foster, Jamil Alkhaddo, Michelle Cardel   +7 more
wiley   +1 more source

Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS [PDF]

, 2016
Bupropion metabolites formed via oxidation and reduction exhibit pharmacological activity, but little is known regarding their stereoselective disposition.
Desta, Zeruesenay, Jones, David R., McCoy, Michael, Masters, Andrea R.   +3 more
core   +1 more source

Prevalence of Pre‐Clinical Obesity Among US Adults Receiving Medical and Surgical Obesity Treatment

Obesity, EarlyView.
ABSTRACT Objective We sought to determine how the proportion of adults historically receiving obesity interventions would be classified under the recently proposed “pre‐clinical” and “clinical” obesity classifications and the impact of this change on safety and outcomes.
Jason M. Samuels, Emma Holler, Matthew D. Spann, C. Joe Northup, Tarik K. Yuce   +4 more
wiley   +1 more source