Oropharyngeal Aspiration of Burkholderia mallei and Burkholderia pseudomallei in BALB/c Mice [PDF]
PLoS ONE, 2014 Burkholderia mallei and Burkholderia pseudomallei are potentially lethal pathogens categorized as biothreat agents due, in part, to their ability to be disseminated via aerosol.
Kevin Schully
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A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei [PDF]
BMC MicrobiologyBackground Glanders and melioidosis are contagious zoonotic diseases caused by Burkholderia mallei and B. pseudomallei, respectively. Bacterial isolation and polymerase chain reaction (PCR) have been used to detect these bacteria in animals suspected of ...
Mitsuru Nakase +15 more
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Multiplex qPCR for reliable detection and differentiation of
BMC Infectious Diseases, 2013 Background Burkholderia mallei and B. pseudomallei are two closely related species of highly virulent bacteria that can be difficult to detect. Pathogenic Burkholderia are endemic in many regions worldwide and cases of infection, sometimes brought by ...
Janse Ingmar +3 more
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Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health. [PDF]
Vet Med SciThis review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Kanani Y, Oryan A, Derakhshandeh A.
europepmc +2 more sources
The autotransporter protein BatA is a protective antigen against lethal aerosol infection with Burkholderia mallei and Burkholderia pseudomallei [PDF]
Vaccine: X, 2019 Background: Burkholderia mallei and Burkholderia pseudomallei are the causative agents of glanders and melioidosis, respectively. There is no vaccine to protect against these highly-pathogenic and intrinsically antibiotic-resistant bacteria, and there is
Eric R. Lafontaine +7 more
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Development of Burkholderia mallei and pseudomallei vaccines [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 B. mallei and B. pseudomallei are Gram-negative bacteria that cause glanders and melioidosis, respectively. Inhalational infection with either organism can result in severe and rapidly fatal pneumonia.
Ediane Batista Silva, Steven eDow
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Clinical repercussions of Glanders (Burkholderia mallei infection) in a Brazilian child: a case report [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2020 Glanders is a relatively unknown zoonotic disease caused by Burkholderia mallei. This bacterium affect solipeds and humans, and can be used as a biological warfare. Glanders is characterized as an occupational disease.
Eusébio Lino dos Santos Júnior +4 more
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Use of a Safe, Reproducible, and Rapid Aerosol Delivery Method to Study Infection by Burkholderia pseudomallei and Burkholderia mallei in Mice [PDF]
PLoS ONE, 2013 Burkholderia pseudomallei, the etiologic agent of melioidosis, is a saprophytic bacterium readily isolated from wet soils of countries bordering the equator. Burkholderia mallei is a host-adapted clone of B.
Robert Hogan +2 more
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Use of the common marmoset to study Burkholderia mallei infection. [PDF]
PLoS ONE, 2015 Burkholderia mallei is a host-adapted bacterium that does not persist outside of its equine reservoir. The organism causes the zoonosis glanders, which is endemic in Asia, Africa, the Middle East and South America. Infection by B. mallei typically occurs
Tomislav Jelesijevic +9 more
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Innate immune response to Burkholderia mallei. [PDF]
Curr Opin Infect Dis, 2017 Purpose of review Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen is considered a potential biological threat ...
Saikh KU, Mott TM.
europepmc +4 more sources