Results 111 to 120 of about 3,444,641 (410)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

open access: yesLancet Neurology
Summary Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19.
Jaimie D Steinmetz   +499 more
semanticscholar   +1 more source

Burden, depression, and anxiety in caregivers of people with amyotrophic lateral sclerosis

open access: yes, 2010
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease caused by the degeneration of motor neurons. The burden for ALS caregivers is quite high.
Castelnuovo, Gianluca   +2 more
core   +1 more source

The burden of disease profile of residents of Nairobi's slums: results from a demographic surveillance system. [PDF]

open access: yes, 2008
BACKGROUND: With increasing urbanization in sub-Saharan Africa and poor economic performance, the growth of slums is unavoidable. About 71% of urban residents in Kenya live in slums. Slums are characteristically unplanned, underserved by social services,
Kyobutungi, Catherine   +11 more
core   +1 more source

Introduction to the Mountain Caribou in Managed Forests Program

open access: yesRangifer, 1996
Short introduction to a group of papers with focus on the woodland caribou in eastern British Columbia.
Susan K. Stevenson
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Prevention of caregiver's Burden in chronic-degenerative disease

open access: yes, 2022
reservedPROBLEMA: Con il termine burden del caregiver si intende una particolare risposta allo stress cronico che viene percepito dai caregiver e dovuto alle loro azioni di cura nei confronti di familiari ammalati. Il burden del caregiver è una sindrome
VIALE, DAVÌ
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

open access: yesLancet Neurology, 2019
Summary Background The number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world.
Emma Cassandra E I Stein Emil Nooshin Foad Jemal Miloud Nichols Szoeke Vollset Abbasi Abd-Allah Abdela Aic   +146 more
semanticscholar   +1 more source

Cost‐effectiveness of asthma clinic approach in the management of chronic asthma in Australia

open access: yesAustralian and New Zealand Journal of Public Health, 2013
Objectives: To compare cost‐effectiveness of an asthma clinic that would provide education, promotion of self‐monitoring of symptoms, regular review of treatment by a medical practitioner and a written asthma action plan to current practice in Australia.
Vittal Mogasale, Theo Vos
doaj   +1 more source

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