Bacterial drug tolerance under clinical conditions is governed by anaerobic adaptation but not anaerobic respiration [PDF]
Non-inherited antibiotic resistance is a phenomenon whereby a subpopulation of genetically identical bacteria displays phenotypic tolerance to antibiotics. We show that, compared to E. coli, the clinically relevant genus Burkholderia displays much higher
Butler, Clive S. +5 more
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Burkholderia gladioli sinonasal infection
Burkholderia gladioli are non-fermenting, Gram-negative, rod-shaped aerobic bacteria that were first identified as a plant pathogen. Most of the B. gladioli infections reported in the literature have involved immunocompromised adults and newborn infants. B.
C. Zanotti +3 more
openaire +2 more sources
The changing epidemiology of Burkholderia species infection at an adult cystic fibrosis centre [PDF]
Background: This study reviews the impact of changing infection control practices at the Manchester Adult Cystic Fibrosis Centre (MACFC) upon the epidemiology of Burkholderia species infections.Methods: We reviewed strain and genomovar typing of all ...
Doherty, Catherine J. +5 more
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Burkholderia Infections in Diabetic Section Patients Emerging as a Challenge for Physicians: A Case Series [PDF]
The genus Burkholderia comprises more than 40 species. Medically important members of this genus are Burkholderia cepacia (B.cepacia), Burkholderia pseudomallei (B.pseudomallei) and Burkholderia mallei (B.mallei).
SHUBHRANSU PATRO +3 more
doaj +1 more source
Development of vaccines against burkholderia pseudomallei. [PDF]
Burkholderia pseudomallei is a Gram-negative bacterium which is the causative agent of melioidosis, a disease which carries a high mortality and morbidity rate in endemic areas of South East Asia and Northern Australia.
Patel, Natasha +23 more
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Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. [PDF]
UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its ...
Richard W. Titball +49 more
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An unusual case of primary melioidotic prostatic abscess complicated by perianal abscess
Burkholderia pseudomallei is recognized to cause severe and fatal infections. Most of the infections caused by this facultative intracellular gram-negative bacterium are pneumonia, soft tissue, genito-urinary and central nervous system infection.
Y.C. Chee, Y.N. Chee
doaj +1 more source
Diversity of the parB and repA genes of the Burkholderia cepacia complex and their utility for rapid identification of Burkholderia cenocepacia [PDF]
Background: Burkholderia cenocepacia is the most prominent species of the B. cepacia complex (Bcc), a group of nine closely related and difficult to identify bacteria that cause serious infections in patients with cystic fibrosis.
Mahenthiralingam Eshwar +14 more
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Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Panda, G. +32 more
core +1 more source
T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis. [PDF]
There is an urgent need for a better understanding of adaptive immunity to Burkholderia pseudomallei, the causative agent of melioidosis that is frequently associated with sepsis or death in patients in Southeast Asia and Northern Australia.
Sumonwiriya, M +41 more
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