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Phage therapy to treat cystic fibrosis Burkholderia cepacia complex lung infections: perspectives and challenges [PDF]

Frontiers in Microbiology
Burkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.
Jack S. Canning, Jack S. Canning, Daniel R. Laucirica, Kak-Ming Ling, Kak-Ming Ling, Mark P. Nicol, Stephen M. Stick, Stephen M. Stick, Stephen M. Stick, Anthony Kicic, Anthony Kicic, Anthony Kicic   +11 more
doaj   +2 more sources

Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure [PDF]

, 2017
The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infection.
Peeters, Charlotte, Cooper, Vaughn S, Hatcher, Philip J, Verheyde, Bart, Carlier, Aurélien, Vandamme, Peter   +5 more
core   +31 more sources

Burkholderia cepacia bronchiectasis [PDF]

Thorax, 1999
We read with interest the case report by Ledson et al 1 describing a non-cystic fibrosis individual with chronic Burkholderia cepacia bronchiectasis. Although B cepacia most commonly affects patients with cystic fibrosis, it is also known to infect patients with chronic ventilatory requirements or immunocompromised patients.2 The immunocompromised ...
S SURESH, I. DOULL;, M. LEDSON, M. WALSHAW   +3 more
openaire   +2 more sources

Community Acquired Burkholderia cepacia Bacteraemia Presenting as MODS in an Immunocompetent Individual: An Unusual Case [PDF]

Journal of Clinical and Diagnostic Research, 2017
Burkholderia cepacia has been recognized as a group of highly virulent organisms known as Burkholderia cepacia complex (Bcc). Bcc are ubiquitous in nature and most commonly found in moist environment, on plant roots and soil.
Ritesh Ranjan, Priti Chowdhary, Aman Kamra   +2 more
doaj   +1 more source

Presence of the Hmq System and Production of 4-Hydroxy-3-Methyl-2-Alkylquinolines Are Heterogeneously Distributed between Burkholderia cepacia Complex Species and More Prevalent among Environmental than Clinical Isolates

Microbiology Spectrum, 2021
The Burkholderia cepacia complex (Bcc) comprises several species of closely related, versatile bacteria. Some Bcc strains produce 4-hydroxy-3-methyl-2-alkylquinolines (HMAQs), analogous to the 4-hydroxy-2-alkylquinolines of Pseudomonas aeruginosa.
Pauline M. L. Coulon, James E. A. Zlosnik, Eric Déziel   +2 more
doaj   +1 more source

The great mimicker “Burkholderia cepacia”: A case of intra-abdominal abscesses [PDF]

Journal of Krishna Institute of Medical Sciences University, 2023
Burkholderia cepacia infections are underreported and often seen in immunocompromised or cystic fibrosis patients. We describe a case of intra-abdominal abscesses and bacteraemia due to Burkholderia cepacia in a non-cystic fibrosis patient. A middle aged
Divya Prabhu, Guru Prasad Ravikumar, Ashwin Kulkarni, Megha Gopal   +3 more
doaj  

Burkholderia Infections in Diabetic Section Patients Emerging as a Challenge for Physicians: A Case Series [PDF]

Journal of Clinical and Diagnostic Research, 2019
The genus Burkholderia comprises more than 40 species. Medically important members of this genus are Burkholderia cepacia (B.cepacia), Burkholderia pseudomallei (B.pseudomallei) and Burkholderia mallei (B.mallei).
SHUBHRANSU PATRO, SUDHANSU SEKHAR PANDA, DEBASHISH MISHRA, SONAPURAM KEERTHI   +3 more
doaj   +1 more source

Cepacia Causing Nosocomial Urinary Tract Infection in Children [PDF]

Childhood Kidney Diseases, 2015
Purpose: Burkholderia cepacia is an aerobic, glucose–non-fermenting, gram-negative bacillus that mainly affects immunocompromised and hospitalized patients.
Ki Wuk Lee, Sang Taek Lee, Heeyeon Cho
doaj   +1 more source

Community-Acquired burkholderia cepacia complex (BCC) pneumonia in a lung cancer patient on erlotinib

Lung India, 2023
Community-acquired Burkholderia cepacia pneumonia is uncommon. We report a 32-year-old female who was on oral erlotinib, a tyrosine kinase inhibitor, for 2 years for her lung cancer and developed community-acquired Burkholderia cepacia pneumonia, which ...
Prasanta Raghab Mohapatra, Rohit Bicaro Shirgaonkar, Bijayini Behera, Aswathy Girija   +3 more
doaj   +1 more source

Burkholderia cepacia keratitis with endophthalmitis [PDF]

Journal of Medical Microbiology, 2009
Keratitis with endophthalmitis of the right eye occurred in a 78-year-female following a complicated cataract surgery. Prompt intravitreal vancomycin and ceftazidime with topical fortified tobramycin and cefazolin treatments were started. The corneal, aqueous and vitreous cultures grew a Burkholderia cepacia complex (Bcc) strain on the fourth day ...
Örnek, Kemal, Özdemir, Mehmet, Ergin, Ahmet   +2 more
openaire   +2 more sources