Results 131 to 140 of about 3,444,641 (410)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Doorway to Heaven

, 1973
At 6 p.m. I stood in the doorway of my studio facing the Venice boardwalk. A few spectators watched as I pushed two live electric wires into my chest. The wires crossed and exploded, burning me but saving me from electrocution.full view, wires crossed ...
Burden, Chris
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Lancet Neurology, 2017
Summary Background Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most ...
V. Feigin, A. Abajobir, K. H. Abate, F. Abd-Allah, A. Abdulle, S. Abera, G. Abyu, M. Ahmed, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, R. Akinyemi, S. Alabed, R. Al-Raddadi, N. Alvis-Guzmán, A. Amare, H. Ansari, P. Anwari, J. Ärnlöv, H. Asayesh, S. W. Asgedom, T. Atey, L. Ávila-Burgos, Euripide Frinel, G. A. Avokpaho, M. Azarpazhooh, A. Barać, M. Barboza, S. Barker-Collo, T. Bärnighausen, Neeraj Bedi, E. Beghi, D. Bennett, I. Benseñor, A. Berhane, B. Betsu, S. Bhaumik, Sait Mentes Birlik, S. Biryukov, D. Boneya, L. Bulto, H. Carabin, Daniel C. Casey, C. Castañeda-Orjuela, F. Catalá-López, Honglei Chen, Abdulaal Chitheer, Rajiv Chowdhury, H. Christensen, L. Dandona, R. Dandona, G. Veber, S. Dharmaratne, H. Do, K. Dokova, E. Dorsey, R. Ellenbogen, S. Eskandarieh, M. Farvid, S. Fereshtehnejad, F. Fischer, Kyle Foreman, J. Geleijnse, R. Gillum, G. Giussani, Ellen M. Goldberg, P. Gona, A. Goulart, H. Gugnani, Rahul Gupta, V. Hachinski, R. Gupta, R. Hamadeh, M. Hambisa, G. Hankey, H. Hareri, Rasmus J. Havmoeller, Simon Iain Hay, P. Heydarpour, P. Hotez, M. Jakovljevic, Mehdi Javanbakht, P. Jeemon, J. Jonas, Yogeshwar V. Kalkonde, A. Kandel, A. Karch, A. Kasaeian, A. Kastor, P. Keiyoro, Y. Khader, I. Khalil, E. Khan, Y. Khang, Abdullah Tawfih, A. Khoja, J. Khubchandani, Chanda Kulkarni, Daniel H. Kim, Y. Kim, M. Kivimäki, Y. Kokubo, S. Kosen, M. Kravchenko, R. Krishnamurthi, B. K. Defo, G. Kumar, Rashmi Kumar, H. Kyu, A. Larsson, P. Lavados, Yongmei Li, Xiaofeng Liang, Misgan Legesse Liben, W. Lo, G. Logroscino, P. Lotufo, C. Loy, M. Mackay, H. A. E. Razek, M. Razek, A. Majeed, R. Malekzadeh, Treh Manhertz, L. Mantovani, J. Massano, M. Mazidi, C. McAlinden, S. Mehata, M. Mehndiratta, Ziad A. Memish, W. Mendoza, Mubarek Abera Mengistie, G. Mensah, A. Meretoja, H. Mezgebe, Ted R. Miller, S. Mishra, N. Ibrahim, A. Mohammadi, Kedir Mohammed Oumer, S. Mohammed, A. Mokdad, M. Moradi-Lakeh, I. M. Velásquez, K. Musa, M. Naghavi, J. Ngunjiri, Cuong Tat Nguyen, Grant Nguyen, Q. Nguyen, T. Nguyen, Emma Nichols, D. N. A. Ningrum, V. M. Nong, B. Norrving, J. Noubiap, F. Ogbo, M. Owolabi, J. Pandian, P. Parmar, David M Pereira, Max Petzold, M. Phillips, M. Piradov, R. Poulton, F. Pourmalek, M. Qorbani, Anwar Rafay, Mahfuzar Rahman, Mohammad Hifz Ur Rahman, R. Rai, Sasa Rajsic, Annemarei Ranta, S. Rawaf, Andre M. N. Renzaho, M. S. Rezai, Gregory A. Roth, G. Roshandel, Enrico Rubagotti, P. Sachdev, Saeid Safiri, R. Sahathevan, M. Sahraian, A. Samy, Paula Santalucia, I. Santos, B. Sartorius, Maheswar Satpathy, M. Sawhney, M. Saylan, S. Sepanlou, M. Shaikh, R. Shakir, M. Shamsizadeh, K. Sheth, M. Shigematsu, Haitham Shoman, D. Silva, Mari Smith, E. Sobngwi, L. Sposato, J. Stanaway, D. Stein, T. Steiner, L. Stovner, R. Abdulkader, C. Szoeke, R. Tabarés-Seisdedos, D. Tanné, A. Theadom, A. Thrift, D. Tirschwell, R. Topor-Madry, B. Tran, T. Truelsen, K. Tuem, K. Ukwaja, O. Uthman, Yuri Y Varakin, T. Vasankari, N. Venketasubramanian, V. Vlassov, F. Wadilo, Tolassa Wakayo, M. Wallin, E. Weiderpass, R. Westerman, T. Wijeratne, C. Wiysonge, M. Woldu, C. Wolfe, D. Xavier, Gelin Xu, Y. Yano, H. H. Yimam, N. Yonemoto, Chuanhua Yu, Z. Zaidi, M. Zaki, J. Zunt, C. Murray, T. Vos   +242 more
semanticscholar   +1 more source

New Methodology for Estimating the Burden of Infectious Diseases in Europe [PDF]

, 2012
Kretzschmar M, Mangen M-JEJ, Pinheiro JP, et al. New Methodology for Estimating the Burden of Infectious Diseases in Europe. PLoS Medicine.
consortium, BCoDE, Fevre, Eric M., Lai Taavi, Claudia Stein, Mangen, MJ, Dep IRAS, FRANCO, ELISABETTA, Fevre, E.M., Kretzschmar, Mirjam, BCoDE consortium, Piotr Kramarz, Havelaar Arie H., Stein Claudia, Mangen, M, Pinheiro, P, Paulo Pinheiro, Beate Jahn, Mangen Marie-Josée J., Havelaar, AH, Cassini, Alessandro, Fèvre Eric M., Havelaar, A, Pinheiro, Paulo, Fevre, Eric, Longhi, Silvia, Havelaar, Arie H, Lai, Taavi, Fèvre, Eric M, Stein, C, Mangen, Marie-Josée J, Longhi, S, Beate Jahn (170765), Mirjam Kretzschmar, Mirjam Kretzschmar (27309), ?, ?, Longhi Silvia, Fèvre, EM, Mangen, M.J.J., Stein, C., Mangen, Marie-Josee E. J., Stein, C,, Cassini Alessandro, Eric M. Fèvre (125784), Pinheiro, Joao Paulo, Mangen, M.J., Pinheiro Paulo, Arie H. Havelaar (170779), Alessandro Cassini (170788), Risk Assessment of Toxic and Immunomodulatory Agents, Taavi Lai, Havelaar, A.H., Kramarz, Piotr, Arie H Havelaar, Kretzschmar Mirjam, Jahn, B., Cassini, A., BCoDE consortium, x, Lai, T, Kramarz, P, Piotr Kramarz (170792), Stein, Claudia, Kramarz Piotr, Jahn, Beate, Fèvre, E, Cassini, A, Marie-Josée J Mangen, Marie-Josée J. Mangen (170760), Havelaar, Arie H., Kretzschmar, M.E.E., Pinheiro, P., Silvia Longhi (170771), Jahn, B, Eric M Fèvre, Ricciardi, Gualtiero, Kretzschmar, M., Paulo Pinheiro (170764), Jahn Beate, Franco, E, Lai, T., Kramarz, P., Alessandro Cassini, Longhi, S., Taavi Lai (170775), Claudia Stein (170785), Silvia Longhi, Kretzschmar, M   +85 more
core   +1 more source

Tracking poison ingestion deaths for South Africa: The need for access to timely reliable data

South African Medical Journal
The President of South Africa addressed the nation on 15 November 2024 regarding the rise in food-borne illnesses and related child deaths. In the absence of a clear profile of injury deaths from official cause-of-death data, we used empirical ...
M Prinsloo, R A Roomaney, I Neethling, N W Basera, P Groenewald, R Matzopoulos, D Bradshaw   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Lancet Neurology
Summary Background Up-to-date estimates of stroke burden and attributable risks and their trends at global, regional, and national levels are essential for evidence-based health care, prevention, and resource allocation planning. We aimed to provide such
Valery L. Feigin, Melsew Dagne Abate, Y. Abate, S. ElHafeez, F. Abd-Allah, A. Abdelalim, A. Abdelkader, Michael Abdelmasseh, S. Abd-Elsalam, P. Abdi, Arash Abdollahi, M. Abdoun, R. Abd-Rabu, Deldar Morad Abdulah, Auwal Abdullahi, Mesfin Abebe, Roberto Ariel Abeldaño Zuñiga, E. Abhilash, O. Abiodun, O. Abiodun, R. Kasem, R. Aboagye, M. Abouzid, Lucas Guimarães Abreu, Woldu Aberhe Abrha, Dariush Abtahi, Samir Abu Rumeileh, Ahmed Abualhasan, Hasan Abualruz, Eman Abu-Gharbieh, Hana J. Abukhadijah, N. Abu-Rmeileh, Salahdein Aburuz, Ahmed Abu-Zaid, J. M. Acuna, Denberu Eshetie Adane, M. M. Adane, Isaac Yeboah Addo, R. Adedoyin, O. Adegboye, Victor Adekanmbi, Kishor Adhikari, Q. Adnani, Saryia Adra, Leticia Akua Adzigbli, A. Afify, A. Afolabi, Fatemeh Afrashteh, M. Afzal, Saira Afzal, Shahin Aghamiri, Williams Agyemang-Duah, B. Ahinkorah, Aqeel Ahmad, Muayyad M. Ahmad, Sajjad Ahmad, Shahzaib Ahmad, Tauseef Ahmad, A. M. Ahmadzade, Ali Ahmed, Ayman Ahmed, H. Ahmed, Syed Anees Ahmed, Marjan Ajami, Budi Aji, E. Akara, R. Akinyemi, M. Akkaif, Ashley E Akrami, S. Awaidy, H. A. Hamad, S. M. Hasan, M. Qadire, O. Ta'ani, Yazan A. Al-Ajlouni, Samer O. Alalalmeh, T. Alalwan, Z. Al-Aly, Rasmieh M. Al-amer, W. Aldhaleei, M. Aldossary, Seyedeh Yasaman Alemohammad, B. Al-Fatly, A. Al-Gheethi, F. Alhalaiqa, Maryam Alharrasi, Abid Ali, M. Ali, Rafat Ali, Syed Shujait Shujait Ali, Waad Ali, A. Al-Ibraheem, S. M. Alif, S. Aljunid, W. Almahmeed, Sabah Al-Marwani, Mahmoud A. Alomari, J. Alonso, J. Alqahtani, R. Al-Raddadi, Ahmad Alrawashdeh, Mohammed Alsabri, Najim Z. Alshahrani, Z. Altaany, Awais Altaf, Ala’a B. Al-Tammemi, Diala Altwalbeh, N. Alvis-Guzmán, Hassan Alwafi, M. Al-Wardat, Y. Al-Worafi, Hany Aly, Safwat Aly, Mohammad Sharif Ibrahim Alyahya, K. Alzoubi, W. Al-Zyoud, Reza Amani, Prince M Amegbor, Tewodros Getnet Amera, T. Amin, Alireza Amindarolzarbi, Sohrab Amiri, Hubert Amu, D. Amugsi, G. Amusa, R. Ancuceanu, D. Anderlini, Dhanalakshmi Angappan, Abhishek Anil, Mohammed Tahir Ansari, A. Ansari-Moghaddam, Rockson Ansong, Saeid Anvari, Saleha Anwar, S. Anwar, Ekenedilichukwu Emmanuel Anyabolo, A. Anyasodor, G. L. Apostol, F. Appiah, M. Aqeel, J. Arabloo, R. Bahri, M. Arafat, A. Aravkin, A. Ardekani, D. Areda, Brhane Berhe Aregawi, Getnet Mesfin Aregu, O. Aremu, Hidayat Arifin, J. Ärnlöv, A. Artamonov, Judie Arulappan, U. Aryal, Zahra Aryan, A. Asbeutah, M. Asemahagn, Mulu Tiruneh Asemu, M. Asghari-Jafarabadi, Mubarek Yesse Ashemo, Tahira Ashraf, Armin Aslani, Haftu Asmerom, T. Astell-Burt, S. Athari, P. Atorkey, M. Atout, A. Atreya, A. Aujayeb, M. Ausloos, Abolfazl Avan, Hamzeh Awad, A. Awotidebe, L. A. Ayana, S. B. Aychiluhm, A. Aynalem, Z. Aynalem, S. Azadnajafabad, H. Azami, Shahkaar Aziz, A. Azzam, Abraham Samuel Babu, G. R. Babu, Muhammad Badar, A. Badiye, Pegah Bahrami Taghanaki, Saeed Bahramian, Ruhai Bai, A. Baig, Shankar M. Bakkannavar, A. T. Bako, Ovidiu Constantin Baltatu, Kiran Bam, Maciej Banach, M. Banakar, Soham Bandyopadhyay, Palash Chandra Banik, K. Bansal, Yanping Bao, Miguel A Barboza, Mainak Bardhan, Noel C Barengo, S. Barker-Collo, T. Bärnighausen, H. Barqawi, Amadou Barrow, Lingkan Barua, A. Bashiri, H. Bashiru, A. Basiru, Mohammad-Mahdi Bastan, S. Basu, S. Basu, Kavita Batra, Ahmet Begde, Babak Behnam, A. Behnoush, Melesse Belayneh, Michael Belingheri, U. M. Bello, Derrick A. Bennett, I. Benseñor, F. T. Berhe, A. N. Bermudez, Habtamu B. Beyene, Kebede A. Beyene, D. Bhagat, A. Bhagavathula, N. Bhala, Ashish Bhalla, Nikha Bhardwaj, Pankaj Bhardwaj, Sonu M M Bhaskar, A. Bhat, Vivek Bhat, G. K. Bhatti, Jasvinder Singh Bhatti, M. Bhuiyan, S. Bhusal, B. Bikbov, C. Bilgin, Antonio Biondi, K. Bishaw, Atanu Biswas, Bijit Biswas, Trupti N. Bodhare, Eyob Ketema Bogale, A. Boloor, Milad Hashemi, A. Bonny, B. Basara, Hamed Borhany, S. Bosoka, S. Bouaoud, A. Bouyahya, Edward J. Boyko, Marija M Bozic, Dejana Braithwaite, S. Breitner, H. Brenner, Gabrielle Britton, A. Brunoni, Dana Bryazka, Raffaele Bugiardini, L. Bulto, Katrin Burkart, Yasser K. Bustanji, Z. Butt, F. C. Santos, L. Cámera, L. A. Campos, Ismael Campos-Nonato, Fan Cao, A. Capodici, Rosario Cárdenas, Sinclair Carr, G. Carreras, Andre F. Carvalho, F. Carvalho, J. Castaldelli-Maia, C. Castañeda-Orjuela, G. Castelpietra, A. Catapano, M. Cattaruzza, L. Cegolon, Francieli Cembranel, E. Cenko, Ester Cerin, J. Chadwick, Chiranjib Chakraborty, S. Chakraborty, Jeffrey Shi Kai Chan, R. Chandika, E. Chandrasekar, Gashaw Sisay Chanie, Vijay Kumar Chattu, A. Chaudhary, A. Chaurasia, Haowei Chen, Mingling Chen, Simiao Chen, Gerald Chi, Fatemeh Chichagi, Ritesh Chimoriya, Patrick R. Ching, Abdulaal Chitheer, So Mi Jemma Cho, Dong-Woo Choi, Bryan Chong, C. L. Chong, Hitesh Chopra, Sonali Gajanan Choudhari, Rahul Choudhary, D. Chu, I. Chukwu, S. Chung, Zinhle Cindi, Iolanda Cioffi, Rebecca M. Cogen, A. Columbus, S. Costanzo, Rosa A A Couto, M. Criqui, N. Cruz-Martins, Silvia Magali Cuadra-Hernández, A. Silva, Sriharsha Dadana, O. Dadras, X. Dai, K. Dalal, L. Dalli, G. Damiani, Emanuele D’Amico, L. Dandona, R. Dandona, A. Darwish, Saswati Das, M. Dashti, Mohadese Dashtkoohi, Mohammad Dashtkoohi, Maedeh Dastmardi, K. Davletov, V. D. L. Cruz-Góngora, Sean DeAngelo, Aklilu Tamire Debele, Shayom Debopadhaya, Iván Delgado-Enciso, Berecha Hundessa Demessa, A. K. Demetriades, E. Denova-Gutiérrez, Emina Dervišević, Hardik D. Desai, Aragaw Tesfaw Desale, F. Desta, Vinoth Gnana Chellaiyan Devanbu, Devananda Devegowda, Syed Masudur Rahman Dewan, A. Dhane, M. Dhimal, Vishal R Dhulipala, M. J. Diaz, Mengistie Diress, Milad Dodangeh, P. Doegah, Sushil Dohare, M. Doheim, K. Dokova, D. Dongarwar, Mario D’Oria, O. Doshi, Rajkumar Doshi, Abdel Douiri, Robert Kokou Dowou, A. C. Dsouza, H. Dsouza, V. Dsouza, Bruce B Duncan, A. Durães, Arkadiusz Marian Dziedzic, Michael Ekholuenetale, Ibrahim Farahat El Bayoumy, M. Zaki, I. Elbarazi, F. El‑Dahiyat, I. Elgendy, Muhammed Elhadi, W. El‐Huneidi, Mohamed A. Elmonem, Adel B. Elmoselhi, Chadi Eltaha, T. Emeto, C. Esezobor, Negin Esfandiari, Zahra Esmaeili, F. Esposito, Mohammad Etoom, N. Fabin, I. Fadhil, A. Fagbamigbe, O. Fagbule, S. Faghani, A. Fahim, I. Fakhradiyev, L. Falzone, Mohammad Fareed, Jawad Fares, C. Farinha, M. Faris, P. Faris, Mohsen Farjoud Kouhanjani, Andre Faro, Hossein Farrokhpour, A. Fasanmi, N. Fauk, Patrick Fazeli, Timur Fazylov, Alireza Feizkhah, G. Fekadu, Xiaoqi Feng, S. Fereshtehnejad, Pietro Ferrara, N. Ferreira, G. Fetensa, Bikila Regassa Feyisa, Florian Fischer, L. Flor, Kristen Marie Foley, Ana Catarina Fonseca, Roham Foroumadi, B. Foroutan, Daniela Fortuna, Matteo Foschi, R. Franklin, Nita Fridayani, G. Sridevi, Péter Gaál, A. Gaidhane, A. Gaipov, Yaseen Galali, S. Gallus, A. Gandhi, B. Ganesan, Danijela Gasevic, Prem Gautam, R. Gautam, M. W. Gebregergis, Mesfin Gebrehiwot, Kebre Gebrekirstos Gebrekidan, Lemma Getacher, Genanew Kassie Getahun, Molla Getie, Delaram J. Ghadimi, F. Ghadirian, Amir Ghaffari Jolfayi, M. Ghafourifard, Mohammadreza Ghasemi, Afsaneh Ghasemzadeh, R. Ghazy, Ehsan Gholami, Zainab Gholami, S. Ghozy, Stefano Giannoni Luza, J. Gilani, Tiffany K. Gill, R. F. Gillum, Ebisa Zerihun Gindaba, E. Gnedovskaya, Amit Goel, Mohamad Goldust, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, P. Gona, G. Gorini, A. Goulart, Bárbara Niegia Garcia Goulart, Mahdi Gouravani, Michale Grivna, Giuseppe Grosso, Ashna Grover, Shi-Yang Guan, G. Guarducci, Avirup Guha, S. Guicciardi, Snigdha Gulati, D. Gunawardane, Cui Guo, Zhifeng Guo, Anish Gupta, Bhawna Gupta, Mohak Gupta, Rahul Gupta, R. Gupta, R. Gupta, Sapna Gupta, Farrokh Habibzadeh, Najah R. Hadi, M. Dogahe, Hamed Haghi-Aminjan, Dariush Haghmorad   +499 more
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

The Lancet, 2018
Summary Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions.

semanticscholar   +1 more source