Results 41 to 50 of about 17,817 (209)

The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]

, 2016
Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie, Devos, Simon, Devreese, Bart   +2 more
core   +2 more sources

Influence of Neutrophil Defects on Burkholderia cepacia Complex Pathogenesis [PDF]

Frontiers in Cellular and Infection Microbiology, 2011
The Burkholderia cepacia complex (Bcc) is a group of Gram-negative bacteria that are ubiquitous in the environment and have emerged as opportunistic pathogens in immunocompromised patients. The primary patient populations infected with Bcc include individuals with cystic fibrosis (CF), as well as those with chronic granulomatous disease (CGD).
Porter, Laura A., Goldberg, Joanna B.
openaire   +3 more sources

Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]

, 2017
Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom, Kiekens, Sanne, Sass, Andrea   +2 more
core   +3 more sources

Phylogenomic study of Burkholderia glathei-like organisms, proposal of 13 novel Burkholderia species and emended descriptions of Burkholderia sordidicola, Burkholderia zhejiangensis, and Burkholderia grimmiae [PDF]

, 2016
Partial gyrB gene sequence analysis of 17 isolates from human and environmental sources revealed 13 clusters of strains and identified them as Burkholderia glathei Glade (BGC) bacteria.
Cooper, Vaughn S, De Brandt, Evie, Meier-Kolthoff, Jan P, Peeters, Charlotte, Vandamme, Peter, Verheyde, Bart   +5 more
core   +3 more sources

Novel Ralstonia species from human infections: improved matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based identification and analysis of antimicrobial resistance patterns

Microbiology Spectrum
A collection of 161 Ralstonia isolates, including 90 isolates from persons with cystic fibrosis, 27 isolates from other human clinical samples, 8 isolates from the hospital environment, 7 isolates from industrial samples, and 19 environmental isolates ...
Stephanie Steyaert, Charlotte Peeters, Anneleen D. Wieme, Astrid Muyldermans, Kristof Vandoorslaer, Theodore Spilker, Ingrid Wybo, Denis Piérard, John J. LiPuma, Peter Vandamme   +9 more
doaj   +1 more source

Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades

Frontiers in Microbiology, 2023
IntroductionThe Burkholderia cepacia complex (BCC) encompasses a group of at least 22 genetically distinct gram-negatives bacterial species ubiquitous in nature.
Amy Pham, Amy Pham, James G. Volmer, Daniel C. Chambers, Daniel C. Chambers, Daniel J. Smith, Daniel J. Smith, David W. Reid, David W. Reid, David W. Reid, Lucy Burr, Lucy Burr, Timothy J. Wells, Timothy J. Wells   +13 more
doaj   +1 more source

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth [PDF]

, 2019
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical ...
Braeckmans, Kevin, Coenye, Tom, Crabbé, Aurélie, Daled, Simon, De Keersmaecker, Herlinde, Deforce, Dieter, Dhaenens, Maarten, Jurėnas, Dukas, Ostyn, Lisa, Sass, Andrea, Teirlinck, Eline, Van Acker, Heleen, Van Melderen, Laurence   +12 more
core   +1 more source

Longitudinal impact of demographic and clinical variables on Health-Related Quality of Life in Cystic Fibrosis [PDF]

, 2015
Objectives: The insights that people with cystic fibrosis have concerning their health are important given that aspects of health-related quality of life (HRQoL) are independent predictors of survival and a decrease in lung function is associated with a ...
A-Rahman, Abbott, Abbott, Abbott, Arrington-Sanders, Bradley, Bradley, Dill, Duff, Feltrim, Fitzmaurice, Gee, Gee, Gee, Goldbeck, Kreft, Kugler, Lowton, Quattrucci, Quittner, Rasbash, Rodgers, Sawicki, Sawicki, Sawicki, Schmitz, Smeritschnig, Spahr, Staab, Taylor, Tierney, Ullrich, Wahl, Walters   +33 more
core   +2 more sources

Undiagnosed Chronic Granulomatous Disease, Burkholderia cepacia complex Pneumonia, and Acquired Hemophagocytic Lymphohistiocytosis: A Deadly Association

Case Reports in Pulmonology, 2013
Background. Chronic granulomatous disease is a rare inherited disorder of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. The clinical course of the disease is marked by recurrent infections, including Burkholderia cepacia ...
Maxime Maignan, Colin Verdant, Guillaume F. Bouvet, Michael Van Spall, Yves Berthiaume   +4 more
doaj   +1 more source

A Machine Learning-Based Raman Spectroscopic Assay for the Identification of Burkholderia mallei and Related Species [PDF]

, 2019
Burkholderia (B.) mallei, the causative agent of glanders, and B. pseudomallei, the causative agent of melioidosis in humans and animals, are genetically closely related. The high infectious potential of both organisms, their serological cross-reactivity,
Bocklitz, Thomas, Elschner, Mandy C., Fischer, Katja, Moawad, Amira A., Neubauer, Heinrich, Popp, Jürgen, Roesler, Uwe, Rösch, Petra, Silge, Anja   +8 more
core   +2 more sources