Results 41 to 50 of about 757,446 (280)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Evaluating Joint Ventures: Economic Analysis Checklist [PDF]
, 2016 This short article (for a symposium on joint ventures) provides practitioners and law professor with a 20 question checklist to guide the competitive effects analysis of the formation of a joint venture and the specific restraints and conduct of the ...
Salop, Steven C.
core +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Preponderance of the Evidence: An Ineffective Burden of Proof in Expatriation Proceedings [PDF]
, 1981 This Comment will review the recent history of evidentiary standards in expatriation proceedings. The Comment will also analyze the views espoused by the Supreme Court in the Terrazas opinion regarding the use of the preponderance standard in light of ...
Fuller, Robert Elliot
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Rules of Proof, Courts, and Incentives [PDF]
We analyze the design of legal principles and procedures for court decision-making in civil litigation. The objective is the provision of appropriate incentives for potential tort-feasors to exert care, when evidence about care is imperfect and may be ...
Claude Fluet, Dominique Demougin
core +3 more sources
Who has the burden of proof? [PDF]
Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философияThis text responds to A.Z. Chernyak's reflections on the problem of proving God's existence, which in turn were inspired by the publication of the collection "The Existence of God? Modern Positions and Approaches" (2025), edited by E.V. Loginov. I accept
Vladimir Shokhin
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Burden of Proof and Evidence-Based Reasoning in the Decisions of the Administrative Court of Justice [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒UmūmīIntroduction The admission of evidence and the burden of proving a claim are crucial elements in asserting rights in any legal proceeding, including the administrative proceeding.
Ali Mashhadi, Hormoz Yazdani Zunuz
doaj +1 more source
Exact testing with random permutations
, 2017 When permutation methods are used in practice, often a limited number of random permutations are used to decrease the computational burden. However, most theoretical literature assumes that the whole permutation group is used, and methods based on random
Goeman, Jelle, Hemerik, Jesse
core +1 more source