Results 101 to 110 of about 166,326,684 (256)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

High burden of impetigo and scabies in a tropical country. [PDF]

, 2009
BACKGROUND: Impetigo and scabies are endemic diseases in many tropical countries; however the epidemiology of these diseases is poorly understood in many areas, particularly in the Pacific.
Steer Andrew C., Batzloff, Michael R, Jenney Adam W. J., Steer, AC, Kado, Joseph, Batzloff Michael R., Mulholland, EK, Jenney, Adam WJ, Sophie La Vincente, Jonathan R Carapetis, Carapetis, JR, La Vincente, Sophie, La Vincente, S, Waqatakirewa Lepani, Waqatakirewa, L, Mulholland E. Kim, Kado, J, Carapetis, Jonathan R, Batzloff, MR, Carapetis Jonathan R., Lepani Waqatakirewa, Andrew C Steer, Waqatakirewa, Lepani, Mulholland, E Kim, Steer, Andrew C, Joseph Kado, La Vincente Sophie, Jenney, AWJ, Michael R Batzloff, E Kim Mulholland, Adam W J Jenney, Kado Joseph   +31 more
core   +2 more sources

Chris Burden 74-77

, 1978
Presentation of 31 performances by Chris Burden performed from 1974 to 1977, with notes by the ...
Burden, Chris
core   +1 more source

Perceptions about data-informed decisions: an assessment of information-use in high HIV-prevalence settings in South Africa

BMC Health Services Research, 2017
Background Information-use is an integral component of a routine health information system and essential to influence policy-making, program actions and research.
Edward Nicol, Debbie Bradshaw, Jeannine Uwimana-Nicol, Lilian Dudley   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

New Methodology for Estimating the Burden of Infectious Diseases in Europe [PDF]

, 2012
Kretzschmar M, Mangen M-JEJ, Pinheiro JP, et al. New Methodology for Estimating the Burden of Infectious Diseases in Europe. PLoS Medicine.
consortium, BCoDE, Fevre, Eric M., Lai Taavi, Claudia Stein, Mangen, MJ, Dep IRAS, FRANCO, ELISABETTA, Fevre, E.M., Kretzschmar, Mirjam, BCoDE consortium, Piotr Kramarz, Havelaar Arie H., Stein Claudia, Mangen, M, Pinheiro, P, Paulo Pinheiro, Beate Jahn, Mangen Marie-Josée J., Havelaar, AH, Cassini, Alessandro, Fèvre Eric M., Havelaar, A, Pinheiro, Paulo, Fevre, Eric, Longhi, Silvia, Havelaar, Arie H, Lai, Taavi, Fèvre, Eric M, Stein, C, Mangen, Marie-Josée J, Longhi, S, Beate Jahn (170765), Mirjam Kretzschmar, Mirjam Kretzschmar (27309), ?, ?, Longhi Silvia, Fèvre, EM, Mangen, M.J.J., Stein, C., Mangen, Marie-Josee E. J., Stein, C,, Cassini Alessandro, Eric M. Fèvre (125784), Pinheiro, Joao Paulo, Mangen, M.J., Pinheiro Paulo, Arie H. Havelaar (170779), Alessandro Cassini (170788), Risk Assessment of Toxic and Immunomodulatory Agents, Taavi Lai, Havelaar, A.H., Kramarz, Piotr, Arie H Havelaar, Kretzschmar Mirjam, Jahn, B., Cassini, A., BCoDE consortium, x, Lai, T, Kramarz, P, Piotr Kramarz (170792), Stein, Claudia, Kramarz Piotr, Jahn, Beate, Fèvre, E, Cassini, A, Marie-Josée J Mangen, Marie-Josée J. Mangen (170760), Havelaar, Arie H., Kretzschmar, M.E.E., Pinheiro, P., Silvia Longhi (170771), Jahn, B, Eric M Fèvre, Ricciardi, Gualtiero, Kretzschmar, M., Paulo Pinheiro (170764), Jahn Beate, Franco, E, Lai, T., Kramarz, P., Alessandro Cassini, Longhi, S., Taavi Lai (170775), Claudia Stein (170785), Silvia Longhi, Kretzschmar, M   +85 more
core   +2 more sources

Nutritional burden from the global burden of disease

Archives of Medical Science
Material and methodsWe used data from the Global Burden of Disease Study 2019 to calculate the incidence rates of and estimated annual percentage changes (EAPCs) in disability-adjusted life-years (DALYs) due to nutritional deficiencies in 204 countries and territories from 1990 to 2019.ResultsDuring this period, the age-standardized incidence rate of ...
Jian Wang, Lan Chen, Zhu Chen
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Establishing disease models for the Belgian national burden of disease study: challenges and perspectives

The Belgian national burden of disease study (BeBOD) was launched in 2022, and currently provides disease burden estimates for 38 key diseases. The calculation of the non-fatal component of the disease burden, the Years Lived with Disability (YLD ...
B. Devleesschauwer, R. Claerman, S. Nayani, R. De Pauw   +3 more
core   +1 more source

The burden of skin diseases in China: Global Burden of Disease Study 2019

Archives of Dermatological Research
Abstract Skin diseases continue to affect human health and cause a significant disease burden on the healthcare system.We aimed to report the changing trends in the burden of skin disease in China from 1990–2019, Which has an important role in developing targeted prevention strategies.
Yaoyao, Kong, Peiye, Xing, Pengcheng, Huai, Furen, Zhang   +3 more
openaire   +2 more sources