Results 31 to 40 of about 2,537 (162)

A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection. [PDF]

PLoS ONE, 2015
Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly infectious and broad-spectrum antibiotic resistant.
Beth A Bachert, Soo J Choi, Anna K Snyder, Rita V M Rio, Brandon C Durney, Lisa A Holland, Kei Amemiya, Susan L Welkos, Joel A Bozue, Christopher K Cote, Rita Berisio, Slawomir Lukomski   +11 more
doaj   +1 more source

Current Advances in Burkholderia Vaccines Development

Cells, 2020
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang, Paulina Zarodkiewicz, Miguel A. Valvano   +2 more
doaj   +1 more source

A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections

Virulence, 2021
We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Guanbo Wang, Lena Glaser, Nichollas E. Scott, Yasmine Fathy Mohamed, Rebecca Ingram, Karine Laroucau, Miguel A. Valvano   +6 more
doaj   +1 more source

Pathogenesis ofBurkholderia pseudomalleiandBurkholderia mallei [PDF]

Military Medicine, 2009
Burkholderia pseudomallei and mallei are biological agents of military significance. There has been significant research in recent years to develop medical countermeasures for these organisms. This review summarizes work which details aspects of the pathogenesis of B.
Joseph C, Larsen, Nathan H, Johnson
openaire   +2 more sources

Evaluation of analytical-sensitivity and -specificity of a commercially available one-step real-time polymerase chain reaction assay kit for the detection of burkholderia mallei [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
Burkholderia mallei (B. mallei) is the etiological agent of glanders, a highly infectious and zoonotic disease of solipeds. Prompt and accurate detection of B. mallei and diagnosis of glanders is important for both, humans and animals.
KHAN I, ALI S, ELSCHNER M, MERTENS K, MELZER F, AHMED H, SAQIB M, IJAZ M, GWIDA M, NEUBAUER H   +9 more
doaj   +1 more source

Ribotyping ofBurkholderia malleiisolates [PDF]

FEMS Immunology & Medical Microbiology, 2005
In this study, the subspecies differentiation of 25 isolates of Burkholderia mallei was attempted based on their ribotype polymorphisms. The isolates were from human and equine infections that occurred at various times around the world. DNA samples from each isolate were digested separately with PstI and EcoRI enzymes and probed with an Escherichia ...
Steven P, Harvey, Jennifer M, Minter
openaire   +2 more sources

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Most Relevant Members of the B. pseudomallei Complex: B. mallei, B. pseudomallei, and B. thailandensis. [PDF]

PLoS ONE, 2016
The Burkholderia pseudomallei complex classically consisted of B. mallei, B. pseudomallei, and B. thailandensis, but has now expanded to include B. oklahomensis, B. humptydooensis, and three unassigned Burkholderia clades.
Chinn-Woan Lowe, Benjamin A Satterfield, Daniel B Nelson, Joseph D Thiriot, Michael J Heder, Jordon K March, David S Drake, Cynthia S Lew, Annette J Bunnell, Emily S Moore, Kim L O'Neill, Richard A Robison   +11 more
doaj   +1 more source

Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms. [PDF]

PLoS Computational Biology, 2015
Burkholderia pathogenicity relies on protein virulence factors to control and promote bacterial internalization, survival, and replication within eukaryotic host cells.
Vesna Memišević, Nela Zavaljevski, Seesandra V Rajagopala, Keehwan Kwon, Rembert Pieper, David DeShazer, Jaques Reifman, Anders Wallqvist   +7 more
doaj   +1 more source

ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei [PDF]

BMC Genomics, 2007
Abstract Background ATP binding cassette (ABC) systems are responsible for the import and export of a wide variety of molecules across cell membranes and comprise one of largest protein superfamilies found in prokarya, eukarya and archea. ABC systems play important roles in bacterial lifestyle, virulence and survival.
Harland, David N., Dassa, Elie, Titball, Richard W., Brown, Katherine A., Atkins, Helen S.   +4 more
openaire   +5 more sources

Preparation and transfer of Burkholderia mallei production strain 5584 in accordance with the biosafety requirements

Ветеринария сегодня, 2021
The Veterinary Service of the Russian Federation takes measures to ensure regular control of livestock health status, to prevent infectious diseases and their introduction into the country; and if such diseases are diagnosed, it takes measures to prevent
E. A. Artemeva, L. A. Melnikova, A. P. Rodionov   +2 more
doaj   +1 more source