A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections [PDF]
Virulence, 2021 We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Guanbo Wang +6 more
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Phage therapy to treat cystic fibrosis Burkholderia cepacia complex lung infections: perspectives and challenges [PDF]
Frontiers in MicrobiologyBurkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.
Jack S. Canning +11 more
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Current Advances in Burkholderia Vaccines Development
Cells, 2020 The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang +2 more
doaj +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 The genus Burkholderia contains over 80 different Gram-negative species including both plant and human pathogens, the latter of which can be classified into one of two groups: the Burkholderia pseudomallei complex (Bpc) or the Burkholderia cepacia ...
Irum Syed, R. Mark Wooten
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The clinical, microbiological, and demographic aspects of Burkholderia infections: insights from a tertiary healthcare setting [PDF]
Romanian Journal of Infectious DiseasesBackground and objectives. Optimal management requires an understanding of Burkholderia infections demographic, clinical, microbiological, and antibiotic features.
K.I.S.N. Vaishnavi +2 more
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Burkholderia multivorans: A rare yet emerging cause of bacterial meningitis
IDCases, 2018 Burkholderia multivorans is a member of the Burkholderia cepacia complex. Although it is usually associated with infections in patients with cystic fibrosis, chronic granulomatous disease, and immunosuppression, central nervous infections are not ...
Diego P. Peralta +3 more
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Misidentification of Burkholderia pseudomallei and Other Burkholderia Species From Pediatric Infections in Mexico [PDF]
Open Forum Infectious Diseases, 2019 Abstract Burkholderia pseudomallei and Burkholderia cepacia complex are poorly studied in Mexico. The genotypic analysis of 38 strains isolated from children with pneumonia were identified and showed that both Burkholderia groups were present in patients.
Marcos R Escobedo-Guerra +2 more
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Burkholderia vietnamiensis Bacteraemia After Lung Transplantation in a Patient With Diffuse Panbronchiolitis [PDF]
Respirology Case ReportsLung transplant recipients are at risk of opportunistic infections because of immunosuppression. We report a case of Burkholderia vietnamiensis bacteraemia that occurred 3 months after bilateral lung transplantation for diffuse panbronchiolitis ...
Taiki Ryo +2 more
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Hospital-Based Cross-Sectional Study of <i>Burkholderia pseudomallei</i> Seroreactivity Among Febrile Patients in Northernmost Vietnam: Near-Neighbor Bloodstream Isolates, Environmental Correlates, and Spatial Clustering. [PDF]
GeohealthAbstract Melioidosis is a potentially fatal tropical disease caused by the environmentally mediated bacterium, Burkholderia pseudomallei. In Vietnam, melioidosis is not nationally reportable and little is known regarding its epidemiology and distribution in the northernmost mountainous provinces.
Metrailer MC +14 more
europepmc +2 more sources
Burkholderia stabilis infections associated with contamination of non-sterile alcohol-free skin cleansing wipes, United Kingdom, 2018 to 2026 [PDF]
EurosurveillanceA Burkholderia stabilis (ST480) outbreak associated with skin cleansing wipes has comprised 59 confirmed cases in the United Kingdom 2018–2026. Cases included patients with co-morbidities and clinically relevant infections. There was one associated death.
James Elston
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