Results 21 to 30 of about 29,723 (221)

Identification of a system for hydroxamate xenosiderophore-mediated iron transport in Burkholderia cenocepacia. [PDF]

Microbiology (Reading)
One of the mechanisms employed by the opportunistic pathogen Burkholderia cenocepacia to acquire the essential element iron is the production and release of two ferric iron chelating compounds (siderophores), ornibactin and pyochelin. Here we show that B.
Hussein SM, Sofoluwe A, Paleja A, Duhme-Klair A, Thomas MS.   +4 more
europepmc   +2 more sources

Cell envelope structural and functional contributions to antibiotic resistance in Burkholderia cenocepacia. [PDF]

J Bacteriol
Antibiotic activity is limited by the physical construction of the Gram-negative cell envelope. Species of the Burkholderia cepacia complex (Bcc) are known as intrinsically multidrug-resistant opportunistic pathogens with low permeability cell envelopes.
Hogan AM, Motnenko A, Rahman ASMZ, Cardona ST.   +3 more
europepmc   +2 more sources

RNA-Seq reveals that Pseudomonas aeruginosa mounts growth medium-dependent competitive responses when sensing diffusible cues from Burkholderia cenocepacia. [PDF]

Commun Biol
Most habitats host diverse bacterial communities, offering opportunities for inter-species interactions. While competition might often dominate such interactions, little is known about whether bacteria can sense competitors and mount adequate responses ...
Leinweber A, Laffont C, Lardi M, Eberl L, Pessi G, Kümmerli R.   +5 more
europepmc   +2 more sources

Protozoan predation enhances stress resistance and antibiotic tolerance in Burkholderia cenocepacia by triggering the SOS response. [PDF]

ISME J
Bacterivorous protists are thought to serve as training grounds for bacterial pathogens by subjecting them to the same hostile conditions that they will encounter in the human host. Bacteria that survive intracellular digestion exhibit enhanced virulence
Morón Á, Tarhouchi AE, Belinchón I, Valenzuela JM, de Francisco P, Martín-González A, Amaro F.   +6 more
europepmc   +2 more sources

Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions. [PDF]

Vaccines (Basel)
Burkholderia cepacia complex infections remain life-threatening to cystic fibrosis patients, and due to the limited eradication efficiency of current treatments, novel antimicrobial therapies are urgently needed.
Seixas AMM, Silva C, Marques JMM, Mateus P, Rodríguez-Ortega MJ, Feliciano JR, Leitão JH, Sousa SA.   +7 more
europepmc   +2 more sources

Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection. [PDF]

Appl Microbiol Biotechnol, 2023
Small non-coding RNAs (sRNAs) are key regulators of post-transcriptional gene expression in bacteria. Despite the identification of hundreds of bacterial sRNAs, their roles on bacterial physiology and virulence remain largely unknown, as is the case of ...
Pita T, Feliciano JR, Leitão JH.
europepmc   +2 more sources

Genomic features, antimicrobial susceptibility, and epidemiological insights into Burkholderia cenocepacia clonal complex 31 isolates from bloodstream infections in India. [PDF]

Front Cell Infect Microbiol, 2023
Introduction Burkholderia cepacia complex (Bcc) clonal complex (CC) 31, the predominant lineage causing devastating outbreaks globally, has been a growing concern of infections in non-cystic fibrosis (NCF) patients in India. B.
Saroha T, Patil PP, Rana R, Kumar R, Kumar S, Singhal L, Gautam V, Patil PB.   +7 more
europepmc   +2 more sources

A Polyclonal Antibody against a Burkholderia cenocepacia OmpA-like Protein Strongly Impairs Pseudomonas aeruginosa and B. multivorans Virulence. [PDF]

Vaccines (Basel)
Despite advances in therapies, bacterial chronic respiratory infections persist as life-threatening to patients suffering from cystic fibrosis (CF). Pseudomonas aeruginosa and bacteria of the Burkholderia cepacia complex are among the most difficult of ...
Seixas AMM, Gomes SC, Silva C, Moreira LM, Leitão JH, Sousa SA.   +5 more
europepmc   +2 more sources

A <i>Burkholderia cenocepacia</i>-like environmental isolate strongly inhibits the plant fungal pathogen <i>Zymoseptoria tritici</i>. [PDF]

Appl Environ Microbiol
Fungal phytopathogens cause significant reductions in agricultural yields annually, and overusing chemical fungicides for their control leads to environmental pollution and the emergence of resistant pathogens.
Song T, Gupta S, Sorokin Y, Frenkel O, Cytryn E, Friedman J.   +5 more
europepmc   +2 more sources

Polyphosphate Kinase from Burkholderia cenocepacia, One Enzyme Catalyzing a Two-Step Cascade Reaction to Synthesize ATP from AMP. [PDF]

Int J Mol Sci
This study characterizes a novel polyphosphate kinase from Burkholderia cenocepacia (BcPPK2-III), an enzyme with potential applications in ATP regeneration processes.
Monterrey DT, Azcona L, Revuelta J, Sánchez-Moreno I, García-Junceda E.   +4 more
europepmc   +2 more sources