FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Burden of Disease Analysis of COPD Attributable to Occupational PGFs in the BRICS Countries, 1990-2021. [PDF]
Int J Chron Obstruct Pulmon DisZeng J, Xie J, Huang S, Cheng J, Zeng Q.
europepmc +1 more source
How Is the Rising Burden of Kidney Disease Transforming the South Africa Dialysis Market
next move strategy consulting
openalex +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Burden of disease in adult patients with hereditary angioedema: results from a multinational survey. [PDF]
Orphanet J Rare DisWatt M +7 more
europepmc +1 more source
The burden of ambient air pollution on years of life lost from ischaemic heart disease in Pudong New Area, Shanghai [PDF]
Xing Zhong +5 more
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Sociodemographic Disparities in Pediatric Dermatological Conditions: Insights From the 2019 Global Burden of Disease Project. [PDF]
Pediatr DiscovMackenzie E +5 more
europepmc +1 more source
Tear Fluid Biomarkers For Predicting The Severity And Pathologic Burden In Alzheimer’S Disease
Yong Woo Ji
openalex +1 more source
Coping Strategies for Financial Burdens in Families with Cardiovascular Diseases in Patients Attending in Selected Public and Private Hospitals inSanàa City 2023 [PDF]
Adel Ahmed Al-Emad +2 more
openalex +1 more source