Results 41 to 50 of about 2,546 (161)

DBSecSys 2.0: a database of Burkholderia mallei and Burkholderia pseudomallei secretion systems. [PDF]

BMC Bioinformatics, 2016
Abstract Background Burkholderia mallei and B. pseudomallei are the causative agents of glanders and melioidosis, respectively, diseases with high morbidity and mortality rates. B. mallei and B. pseudomallei are closely related genetically; B. mallei evolved from an ancestral strain of B. pseudomallei by genome reduction
Memišević V, Kumar K, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J.   +5 more
europepmc   +3 more sources

Antigenic Relatedness between Burkholderia pseudomallei and Burkholderia mallei [PDF]

Microbiology and Immunology, 2002
AbstractBurkholderia pseudomallei and Burkholderia mallei are causative agents of distinct diseases, namely, melioidosis and glanders, respectively. The two species are very closely related, based on DNA‐DNA homology, base sequence of the 16S rRNA, and phenotypic characteristics. Based on the use of polyclonal antisera, B. pseudomallei and B.
Narisara, Anuntagool, Stitaya, Sirisinha
openaire   +2 more sources

Thiotemplated Polyketide Chain Fusion and Reductive Cyclization Build the Reactive Butenolide Core of Malleicyprol

Angewandte Chemie, Volume 137, Issue 31, July 28, 2025.
Malleicyprol, a virulence factor of notorious animal and human pathogens of the Burkholderia pseudomallei (BP) group, results from the fusion of two individual polyketide chains. The noncanonical condensation domain of the PKS–NRPS hybrid synthetase BurF forms an ester bond, and the terminal reductase domain mediates a reductive chain release followed ...
Jonas Fiedler, Leo Dumjahn, Mie Ishida‐Ito, Felix Trottmann, Keishi Ishida, Christian Hertweck   +5 more
wiley   +2 more sources

Development of Real-Time Multiplex PCR Assay for the Detection and Differentiation of Burkholderia mallei and Burkholderia pseudomallei

Проблемы особо опасных инфекций, 2016
Objective of the study was to develop a real-time multiplex PCR assay for the detection and differentiation of B. mallei and B. pseudomallei, characterized by high sensitivity and specificity. Materials and Methods.
L. V. Lemasova, G. A. Tkachenko, S. S. Savchenko, O. S. Bondareva, V. A. Antonov   +4 more
doaj   +1 more source

Burkholderia Hep_Hag autotransporter (BuHA) proteins elicit a strong antibody response during experimental glanders but not human melioidosis

BMC Microbiology, 2007
Background The bacterial biothreat agents Burkholderia mallei and Burkholderia pseudomallei are the cause of glanders and melioidosis, respectively. Genomic and epidemiological studies have shown that B.
Foster Simon J, Clarke Simon R, Rengpipat Sirirat, Tumapa Sarinna, Holden Matthew TG, Tiyawisutsri Rachaneeporn, Nierman William C, Day Nicholas PJ, Peacock Sharon J   +8 more
doaj   +1 more source

Production of Monoclonal Antibodies against Outer Membrane Proteins of Burkholderia pseudomallei, Strain C-141

Проблемы особо опасных инфекций, 2008
Monoclonal antibodies (MAb) were produced against two B. pseudomallei high-purified membrane proteins with Mr 29 kDa (p29) and 45 kDa (p45). Monoclonal antibodies from culture supernatant fluids of 4F2 and 1G11 clones showed specific interaction with ...
S. S. Vetchinin, P. C. Kopylov, N. V. Kiseleva, A. M. Baranov, E. V. Baranova, E. V. Galkina, A. I. Borzilov, I. Y. Kalachev   +7 more
doaj   +1 more source

Hospital‐Based Cross‐Sectional Study of Burkholderia pseudomallei Seroreactivity Among Febrile Patients in Northernmost Vietnam: Near‐Neighbor Bloodstream Isolates, Environmental Correlates, and Spatial Clustering

GeoHealth, Volume 10, Issue 6, June 2026.
Abstract Melioidosis is a potentially fatal tropical disease caused by the environmentally mediated bacterium, Burkholderia pseudomallei. In Vietnam, melioidosis is not nationally reportable and little is known regarding its epidemiology and distribution in the northernmost mountainous provinces.
Morgan C. Metrailer, Tran Thi Le Quyen, Khang Van Pham, Tan Minh Luong, Treenate Jiranantasak, Andrew P. Bluhm, Frank J. Tuozzo II, Thi Thu Ha Hoang, Minh Hoa Luong, Bich Ngoc Do, Thanh Hai Pham, Madison E. A. Harman, Michael H. Norris, Trinh Thanh Trung, Jason K. Blackburn   +14 more
wiley   +1 more source

PCR-RFLP based differentiation of Burkholderia mallei and Burkholderia pseudomallei

Molecular and Cellular Probes, 2004
Burkholderia mallei and Burkholderia pseudomallei manifest a high similarity with regard to clinical syndromes, glanders and melioidosis. Phenotypic and genotypic characters are also highly similar. In an attempt to differentiate the two organisms, the molecular method was applied. This study aimed to identify the different DNA fragment in B.
Suda, Tanpiboonsak, Atchara, Paemanee, Sasinee, Bunyarataphan, Sumalee, Tungpradabkul   +3 more
openaire   +2 more sources

In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing.

PLoS Neglected Tropical Diseases, 2022
Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B.
Heather P McLaughlin, Christopher A Gulvik, David Sue   +2 more
doaj   +1 more source

Micro/nanorobots for detecting and eliminating biological and chemical warfare agents

BMEMat, Volume 4, Issue 1, March 2026.
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li, Huaijuan Zhou, Di Shi, Zdeněk Sofer, Jinhua Li   +4 more
wiley   +1 more source