Influence of Neutrophil Defects on Burkholderia cepacia Complex Pathogenesis [PDF]
The Burkholderia cepacia complex (Bcc) is a group of Gram-negative bacteria that are ubiquitous in the environment and have emerged as opportunistic pathogens in immunocompromised patients. The primary patient populations infected with Bcc include individuals with cystic fibrosis (CF), as well as those with chronic granulomatous disease (CGD).
Porter, Laura A., Goldberg, Joanna B.
openaire +3 more sources
Environmental Burkholderia cenocepacia Strain Enhances Fitness by Serial Passages during Long-Term Chronic Airways Infection in Mice [PDF]
Burkholderia cenocepacia is an important opportunistic pathogen in cystic fibrosis (CF) patients, and has also been isolated from natural environments. In previous work, we explored the virulence and pathogenic potential of environmental B.
Ascenzioni, Fiorentina +5 more
core +3 more sources
DNA-Based Diagnostic Approaches for Identification of Burkholderia cepacia Complex, Burkholderia vietnamiensis, Burkholderia multivorans,Burkholderia stabilis, and Burkholderia cepacia Genomovars I and III [PDF]
Bacteria of the Burkholderia cepacia complex consist of five discrete genomic species, including genomovars I and III and three new species: Burkholderia multivorans (formerly genomovar II), Burkholderia stabilis (formerly genomovar IV), andBurkholderia vietnamiensis (formerly genomovar V).
E, Mahenthiralingam +6 more
openaire +2 more sources
A collection of 161 Ralstonia isolates, including 90 isolates from persons with cystic fibrosis, 27 isolates from other human clinical samples, 8 isolates from the hospital environment, 7 isolates from industrial samples, and 19 environmental isolates ...
Stephanie Steyaert +9 more
doaj +1 more source
The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth [PDF]
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical ...
Braeckmans, Kevin +12 more
core +1 more source
IntroductionThe Burkholderia cepacia complex (BCC) encompasses a group of at least 22 genetically distinct gram-negatives bacterial species ubiquitous in nature.
Amy Pham +13 more
doaj +1 more source
First time identification of Pandoraea sputorum from a patient with cystic fibrosis in Argentina: a case report [PDF]
Background: Pandoraea species are considered emerging pathogens in the context of cystic fibrosis (CF) and are difficult to identify by conventional biochemical methods. These multidrug resistant bacteria remain poorly understood particularly in terms of
Alvarez, Florencia +11 more
core +2 more sources
A Machine Learning-Based Raman Spectroscopic Assay for the Identification of Burkholderia mallei and Related Species [PDF]
Burkholderia (B.) mallei, the causative agent of glanders, and B. pseudomallei, the causative agent of melioidosis in humans and animals, are genetically closely related. The high infectious potential of both organisms, their serological cross-reactivity,
Bocklitz, Thomas +8 more
core +2 more sources
Background. Chronic granulomatous disease is a rare inherited disorder of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. The clinical course of the disease is marked by recurrent infections, including Burkholderia cepacia ...
Maxime Maignan +4 more
doaj +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources

