Results 81 to 90 of about 5,575 (204)

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source

Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway [PDF]

, 2015
© 2015 Lau et al.Background: Burkholderia pseudomallei is an emerging pathogen that causes melioidosis, a serious and potentially fatal disease which requires prolonged antibiotics to prevent relapse.
Chow, WN, Curreem, SOT, Hui, SW, Lam, CW, Lau, CY, Lau, SKP, Lee, KC, Martelli, P, Sridhar, S, Wong, SCY, Woo, PCY, Yuen, KY   +11 more
core   +1 more source

Isoelectric Focusing Fractionation Method for Signal Enhancement in Detection of Inactivated Biological Agents Using Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry

ELECTROPHORESIS, Volume 46, Issue 3-4, Page 212-220, February 2025.
ABSTRACT Timely identification of highly pathogenic bacteria is crucial for efficient mitigation of the connected harmful health effects. Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) of intact cells enables fast identification of the microorganisms based on their mass spectrometry protein fingerprint ...
Filip Duša, Jiří Šalplachta, Marie Horká, Kamila Lunerová, Veronika Čermáková, Michal Dřevínek, Oldřich Kubíček   +6 more
wiley   +1 more source

The early stage of bacterial genome-reductive evolution in the host.

PLoS Pathogens, 2010
The equine-associated obligate pathogen Burkholderia mallei was developed by reductive evolution involving a substantial portion of the genome from Burkholderia pseudomallei, a free-living opportunistic pathogen.
Han Song, Junghyun Hwang, Hyojeong Yi, Ricky L Ulrich, Yan Yu, William C Nierman, Heenam Stanley Kim   +6 more
doaj   +1 more source

Involvement of the efflux pumps in chloramphenicol selected strains of Burkholderia thailandensis: proteomic and mechanistic evidence. [PDF]

PLoS ONE, 2011
Burkholderia is a bacterial genus comprising several pathogenic species, including two species highly pathogenic for humans, B. pseudomallei and B. mallei. B. thailandensis is a weakly pathogenic species closely related to both B.
Fabrice V Biot, Eric Valade, Eric Garnotel, Jacqueline Chevalier, Claude Villard, François M Thibault, Dominique R Vidal, Jean-Marie Pagès   +7 more
doaj   +1 more source

Glanders Diagnosis in an Asymptomatic Mare from Brazil: Insights from Serology, Microbiological Culture, Mass Spectrometry, and Genome Sequencing

Pathogens, 2023
This manuscript elucidates the occurrence of glanders in an asymptomatic mare from Brazil presenting positive Burkholderia mallei antibody titers. The diagnosis was established through a multi-pronged approach encompassing microbiological culture, mass ...
Paula Adas Pereira Suniga, Cynthia Mantovani, Maria Goretti dos Santos, Andréa Alves do Egito, Newton Valério Verbisck, Lenita Ramires dos Santos, Alberto Martín Rivera Dávila, Cristina Kraemer Zimpel, Maria Carolina Sisco Zerpa, Daniela Pontes Chiebao, Ana Márcia de Sá Guimarães, Alessandra Figueiredo de Castro Nassar, Flábio Ribeiro de Araújo   +12 more
doaj   +1 more source

Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis. [PDF]

, 2017
Published onlineJournal ArticleResearch Support, Non-U.S. Gov'tThis is the final version of the article. Available from Public Library of Science via the DOI in this record.Burkholderia thailandensis, although normally avirulent for mammals, can infect ...
Basilico, F, Champion, OL, Chiaramonte, F, Consolandi, C, De Bellis, G, Falciola, L, Freddi, L, Garlanda, C, Jaillon, S, Landini, P, Mauri, P, Michell, SL, Motta, S, Peano, C, Pietrelli, A, Rossi, E   +15 more
core   +1 more source

Using real-time PCR to specifically detect Burkholderia mallei [PDF]

Journal of Medical Microbiology, 2006
Burkholderia mallei is the causative agent of human and animal glanders and is a category B biothreat agent. Rapid diagnosis of B. mallei and immediate prophylactic treatment are essential for patient survival. The majority of current bacteriological and immunological techniques for identifying B.
Melanie P, Ulrich, David A, Norwood, Deanna R, Christensen, Ricky L, Ulrich   +3 more
openaire   +2 more sources

A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface.

, 2003
To investigate Yersinia pathogenicity and the evolutionary divergence of the genus, the effect of pathogenic yersiniae on the model organism Caenorhabditis elegans was studied.
Isherwood, KE, Joshua, GWP, Karlyshev, AV, Smith, MP, Titball, RW, Wren, BW   +5 more
core   +1 more source

Rapid identification of Burkholderia mallei and Burkholderia pseudomallei by intact cell Matrix-assisted Laser Desorption/Ionisation mass spectrometric typing [PDF]

, 2012
BACKGROUND: Burkholderia (B.) pseudomallei and B. mallei are genetically closely related species. B. pseudomallei causes melioidosis in humans and animals, whereas B. mallei is the causative agent of glanders in equines and rarely also in humans.
Axel Karger, Barbara Bettin, Falk Melzer, Heinrich Neubauer, Herbert Tomaso, Holger C Scholz, Mandy C Elschner, Mario Ziller, Markus Kostrzewa, Rüdiger Stock, Thomas Maier   +10 more
core   +1 more source