Results 91 to 100 of about 22,717 (216)

Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
T3SS is a dedicated machinery that mediates interactions between bacteria and eukaryotic cells, providing a functional interface in pathogenic or symbiotic associations. Phylogenetic analyses and T3SS‐gene synteny revealed nine gene clusters, with no needle protein gene (sctF). However, an orphan CDS encoding a putative SctF was found.
Gabrielle Tomé Cordeiro, Hadassa Loth de Oliveira, Danielly C. O. Mariano, Yasmin Salazar Torres, Graciela Maria Dias, Bianca C. Neves   +5 more
wiley   +1 more source

Development of ceftazidime resistance in an acute Burkholderia pseudomallei infection. [PDF]

, 2012
Burkholderia pseudomallei, a bacterium that causes the disease melioidosis, is intrinsically resistant to many antibiotics. First-line antibiotic therapy for treating melioidosis is usually the synthetic β-lactam, ceftazidime (CAZ), as almost all B ...
Cook, James M, Keim, Paul, Limmathurotsakul, Direk, Peacock, Sharon J, Pearson, Talima, Price, Erin P, Sarovich, Derek S, Von Schulze, Alex T, Wolken, Spenser R   +8 more
core   +1 more source

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence‐Associated Properties

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki, Sara B. Papp, Bayley Polk, Sean Jeffreys, Megan P. Tompkins, Anwar A. Kalalah, Mark Eppinger, Guoquan Zhang, M. N. Guentzel, James P. Chambers, Bernard P. Arulanandam, Jieh‐Juen Yu   +11 more
wiley   +1 more source

Burkholderia pseudomallei transcriptional adaptation in macrophages [PDF]

BMC Genomics, 2012
Abstract Background Burkholderia pseudomallei is a facultative intracellular pathogen of phagocytic and non-phagocytic cells. How the bacterium interacts with host macrophage cells is still not well understood and is critical to appreciate the strategies used by this bacterium to survive and how ...
Sylvia Chieng, Laura Carreto, Sheila Nathan   +2 more
openaire   +4 more sources

Structural and functional characterization of a metagenomically derived γ‐type carbonic anhydrase and its engineering into a hyperthermostable esterase

Protein Science, Volume 34, Issue 12, December 2025.
Abstract The 16S microbial community profiling of a metagenomics library from geothermal spring at Lisvori (Lesvos island, Greece) enabled the identification of a putative sequence exhibiting 95% identity to the γ‐type carbonic anhydrase (γ‐CA) from Caloramator australicus (γ‐CaCA).
Charoutioun S. Bodourian, Mohsin Imran, Nikolaos D. Georgakis, Anastassios C. Papageorgiou, Nikolaos E. Labrou   +4 more
wiley   +1 more source

Survival of Burkholderia pseudomallei in Water [PDF]

BMC Research Notes, 2008
AbstractBackgroundThe ability ofBurkholderia pseudomalleito survive in water likely contributes to its environmental persistence in endemic regions. To determine the physiological adaptations which allowB. pseudomalleito survive in aqueous environments, we performed microarray analyses ofB.
Woods Donald E, Tuanyok Apichai, Moore Richard A   +2 more
openaire   +3 more sources

Melioidosis presenting as a mycotic aneurysm in a Korean patient, diagnosed by 16S rRNA sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

International Journal of Infectious Diseases, 2015
A case of melioidosis with a mycotic aneurysm is reported. The blood and tissue isolates were identified as three different species of Burkholderia using the automated identification systems, VITEK 2 and matrix-assisted laser desorption/ionization time ...
Hee Ryeong Jang, Chung Won Lee, Soon Jung Ok, Min Ji Kim, Mi Ju Bae, Seunghwan Song, Jongyoun Yi, Kye-Hyung Kim   +7 more
doaj   +1 more source

The pathogen Pseudomonas aeruginosa negatively affects the attraction response of the nematode Caenorhabditis elegans to bacteria.

, 2006
The nematode Caenorhabditis elegans has previously been used to identify virulence mechanisms of bacteria and to characterise host responses to infection. In this study, we have developed an assay to measure C.
Atkins, Helen S, Atkins, Timothy P, Laws, Thomas R, Titball, Richard W   +3 more
core   +1 more source

Hotspots of Bacterial Pathogen Abundance and Exposure Risk in Soils of the Contiguous United States

GeoHealth, Volume 9, Issue 12, December 2025.
Abstract Soils are reservoirs of pathogenic bacteria that cause human illness, particularly after mobilizing events such as extreme rain. Land‐use patterns (e.g., proximity to agriculture) and soil properties (e.g., moisture) are associated with abundance of individual pathogenic bacteria. However, there are major uncertainties in (a) the importance of
Emily A. Matthews, Ying‐Xian Goh, Shannon L. Hepp, Jingqiu Liao, Ryan S. D. Calder   +4 more
wiley   +1 more source

Pathogenesis ofBurkholderia pseudomalleiandBurkholderia mallei [PDF]

Military Medicine, 2009
Burkholderia pseudomallei and mallei are biological agents of military significance. There has been significant research in recent years to develop medical countermeasures for these organisms. This review summarizes work which details aspects of the pathogenesis of B.
Joseph C, Larsen, Nathan H, Johnson
openaire   +2 more sources