Results 51 to 60 of about 2,546 (161)
A comprehensive glycosylation study of diversely protected and activated d‐idopyranosyl and 6‐deoxy‐d‐ido‐heptopyranosyl donors using intra‐ and intermolecular coupling strategies is reported. Intramolecular aglycon delivery afforded 1,2‐cis‐β‐idopyranosides, while intermolecular glycosylation yielded chromatographically separable α‐ and β‐linked ...
Maude Cloutier +3 more
wiley +1 more source
Natural Burkholderia mallei Infection in Dromedary, Bahrain
We confirm a natural infection of dromedaries with glanders. Multilocus variable number tandem repeat analysis of a Burkholderia mallei strain isolated from a diseased dromedary in Bahrain revealed close genetic proximity to strain Dubai 7, which caused an outbreak of glanders in horses in the United Arab Emirates in 2004.
Ulrich Wernery +10 more
openaire +3 more sources
Characterization of an autotransporter adhesin protein shared by Burkholderia mallei and Burkholderia pseudomallei [PDF]
Autotransporters form a large family of outer membrane proteins specifying diverse biological traits of Gram-negative bacteria. In this study, we report the identification and characterization of a novel autotransporter gene product of Burkholderia mallei (locus tag BMA1027 in strain ATCC 23344).Database searches identified the gene in at least seven B.
Lafontaine, Eric R +3 more
openaire +2 more sources
Evaluation of a Latex Agglutination Assay for the Identification of Burkholderia pseudomallei and Burkholderia mallei [PDF]
Cases of melioidosis and glanders are rare in the United States, but the etiologic agents of each disease (Burkholderia pseudomallei and Burkholderia mallei, respectively) are classified as Tier 1 select agents because of concerns about their potential use as bioterrorism agents.
Duval, B +6 more
openaire +3 more sources
Background and Objective: Iran remains a major stronghold for glanders in the Middle East. In Iran, the non-indigenous Burkholderia mallei Razi 325 strain is used in manufacturing of the mallein, required for malleination of animals. Multi Locus Variable
E Faraj Tabrizi +10 more
doaj
Development of novel O-polysaccharide based glycoconjugates for immunization against glanders
Burkholderia mallei, the etiologic agent of glanders, causes severe disease in humans and animals and is a potential agent of biological warfare and terrorism. Diagnosis and treatment of glanders can be challenging, and in the absence of chemotherapeutic
Mary N Burtnick +4 more
doaj +1 more source
Burkholderia mallei and B. pseudomallei are highly pathogenic species which are closely related, but diverse regarding their prophage content. While temperate phages have not yet been isolated from B. mallei, several phages of B.
Jens A. Hammerl +5 more
doaj +1 more source
Antibody detection of Burkholderia pseudommallei and Burkholderia mallei [PDF]
Monoclonal and polyclonaI antibodies have been produced for use in immunological assays for the detection of Burkholderia pseudomallei and Burkholderia mallei. Monoclonal antibodies recognising a high molecular weight polysaccharide material found in some strains of both species have been shown to be effective in recognising B.
openaire +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Preparation of a Burkholderia Mallei Vaccine [PDF]
Abstract : Since Burkholderia mallie is of significance as an agent of bioterrorism (Category B, Centers for Disease Control, U.S.) and biological warfare, the development of effective vaccines and treatments is of particular concern. Our understanding of the disease caused by this organism is rapidly emerging, and we must move forward with our studies
openaire +1 more source

