Genetic diversity and spatial distribution of Burkholderia mallei by core genome-based multilocus sequence typing analysis. [PDF]
PLoS ONE, 2022 Burkholderia mallei is the etiological agent of glanders, a highly contagious and often fatal disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing assays are necessary to differentiate between individual strains. Here
Sandra Appelt +10 more
doaj +2 more sources
A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei [PDF]
BMC MicrobiologyBackground Glanders and melioidosis are contagious zoonotic diseases caused by Burkholderia mallei and B. pseudomallei, respectively. Bacterial isolation and polymerase chain reaction (PCR) have been used to detect these bacteria in animals suspected of ...
Mitsuru Nakase +15 more
doaj +2 more sources
Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health [PDF]
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani +2 more
wiley +2 more sources
Multiplex qPCR for reliable detection and differentiation of
BMC Infectious Diseases, 2013 Background Burkholderia mallei and B. pseudomallei are two closely related species of highly virulent bacteria that can be difficult to detect. Pathogenic Burkholderia are endemic in many regions worldwide and cases of infection, sometimes brought by ...
Janse Ingmar +3 more
doaj +4 more sources
The autotransporter protein BatA is a protective antigen against lethal aerosol infection with Burkholderia mallei and Burkholderia pseudomallei [PDF]
Vaccine: X, 2019 Background: Burkholderia mallei and Burkholderia pseudomallei are the causative agents of glanders and melioidosis, respectively. There is no vaccine to protect against these highly-pathogenic and intrinsically antibiotic-resistant bacteria, and there is
Eric R. Lafontaine +7 more
doaj +2 more sources
Development of Burkholderia mallei and pseudomallei vaccines [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 B. mallei and B. pseudomallei are Gram-negative bacteria that cause glanders and melioidosis, respectively. Inhalational infection with either organism can result in severe and rapidly fatal pneumonia.
Ediane Batista Silva, Steven eDow
doaj +3 more sources
Clinical repercussions of Glanders (Burkholderia mallei infection) in a Brazilian child: a case report [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2020 Glanders is a relatively unknown zoonotic disease caused by Burkholderia mallei. This bacterium affect solipeds and humans, and can be used as a biological warfare. Glanders is characterized as an occupational disease.
Eusébio Lino dos Santos Júnior +4 more
doaj +2 more sources
Use of a Safe, Reproducible, and Rapid Aerosol Delivery Method to Study Infection by Burkholderia pseudomallei and Burkholderia mallei in Mice [PDF]
PLoS ONE, 2013 Burkholderia pseudomallei, the etiologic agent of melioidosis, is a saprophytic bacterium readily isolated from wet soils of countries bordering the equator. Burkholderia mallei is a host-adapted clone of B.
Eric R Lafontaine +2 more
exaly +2 more sources
Use of the common marmoset to study Burkholderia mallei infection. [PDF]
PLoS ONE, 2015 Burkholderia mallei is a host-adapted bacterium that does not persist outside of its equine reservoir. The organism causes the zoonosis glanders, which is endemic in Asia, Africa, the Middle East and South America. Infection by B. mallei typically occurs
Tomislav Jelesijevic +9 more
doaj +2 more sources
An increase in intracellular p62/NBR1 and persistence of Burkholderia mallei and B. pseudomallei in infected mice linked to autophagy deficiency [PDF]
Immunity, Inflammation and Disease, 2019 Kamal U Saikh +2 more
exaly +2 more sources