Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The memorable service and monastic humility – the history of Stanisław Konarski’s heart
Folia Historica Cracoviensia, 2016 The article concentrates on an interesting 130-year-old artefact located in the Krakow church of Piarists – the decoration of the place where Stanisław Konarski’s (1700–1773) heart was buried. Konarski was a monk of the Pious Schools in the 18th century,
Ryszard Mączyński
doaj +1 more source
The Goss Farm Site (41FN12) on Bois d’Arc Creek, Fannin County, Texas [PDF]
, 2015 The Goss Farm site (41FN12) is an ancestral Caddo settlement on an alluvial landform on the west side of Bois d’Arc Creek near its confluence with the Red River.
Perttula, Timothy K.
core +1 more source
14C dating of the lime burial of Cova de Na Dent (Mallorca, Spain): optimization of the sample preparation and limitations of the method [PDF]
, 2015 Lime burials are a characteristic phenomenon of the protohistoric funerary tradition on the Balearic Islands. At Cova de Na Dent, six samples, representing the entire stratigraphy of the lime burial, were taken for analysis.
Borms, Herlinde +7 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Burial of the Scythian Period with Bridle Set in the Animal Style from the Burial Adryg
Oriental Studies, 2018 Scythian and Syberian animal style is a specific peculiarity of archeological culture in the Scythian era. The distinctive manner for animal representation is widely used in cultures of the late Bronze and early Iron Age.
M. Ochir-Gorjaeva, E. Burataev
doaj
Overwintering and regrowth of Sonchus arvensis roots in Finland as affected by fragmentation and burial in three different soil types [PDF]
, 2007 In this study the effect of root fragmentation, burial depth and soil type on overwintering and regrowth of Sonchus arvensis L.
Salonen, J., Vanhala, P.
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Oriental Studies, 2018 The major part of burial grounds of the Don and Manych basins were erected around the barrows of the Early Bronze Age. Their topography is fully determined by the character of the region’s terrain.
A. Faifert
doaj