Results 131 to 140 of about 29,723 (221)

Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial Cells [PDF]

, 2015
Members of the Burkholderia species can cause a range of severe, often fatal, respiratory diseases. A variety of in vitro models of infection have been developed in an attempt to elucidate the mechanism by which Burkholderia spp.
Graeme C. Clark, Jonathan David, Rachel E. Bell   +2 more
core   +1 more source

Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
Polymicrobial biofilms: interkingdom interactions, resistance and therapeutic stratergies. This review highlights the heightened drug resistance and complexity of polymicrobial biofilms, emphasising their persistence over mono‐species counterparts. It explores microbial interactions, resistance mechanisms and emerging strategies, including metabolite ...
Paramasivam Nithyanand, Bharath Reddy Boya, Jin‐Hyung Lee, Jintae Lee   +3 more
wiley   +1 more source

Mannitol promotes adherence of an outbreak strain of Burkholderia multivorans via an exopolysaccharide-independent mechanism that is associated with upregulation of newly identified fimbrial and afimbrial adhesins [PDF]

, 2013
© Society for General Microbiology, 2013. Post-print version of article deposited in accordance with SHERPA RoMEO guidelinesBurkholderia multivorans, a member of the Burkholderia cepacia complex (Bcc), is an important pathogen of the cystic fibrosis (CF)
Alan R. Brown, Carmen C. Denman, Clode, Mahenthiralingam, Sajjan   +4 more
core   +1 more source

Combined Forces Against Bacteria: Phages and Antibiotics

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aim It is now known that bacteria are highly interactive and exhibit a range of complex cooperative behaviors, including conjugal plasmid transfer, toxins, swarming, drug resistance, toxin production, biofilm development, and other virulence traits.
Shima Afrasiabi, Alireza Partoazar, Ramin Goudarzi, Ahmad Reza Dehpour   +3 more
wiley   +1 more source

Burkholderia cenocepacia Prophages—Prevalence, Chromosome Location and Major Genes Involved [PDF]

Viruses, 2018
Burkholderia cenocepacia, is a Gram-negative opportunistic pathogen that belongs to Burkholderia cepacia complex (BCC) group. BCC representatives carry various pathogenicity factors and can infect humans and plants. Phages as bacterial viruses play a significant role in biodiversity and ecological balance in the environment.
Bartosz Roszniowski, Siobhán McClean, Zuzanna Drulis-Kawa   +2 more
openaire   +3 more sources

The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling

Microbiology Spectrum
Drug repurposing efforts led to the discovery of bactericidal activity in auranofin, a gold-containing drug used to treat rheumatoid arthritis. Auranofin kills Gram-positive bacteria by inhibiting thioredoxin reductase, an enzyme that scavenges reactive ...
Dustin T. Maydaniuk, Brielle Martens, Sarah Iqbal, Andrew M. Hogan, Neil Lorente Cobo, Anna Motnenko, Dang Truong, Sajani H. Liyanage, Mingdi Yan, Gerd Prehna, Silvia T. Cardona   +10 more
doaj   +1 more source

Polyphasic characterisation of Burkholderia cepaciacomplex species isolated from children with cystic fibrosis

Memorias do Instituto Oswaldo Cruz, 2016
Cystic fibrosis (CF) patients with Burkholderia cepacia complex (Bcc) pulmonary infections have high morbidity and mortality. The aim of this study was to compare different methods for identification of Bcc species isolated from paediatric CF patients ...
Fernando José Vicenzi, Marcelo Pillonetto, Helena Aguilar Peres Homem de Mello de Souza, Jussara Kasuko Palmeiro, Carlos Antônio Riedi, Nelson Augusto Rosario-Filho, Libera Maria Dalla-Costa   +6 more
doaj   +1 more source

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
This bacterial enzyme, cyclase‐phosphotriesterase (C‐PTE) from Ruegeria pomeroyi DSS‐3, shows significant potential for breaking down organophosphate pollutants. Beyond its capability to hydrolyze specific plasticizers such as triphenyl phosphate and tris(2‐chloropropyl) phosphate, C‐PTE's crystal structure reveals a binuclear zinc active site, and it ...
Dawei Ji, Rebecca L. Frkic, Javad Delyami, Joachim S. Larsen, Matthew A. Spence, Colin J. Jackson   +5 more
wiley   +1 more source

Characterization of Volatile Organic Compounds Emitted from Endophytic Burkholderia cenocepacia ETR-B22 by SPME-GC-MS and Their Inhibitory Activity against Various Plant Fungal Pathogens

Molecules, 2020
The use of antagonistic microorganisms and their volatile organic compounds (VOCs) to control plant fungal pathogens is an eco-friendly and promising substitute for chemical fungicides.
Jian-Hua Chen, W. Xiang, Ke-Xin Cao, Xuan Lu, S. Yao, D. Hung, Rongshao Huang, Liang-Bo Li   +7 more
semanticscholar   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, Volume 599, Issue 12, Page 1634-1648, June 2025.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source