Results 91 to 100 of about 29,723 (221)

Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo [PDF]

, 2016
Burkholderia cenocepacia, an opportunistic respiratory pathogen particularly relevant for cystic fibrosis patients, is difficult to eradicate due to its high level of resistance to most clinically relevant antimicrobials.
Azzalin, Alberto, Brackman, Gilles, Buroni, Silvia, Chiarelli, Laurent R, Coenye, Tom, Forneris, Federico, Israyilova, Aygun, Makarov, Vadim, Riabova, Olga, Riccardi, Giovanna, Savina, Sventlana, Scoffone, Viola C   +11 more
core   +2 more sources

The BDSF quorum sensing receptor RpfR regulates Bep exopolysaccharide synthesis in Burkholderia cenocepacia via interaction with the transcriptional regulator BerB

npj Biofilms and Microbiomes, 2022
The polysaccharide Bep is essential for in vitro biofilm formation of the opportunistic pathogen Burkholderia cenocepacia . We found that the Burkholderia diffusible signaling factor (BDSF) quorum sensing receptor RpfR is a negative regulator of the bep ...
E. Steiner, R. E. Shilling, Anja M Richter, Nadine Schmid, M. Fazli, V. Kaever, U. Jenal, T. Tolker-Nielsen, L. Eberl   +8 more
semanticscholar   +1 more source

High Confidence Prediction of Essential Genes in Burkholderia Cenocepacia

PLoS ONE, 2012
Contexte Les gènes essentiels sont absolument nécessaires à la survie d'un organisme. L'identification des gènes essentiels, en plus d'être l'une des questions les plus fondamentales en biologie, présente également un intérêt pour la science émergente de la biologie de synthèse et pour le développement de nouveaux antimicrobiens. De nouvelles thérapies
Mario Juhas, Manuel Stark, Christian von Mering, Puthapoom Lumjiaktase, Derrick W. Crook, Miguel A. Valvano, Leo Eberl   +6 more
openaire   +5 more sources

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

MicrobiologyOpen, 2022
Universal stress proteins (USPs) are ubiquitously expressed in bacteria, archaea, and eukaryotes and play a lead role in adaptation to environmental conditions.
Andrew O’Connor, Irene Jurado-Martín, Margaritha M Mysior, Anotidaishe L. Manzira, Joanna Drabinska, J. Simpson, M. Lucey, K. Schaffer, R. Berisio, S. McClean   +9 more
semanticscholar   +1 more source

A Decade of Burkholderia cenocepacia Virulence Determinant Research [PDF]

Infection and Immunity, 2010
ABSTRACT The Burkholderia cepacia complex (Bcc) is a group of genetically related environmental bacteria that can cause chronic opportunistic infections in patients with cystic fibrosis (CF) and other underlying diseases.
Loutet, S.A., Valvano, Miguel
openaire   +3 more sources

The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage [PDF]

, 2016
Burkholderia phage AP3 (vB_BceM_AP3) is a temperate virus of the Myoviridae and the Peduovirinae subfamily (P2likevirus genus). This phage specifically infects multidrug-resistant clinical Burkholderia cenocepacia lineage IIIA strains commonly isolated ...
Briers, Yves, Drulis-Kawa, Zuzanna, Holt, Giles S., Latka, Agnieszka, Lavigne, Rob, Maciejewska, Barbara, Olszak, Tomasz, Roszniowski, Bartosz, Smith, Darren L., Valvano, Miguel A., Vandenheuvel, Dieter   +10 more
core   +2 more sources

The Factors Involved in Plant–Insect–Microbe Interactions Expanded: Genome Analysis and Description of Frigoribacterium adelgis sp. nov.

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Aerobic Actinobacteria belonging to the genus Frigoribacterium were isolated from adelgid Adelges (Aphrastasia) pectinatae collected from a Korean fir tree. Genomic analysis showed that these bacteria encode a range of factors that may be involved in the interactions between Frigoribacterium strains, adelgids and/or Korean fir trees.
Gustė Tamošiūnaitė, Jekaterina Havelka, Raimonda Baranauskienė, Justas Lazutka, Nomeda Kuisiene   +4 more
wiley   +1 more source

Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms [PDF]

, 2019
Combining antibiotics with potentiators that increase their activity is a promising strategy to tackle infections caused by antibiotic-resistant bacteria.
Abatih, Emmanuel, Bové, Mona, Buroni, Silvia, Chiarelli, Laurent R, Coenye, Tom, Crabbé, Aurélie, Ostyn, Lisa, Sass, Andrea, Slachmuylders, Lisa, Van Acker, Heleen, Van Nieuwerburgh, Filip, Vandenbussche, Ian   +11 more
core   +2 more sources

Simple and effective remediation strategies of Martian perchlorates

Soil Science Society of America Journal, Volume 90, Issue 1, January/February 2026.
Abstract Martian surface minerals have abundant perchlorate salts existing in both solid and liquid phases that will impair agricultural operations, biological life‐support systems, and in situ resource utilization due to their toxicity. Thus, simple and effective perchlorate remediation strategies will be necessary for the successful use of Martian ...
Harrison R. Coker, Aenghus C. Denvir, Julie A. Howe   +2 more
wiley   +1 more source

Unravelling resistance in Burkholderia cenocepacia: Multi-omic insights into genetic and transcriptomic adaptations to sub-inhibitory antibiotic stress

Journal of Global Antimicrobial Resistance
AIM: To elucidate the molecular mechanisms driving the resistance phenotype of (Burkholderia cenocepacia under sub-inhibitory antibiotic stress BACKGROUND: The Burkholderia cepacia complex (BCC) includes 20 species of non-fermenting gram-negative ...
Himanshu Joshi, Amit Arora
doaj   +1 more source