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The genus Burkholderia contains over 80 different Gram-negative species including both plant and human pathogens, the latter of which can be classified into one of two groups: the Burkholderia pseudomallei complex (Bpc) or the Burkholderia cepacia ...
Irum Syed, R. Mark Wooten
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We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Guanbo Wang +6 more
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Burkholderia vietnamiensis Bacteraemia After Lung Transplantation in a Patient With Diffuse Panbronchiolitis [PDF]
Lung transplant recipients are at risk of opportunistic infections because of immunosuppression. We report a case of Burkholderia vietnamiensis bacteraemia that occurred 3 months after bilateral lung transplantation for diffuse panbronchiolitis ...
Taiki Ryo +2 more
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Misidentification of Burkholderia pseudomallei and Other Burkholderia Species From Pediatric Infections in Mexico [PDF]
Abstract Burkholderia pseudomallei and Burkholderia cepacia complex are poorly studied in Mexico. The genotypic analysis of 38 strains isolated from children with pneumonia were identified and showed that both Burkholderia groups were present in patients.
Alfredo Torres +2 more
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Burkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.
Jack S. Canning +11 more
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Burkholderia stabilis infections associated with contamination of non-sterile alcohol-free skin cleansing wipes, United Kingdom, 2018 to 2026 [PDF]
A Burkholderia stabilis (ST480) outbreak associated with skin cleansing wipes has comprised 59 confirmed cases in the United Kingdom 2018–2026. Cases included patients with co-morbidities and clinically relevant infections. There was one associated death.
James Elston
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Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines
Increasing antimicrobial resistance due to misuse and overuse of antimicrobials, as well as a lack of new and innovative antibiotics in development has become an alarming global threat.
Megan E. Grund +4 more
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Current Advances in Burkholderia Vaccines Development
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang +2 more
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New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates
Bacteria of the genus Burkholderia include pathogenic Burkholderia mallei, Burkholderia pseudomallei and the Burkholderia cepacia complex (Bcc). These Gram-negative pathogens have intrinsic drug resistance, which makes treatment of infections difficult ...
Dustin Maydaniuk +7 more
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Intra-abdominal Abscesses by Burkholderia cepacia in Poorly Controlled Diabetes Mellitus: A Case Series [PDF]
Burkholderia is a gram-negative bacillus causing infections in immunocompromised patients. It is commonly seen in the tropics and is known to mimic tuberculosis clinically.
Aditya Dhanawat +3 more
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