Results 41 to 50 of about 130,959 (294)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Les cimetières de la tène ancienne de Fontaine-Mâcon (Aube)
Revue Archéologique de l’Est, 2022 This study evaluates the finds made at the beginning of the 20th century in the three cemeteries of Fontaine-Mâcon Les Hantes/ Le Chemin des Brosses, Le Chemin des Ormeaux and Le Chemin d'Auxerre (Aube).
Luc Baray
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Global Ecology and Conservation, 2019 During the past centuries human-induced land use changes resulted in a considerable loss of natural habitats worldwide. In transformed landscapes historical burial places such as cemeteries and churchyards can have the potential for biodiversity ...
Viktor Löki +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Textiles from Scythian burial complexes
Tyragetia, 2013 In Northern Black Sea steppes were excavated more than three thousand Scythian burial mounds. In the studied burials were discovered large quantities of artifacts, but leather and textile items are preserved only in a few cases. Some ideas about Scythian
Elena Fialko, Yurii Boltryk
doaj
Cellulosolitic Microorganisms Activity as an Indicator of Details Funeral Ceremony
Нижневолжский археологический вестник, 2020 The article describes the results and the methodology for determining the initial presence of wares containing cellulose in the Vyatichi funeral ceremony in the Middle Ages in the natural zone of the southern taiga, Moscow region.
Liudmila N. Plekhanova +2 more
doaj +1 more source