Results 61 to 70 of about 7,998 (179)

Burkholderia cepacia complex infections beyond hospital outbreaks: A 22-Year analysis of clinical characteristics, antimicrobial resistance, and mortality predictors

Journal of Infection and Public Health
Background: Burkholderia cepacia complex bacteria are intrinsically multidrug-resistant opportunistic pathogens that pose a growing threat in hospital settings, particularly among immunocompromised patients.
Marwan Jabr Alwazzeh, Amani Alnimr, Sara M. Alwarthan, Mashael Alhajri, Jumanah Algazaq, Bashayer M. AlShehail, Basel A. Darweesh, Mohammed A. Basheikh, Reem S. AlSulaiman, Saud A. Alamro, Jawad ur Rahman, Mohammad T. Al-Hariri   +11 more
doaj   +1 more source

Lipase Stability in Structured Lipid Synthesis: The Interplay of Substrate Characteristics and Strategies to Improve Its Operational Performance—A Critical Review

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Structured lipids (SLs) have attracted growing industrial interest due to their associated health benefits. Lipases, as highly selective and versatile biocatalysts, are central to the sustainable synthesis of SLs attributed to their ability to operate under mild reaction conditions. However, the limited operational stability of lipases remains
Evelyn Ling Lee, Eng‐Seng Chan, Lee Fong Siow, Cher Pin Song, Yee‐Ying Lee   +4 more
wiley   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Molecular identification of Burkholderia cepacia complex from people with cystic fibrosis in northwestern Iran: a research note

BMC Research Notes
Objective The objective of this study was to identify the Burkholderia cepacia complex in patients with cystic fibrosis in northwestern Iran using conventional culture.
Amir Hossein Jafari-Rouhi, Hassan Tizfahm Tikmehdash, Nader Mosavari, Leila Vahedi   +3 more
doaj   +1 more source

Function and Structure Relationships With Inflammation Differ in Two Chronic Suppurative Lung Diseases

Pediatric Pulmonology, Volume 61, Issue 5, May 2026.
ABSTRACT Rationale Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are characterized by neutrophilic airway inflammation but differ in clinical features. Objectives We investigated relationships of pulmonary and systemic inflammatory markers with functional and structural lung disease.
Teresa Fuchs, Jacqueline Donovan, Andrew Ives, Samantha Irving, Gwyneth Davies, Claire Hogg, Eric Alton, Gemma Wilson, Andrew Bush, Jane C. Davies   +9 more
wiley   +1 more source

Burkholderia semiarida as Cause of Recurrent Pulmonary Infection in Immunocompetent Patient, China

Emerging Infectious Diseases
Burkholderia semiarida was previously identified solely as a plant pathogen within the Burkholderia cepacia complex. We present a case in China involving recurrent pneumonia attributed to B. semiarida infection.
Dai Kuang, Feng Liu, Shen Tian, Wei Liu, Anyang Li, Yujing Zhou, Huaping Huang, Qianfeng Xia   +7 more
doaj   +1 more source

Follow‐Up of Children With Primary Ciliary Dyskinesia

Pediatric Pulmonology, Volume 61, Issue 5, May 2026.
ABSTRACT Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder resulting in defective ciliary motility, which leads to a spectrum of clinical manifestations, including chronic upper and lower respiratory infections, middle ear disease, situs abnormalities, congenital heart defects, and infertility.
Bruna Rubbo, Jonathan Wen Yi Ong, William Tsang, Lydia M. Newman, Jane S. Lucas   +4 more
wiley   +1 more source

Burkholderia vietnamiensis Bacteraemia After Lung Transplantation in a Patient With Diffuse Panbronchiolitis

Respirology Case Reports, Volume 14, Issue 5, May 2026.
Persistent Burkholderia cepacia complex bacteraemia occurred after lung transplantation for diffuse panbronchiolitis. Despite apparent in vitro susceptibility to meropenem, bacteraemia persisted and antimicrobial therapy was modified. This case highlights the importance of integrating clinical evolution with antimicrobial susceptibility testing when ...
Taiki Ryo, Ken‐ichi Iwata, Toyofumi Fengshi Chen‐Yoshikawa   +2 more
wiley   +1 more source

Antibodies to Burkholderia pseudomallei Outer Membrane Proteins Coupled to Nanovaccines Exhibit Cross-Reactivity to B. cepacia Complex and Pseudomonas aeruginosa Homologues

Microorganisms
Burkholderia pseudomallei complex and B. cepacia complex are two evolutionary distinct clades of pathogens causing human disease. Most vaccine efforts have focused on the former group largely due to their biothreat status and global disease burden.
Alexander J. Badten, Susana Oaxaca-Torres, Alfredo G. Torres   +2 more
doaj   +1 more source

Cepacia-Like Syndrome Caused by Burkholderia mutivorans

Canadian Journal of Infectious Diseases, 2003
The variable severity of Burkholderia cepacia complex infections in cystic fibrosis (CF) has recently been ascribed to differences in the virulence between genomovars.
George Zahariadis, Michelle H Levy, Jane L Burns   +2 more
doaj   +1 more source