The Changing Transplant Landscape in the Era of Elexacaftor/Tezacaftor/Ivacaftor: A Word of Caution
Clinical Transplantation, Volume 39, Issue 10, October 2025.ABSTRACT Background Elexacaftor/tezacaftor/ivacaftor (ETI) has dramatically changed the landscape of cystic fibrosis (CF) care, including in those who require lung transplantation. The objectives of the study were to describe the cohort demographics and outcomes of primary lung transplant recipients before and after the availability of ETI.
Julie Semenchuk +8 more
wiley +1 more source
The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage [PDF]
, 2016 Burkholderia phage AP3 (vB_BceM_AP3) is a temperate virus of the Myoviridae and the Peduovirinae subfamily (P2likevirus genus). This phage specifically infects multidrug-resistant clinical Burkholderia cenocepacia lineage IIIA strains commonly isolated ...
Briers, Yves +10 more
core +2 more sources
Antimicrobial susceptibility patterns of unusual nonfermentative gram-negative bacilli isolated from Latin America: report from the SENTRY Antimicrobial Surveillance Program (1997-2002) [PDF]
, 2005 The antimicrobial susceptibility of 176 unusual non-fermentative gram-negative bacilli (NF-GNB) collected from Latin America region through the SENTRY Program between 1997 and 2002 was evaluated by broth microdilution according to the National Committee ...
Andrade, Soraya Sgambatti +3 more
core +3 more sources
Development and evaluation of an in-house database for quick identification of Burkholderia contaminans by MALDI-TOF MS [PDF]
, 2019 La espectrometría de masas (EM) (matrix assisted laser desorption ionization-time of flight) MALDI-TOF demostró ser una herramienta robusta para la identificación de numerosos grupos taxonómicos. No obstante, presenta limitaciones.
Almuzara, Marisa +7 more
core +1 more source
Promising Prodiginins Biological Activities
Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Diverse pathogenicity of Burkholderia cepacia complex strains in the Caenorhabditis elegans host model [PDF]
, 2017 A fast screening method was developed to assess the pathogenicity of a diverse collection of environmental and clinical Burkholderia cepacia complex isolates in the nematode Caenorhabditis elegans. The method was validated by comparison with the standard
Cardona, Silvia T. +3 more
core
A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water [PDF]
, 2015 Background: Water and High Purity Water (HPW) distribution systems can be contaminated with human pathogenic microorganisms. This biocontamination may pose a risk to human health as HPW is commonly used in the industrial, pharmaceutical and clinical ...
Barry, Thomas +4 more
core +3 more sources
Aging Cell, Volume 24, Issue 9, September 2025.Cigarette exposure can induce the senescence of retinal pigment epithelium (RPE). The accumulation of naphthalene metabolites, namely 1,2‐dihydronaphthalene and 1,2‐naphthoquinone, in rats is a key factor in this process. In ARPE‐19 cells, the plasma of rats exposed to cigarette smoke can cause a significant increase in the level of reactive oxygen ...
Tingting Cui +16 more
wiley +1 more source
Medical Laboratory Journal, 2014 Background and Objective: Burkholderia cepacia complex (BCC) is a plant pathogen that is an important mortality factor in immune-compromised and hospitalized patients.
M Elmi Merian, M Faezi Ghasemi
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Мать и дитя в Кузбассе, 2022 Cystic fibrosis is an autosomal recessive disease characterized by involvement of all exocrine glands, vital organs and systems. CFTR protein dysfunction leads to chronic infection and subsequent uncontrolled inflammation.
Яков Яковлевич Яковлев +5 more
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