Results 61 to 70 of about 644,317 (261)
Поволжская археологияThe article deals with the new materials in the form of archaeological complexes, obtained during excavations of catacomb burial structures of the Kultobe burial ground of the I–IV centuries in the Southern Kazakhstan, which in historical, ethnic ...
Podushkin Alexander N.
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Grób kultury ceramiki sznurowej ze stanowiska 10 w Wilczycach, pow. sandomierski
Przegląd Archeologiczny, 2017 The authors of the paper present the results of research, the subject of which was the inhumation burial of the Corded Ware culture from Wilczyce. The site is located on the culmination of the southern slope of a loess hill, rising directly above the ...
Piotr Włodarczak +5 more
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Customary international law and public goods [PDF]
, 2015 The paper examines the potential of customary international law to protect global public goods. In particular, it focuses on the question whether customary law can contribute to the mitigation of climate change.
Petersen, N., Petersen, Niels
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Pallas, 2014 During the Early Iron Age in Macedonia, metallic finds seem to occupy a more prominent place in graves than the ceramic vessels. In the necropolis of Vergina, the weapons for men and jewelries for women obviously work together to specify the social ...
Anne-Zahra Chemsseddoha
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source