Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders. [PDF]
PLoS ONE, 2015 Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both
Dina A Moustafa +7 more
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A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection. [PDF]
PLoS ONE, 2015 Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly infectious and broad-spectrum antibiotic resistant.
Beth A Bachert +11 more
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Current Advances in Burkholderia Vaccines Development
Cells, 2020 The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang +2 more
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Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis [PDF]
PLoS Neglected Tropical Diseases, 2019 Alfredo Torres +2 more
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Virulence, 2021 We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Guanbo Wang +6 more
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Pathogenesis ofBurkholderia pseudomalleiandBurkholderia mallei [PDF]
Military Medicine, 2009 Burkholderia pseudomallei and mallei are biological agents of military significance. There has been significant research in recent years to develop medical countermeasures for these organisms. This review summarizes work which details aspects of the pathogenesis of B.
Joseph C, Larsen, Nathan H, Johnson
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Evaluation of analytical-sensitivity and -specificity of a commercially available one-step real-time polymerase chain reaction assay kit for the detection of burkholderia mallei [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 Burkholderia mallei (B. mallei) is the etiological agent of glanders, a highly infectious and zoonotic disease of solipeds. Prompt and accurate detection of B. mallei and diagnosis of glanders is important for both, humans and animals.
KHAN I +9 more
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Ribotyping ofBurkholderia malleiisolates [PDF]
FEMS Immunology & Medical Microbiology, 2005 In this study, the subspecies differentiation of 25 isolates of Burkholderia mallei was attempted based on their ribotype polymorphisms. The isolates were from human and equine infections that occurred at various times around the world. DNA samples from each isolate were digested separately with PstI and EcoRI enzymes and probed with an Escherichia ...
Steven P, Harvey, Jennifer M, Minter
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A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Most Relevant Members of the B. pseudomallei Complex: B. mallei, B. pseudomallei, and B. thailandensis. [PDF]
PLoS ONE, 2016 The Burkholderia pseudomallei complex classically consisted of B. mallei, B. pseudomallei, and B. thailandensis, but has now expanded to include B. oklahomensis, B. humptydooensis, and three unassigned Burkholderia clades.
Chinn-Woan Lowe +11 more
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Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms. [PDF]
PLoS Computational Biology, 2015 Burkholderia pathogenicity relies on protein virulence factors to control and promote bacterial internalization, survival, and replication within eukaryotic host cells.
Vesna Memišević +7 more
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