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A case report of a patient with chronic granulomatous disease complicated by invasive aspergillosis and disseminated Burkholderia multivorans infection [PDF]

open access: yesFrontiers in Medicine
BackgroundChronic granulomatous disease (CGD) is a rare inborn error of immunity characterized by defective phagocyte oxidative burst, leading to recurrent, life-threatening infections with catalase-positive bacteria and fungi.
Xuanwen Weng   +4 more
doaj   +2 more sources

A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections

open access: yesVirulence, 2021
We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Karine Laroucau   +2 more
exaly   +2 more sources

Current Advances in Burkholderia Vaccines Development

open access: yesCells, 2020
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang   +2 more
doaj   +2 more sources

Burkholderia vietnamiensis Bacteraemia After Lung Transplantation in a Patient With Diffuse Panbronchiolitis [PDF]

open access: yesRespirology Case Reports
Lung transplant recipients are at risk of opportunistic infections because of immunosuppression. We report a case of Burkholderia vietnamiensis bacteraemia that occurred 3 months after bilateral lung transplantation for diffuse panbronchiolitis ...
Taiki Ryo   +2 more
doaj   +2 more sources

Genetic regulation of biosynthesis and resistance to redox-active phenazines in Burkholderia spp. [PDF]

open access: yesMicrobiology Spectrum
Burkholderia includes gram-negative saprophytes, nitrogen-fixers, and species associated with nosocomial infections. Numerous strains in the Burkholderia cepacia, Burkholderia pseudomallei, Burkholderia glumae, and Burkholderia gladioli clades carry ...
Ankita Bhattacharyya   +6 more
doaj   +2 more sources

Burkholderia stabilis infections associated with contamination of non-sterile alcohol-free skin cleansing wipes, United Kingdom, 2018 to 2026 [PDF]

open access: yesEurosurveillance
A Burkholderia stabilis (ST480) outbreak associated with skin cleansing wipes has comprised 59 confirmed cases in the United Kingdom 2018–2026. Cases included patients with co-morbidities and clinically relevant infections. There was one associated death.
James Elston
doaj   +2 more sources

Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The genus Burkholderia contains over 80 different Gram-negative species including both plant and human pathogens, the latter of which can be classified into one of two groups: the Burkholderia pseudomallei complex (Bpc) or the Burkholderia cepacia ...
Irum Syed, R. Mark Wooten
doaj   +1 more source

Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines

open access: yesCells, 2021
Increasing antimicrobial resistance due to misuse and overuse of antimicrobials, as well as a lack of new and innovative antibiotics in development has become an alarming global threat.
Megan E. Grund   +4 more
doaj   +1 more source

Unusual Violet Coloured Pigment Produced by Burkholderia cepacia Complex – A Report of Five Cases from a Tertiary Care Hospital in Mumbai

open access: yesJournal of Medical Sciences and Health, 2022
Burkholderia cepacia complex (BCC) represent a group of opportunistic organisms that cause a wide variety of infections including the nosocomial.
Anuradha De   +4 more
doaj   +1 more source

New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates

open access: yesAntibiotics, 2021
Bacteria of the genus Burkholderia include pathogenic Burkholderia mallei, Burkholderia pseudomallei and the Burkholderia cepacia complex (Bcc). These Gram-negative pathogens have intrinsic drug resistance, which makes treatment of infections difficult ...
Dustin Maydaniuk   +7 more
doaj   +1 more source

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