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Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The genus Burkholderia contains over 80 different Gram-negative species including both plant and human pathogens, the latter of which can be classified into one of two groups: the Burkholderia pseudomallei complex (Bpc) or the Burkholderia cepacia ...
Irum Syed, R. Mark Wooten
doaj   +3 more sources

A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections

open access: yesVirulence, 2021
We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Guanbo Wang   +6 more
doaj   +2 more sources

Burkholderia vietnamiensis Bacteraemia After Lung Transplantation in a Patient With Diffuse Panbronchiolitis [PDF]

open access: yesRespirology Case Reports
Lung transplant recipients are at risk of opportunistic infections because of immunosuppression. We report a case of Burkholderia vietnamiensis bacteraemia that occurred 3 months after bilateral lung transplantation for diffuse panbronchiolitis ...
Taiki Ryo   +2 more
doaj   +2 more sources

Misidentification of Burkholderia pseudomallei and Other Burkholderia Species From Pediatric Infections in Mexico [PDF]

open access: yesOpen Forum Infectious Diseases, 2019
Abstract Burkholderia pseudomallei and Burkholderia cepacia complex are poorly studied in Mexico. The genotypic analysis of 38 strains isolated from children with pneumonia were identified and showed that both Burkholderia groups were present in patients.
Alfredo Torres   +2 more
exaly   +3 more sources

Phage therapy to treat cystic fibrosis Burkholderia cepacia complex lung infections: perspectives and challenges

open access: yesFrontiers in Microbiology
Burkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.
Jack S. Canning   +11 more
doaj   +3 more sources

Burkholderia stabilis infections associated with contamination of non-sterile alcohol-free skin cleansing wipes, United Kingdom, 2018 to 2026 [PDF]

open access: yesEurosurveillance
A Burkholderia stabilis (ST480) outbreak associated with skin cleansing wipes has comprised 59 confirmed cases in the United Kingdom 2018–2026. Cases included patients with co-morbidities and clinically relevant infections. There was one associated death.
James Elston
doaj   +2 more sources

Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines

open access: yesCells, 2021
Increasing antimicrobial resistance due to misuse and overuse of antimicrobials, as well as a lack of new and innovative antibiotics in development has become an alarming global threat.
Megan E. Grund   +4 more
doaj   +1 more source

Current Advances in Burkholderia Vaccines Development

open access: yesCells, 2020
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang   +2 more
doaj   +1 more source

New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates

open access: yesAntibiotics, 2021
Bacteria of the genus Burkholderia include pathogenic Burkholderia mallei, Burkholderia pseudomallei and the Burkholderia cepacia complex (Bcc). These Gram-negative pathogens have intrinsic drug resistance, which makes treatment of infections difficult ...
Dustin Maydaniuk   +7 more
doaj   +1 more source

Intra-abdominal Abscesses by Burkholderia cepacia in Poorly Controlled Diabetes Mellitus: A Case Series [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Burkholderia is a gram-negative bacillus causing infections in immunocompromised patients. It is commonly seen in the tropics and is known to mimic tuberculosis clinically.
Aditya Dhanawat   +3 more
doaj   +1 more source

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