Results 61 to 70 of about 2,546 (161)

The early stage of bacterial genome-reductive evolution in the host.

PLoS Pathogens, 2010
The equine-associated obligate pathogen Burkholderia mallei was developed by reductive evolution involving a substantial portion of the genome from Burkholderia pseudomallei, a free-living opportunistic pathogen.
Han Song, Junghyun Hwang, Hyojeong Yi, Ricky L Ulrich, Yan Yu, William C Nierman, Heenam Stanley Kim   +6 more
doaj   +1 more source

Involvement of the efflux pumps in chloramphenicol selected strains of Burkholderia thailandensis: proteomic and mechanistic evidence. [PDF]

PLoS ONE, 2011
Burkholderia is a bacterial genus comprising several pathogenic species, including two species highly pathogenic for humans, B. pseudomallei and B. mallei. B. thailandensis is a weakly pathogenic species closely related to both B.
Fabrice V Biot, Eric Valade, Eric Garnotel, Jacqueline Chevalier, Claude Villard, François M Thibault, Dominique R Vidal, Jean-Marie Pagès   +7 more
doaj   +1 more source

Glanders Diagnosis in an Asymptomatic Mare from Brazil: Insights from Serology, Microbiological Culture, Mass Spectrometry, and Genome Sequencing

Pathogens, 2023
This manuscript elucidates the occurrence of glanders in an asymptomatic mare from Brazil presenting positive Burkholderia mallei antibody titers. The diagnosis was established through a multi-pronged approach encompassing microbiological culture, mass ...
Paula Adas Pereira Suniga, Cynthia Mantovani, Maria Goretti dos Santos, Andréa Alves do Egito, Newton Valério Verbisck, Lenita Ramires dos Santos, Alberto Martín Rivera Dávila, Cristina Kraemer Zimpel, Maria Carolina Sisco Zerpa, Daniela Pontes Chiebao, Ana Márcia de Sá Guimarães, Alessandra Figueiredo de Castro Nassar, Flábio Ribeiro de Araújo   +12 more
doaj   +1 more source

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source

Polysaccharide microarray technology for the detection of Burkholderia pseudomallei and Burkholderia mallei antibodies

Diagnostic Microbiology and Infectious Disease, 2006
A polysaccharide microarray platform was prepared by immobilizing Burkholderia pseudomallei and Burkholderia mallei polysaccharides. This polysaccharide array was tested with success for detecting B. pseudomallei and B. mallei serum (human and animal) antibodies.
Parthasarathy, Narayanan, DeShazer, David, England, Marilyn, Waag, David M.   +3 more
openaire   +2 more sources

Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells [PDF]

BMC Microbiology, 2010
AbstractBackgroundBurkholderia pseudomalleiandBurkholderia malleicause the diseases melioidosis and glanders, respectively. A well-studied aspect of pathogenesis by these closely-related bacteria is their ability to invade and multiply within eukaryotic cells. In contrast, the means by whichB. pseudomalleiandB. malleiadhere to cells are poorly defined.
Hogan Robert J, Wooten Ronald M, Grose William, Lazarus John J, Lipski Serena, Balder Rachel, Woods Donald E, Lafontaine Eric R   +7 more
openaire   +3 more sources

Isoelectric Focusing Fractionation Method for Signal Enhancement in Detection of Inactivated Biological Agents Using Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry

ELECTROPHORESIS, Volume 46, Issue 3-4, Page 212-220, February 2025.
ABSTRACT Timely identification of highly pathogenic bacteria is crucial for efficient mitigation of the connected harmful health effects. Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) of intact cells enables fast identification of the microorganisms based on their mass spectrometry protein fingerprint ...
Filip Duša, Jiří Šalplachta, Marie Horká, Kamila Lunerová, Veronika Čermáková, Michal Dřevínek, Oldřich Kubíček   +6 more
wiley   +1 more source

DBSecSys: a database of Burkholderia malleisecretion systems [PDF]

BMC Bioinformatics, 2014
Bacterial pathogenicity represents a major public health concern worldwide. Secretion systems are a key component of bacterial pathogenicity, as they provide the means for bacterial proteins to penetrate host-cell membranes and insert themselves directly into the host cells' cytosol.
Vesna Memievi, Kamal Kumar 0002, Li Cheng, Nela Zavaljevski, David DeShazer, Anders Wallqvist, Jaques Reifman   +6 more
openaire   +2 more sources

Burkholderia pseudomallei in Colombia: Laboratory Approaches to Enhance Diagnostic Accuracy

International Journal of Microbiology, Volume 2025, Issue 1, 2025.
Background Melioidosis is a challenging disease to diagnose, and diagnostic complications can delay treatment, adversely impacting patient outcomes. Methods Over a period of 1 year, 68 isolates, initially identified as Burkholderia spp. or oxidase‐positive nonfermenting Gram‐negative bacilli (excluding Pseudomonas aeruginosa), were collected from ...
Soraya Morales-Lopez, Yeneiris Villero Wolf, Deyner Lechuga, Luis Caicedo, Yiceth Acosta Triana, Liliana Gomez, Luis Rodrigo Ramirez, Leandro Narvaez, Heidy Pinzon, Kelin Esquea, Rafael Barros, Pedro Martinez Ramos, Adriana Marin, Claudia Marcela Parra, Esha Saini   +14 more
wiley   +1 more source

Inactivation of Burkholderia mallei in Equine Serum for Laboratory Use [PDF]

Journal of Clinical Microbiology, 2015
The bacterium Burkholderia mallei is the cause of glanders. In the United Kingdom, the disease was eradicated from horses and other equids in 1928 and is now rarely reported throughout the world. Freedom from disease is maintained in part by serological screening prior to international travel.
Lorraine, Perrett, Ian, Mawhinney
openaire   +2 more sources