Results 71 to 80 of about 79,847 (302)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The Kashi Artefacts in the Burials of the Zmeisky Catacomb Cemetery

open access: yesПоволжская археология, 2018
The paper aims to the chronology of burials within the chambers and in the undercats of the catacombs and pit interments of the Zmeisky catacomb burial ground in Republic of North Ossetia-Alania (excavations 2013–2014), based on the analysis of kashi ...
Leontyeva Anna S.
doaj   +1 more source

Comments on Caddo Origins in Northwest Louisiana [PDF]

open access: yes, 2009
This paper presents some of my thoughts on the issue of Caddo origins from the perspective of the Red River drainage in northwest Louisiana. These ideas were assembled prior to the Caddo discussion group meeting held in December 2008 and have been only ...
Girard, Jeffery S.
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The ‘invisible’ pits: how informative are old excavations in discussing Middle Palaeolithic burials?

open access: yesMateriale și Cercetări Arheologice, 2016
In this paper I focus on the potential of Palaeolithic sites excavated before the establishment of modern methods, aiming to provide reliable information on current debates. Specifically, I will address the reliability of the information coming from such
Doboș, A.
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Pagans and Christians at the frontier: Viking burial in the Danelaw [PDF]

open access: yes, 2003
[FIRST PARAGRAPH] The Vikings are the victims of cultural stereotyping (see e.g. Wawn 2000). In the popular imagination they provide the comic-book archetypal pagans: marauding shaggy war bands living and dying by the sword, with no respect for person or
Richards, J.D.
core  

Mortuary Workers, the Church, and the Funeral Trade in Late Antiquity [PDF]

open access: yes, 2013
Within the city of Constantinople, Constantine organized numerous funeral workers into associations overseen by a bishop, as part of a scheme meant to provide burials for all who needed them within the city.
Bond, Sarah E.
core   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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