Results 41 to 50 of about 22,717 (216)

Characterization of Burkholderia pseudomallei and Burkholderia pseudomallei-like strains

Epidemiology and Infection, 1997
Previous reports in the literature suggest that Burkholderia pseudomallei strains can be differentiated on the basis of animal virulence. Twenty environmentally and clinically derived isolates of Burkholderia pseudomallei were examined for the production of exoenzymes, morphological and biochemical phenotypes and virulence for Syrian ...
P J, Brett, D, Deshazer, D E, Woods
openaire   +3 more sources

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler, Ingrid Richter, Katharina Dornblut, Alicia Scharf, Christian Hertweck   +4 more
wiley   +2 more sources

An unusual case of primary melioidotic prostatic abscess complicated by perianal abscess

IDCases, 2018
Burkholderia pseudomallei is recognized to cause severe and fatal infections. Most of the infections caused by this facultative intracellular gram-negative bacterium are pneumonia, soft tissue, genito-urinary and central nervous system infection.
Y.C. Chee, Y.N. Chee
doaj   +1 more source

Development of a prototype Lateral Flow Immunoassay (LFI) for the rapid diagnosis of melioidosis [PDF]

, 2014
Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. Isolation of B. pseudomallei from clinical samples is the “gold standard” for the diagnosis of melioidosis; results can take 3–7 days to ...
AuCoin, David, Brett, Paul, Burtnick, Mary, Chantratita, Narisara, Chen, Hongjing, Currie, Bart J., Dillon, Michael, Duval, Brea, Hoffmaster, Alex, Houghton, Raymond, Hubbard, Mark, Limmathurotsakul, Direk, Mayo, Mark J., Peacock, Sharon, Reed, Dana, Sarovich, Derek S., Theobald, Vanessa, Wongsuvan, Gumphol   +17 more
core   +3 more sources

Efflux Pump-mediated Drug Resistance in Burkholderia

Frontiers in Microbiology, 2015
Several members of the genus Burkholderia are prominent pathogens. Infections caused by these bacteria are difficult to treat because of significant antibiotic resistance.
Nicole L Podnecky, Katherine A Rhodes, Katherine A Rhodes, Herbert P Schweizer, Herbert P Schweizer   +4 more
doaj   +1 more source

Diverse Burkholderia Species Isolated from Soils in the Southern United States with No Evidence of B. pseudomallei. [PDF]

PLoS ONE, 2015
The global distribution of the soil-dwelling bacterium Burkholderia pseudomallei, causative agent of melioidosis, is poorly understood. We used established culturing methods developed for B.
Carina M Hall, Joseph D Busch, Kenzie Shippy, Christopher J Allender, Mirjam Kaestli, Mark Mayo, Jason W Sahl, James M Schupp, Rebecca E Colman, Paul Keim, Bart J Currie, David M Wagner   +11 more
doaj   +1 more source

Burkholderia pseudomallei

Trends in Microbiology
Burkholderia pseudomallei is a Gram negative, facultative intracellular bacterium that resides in the rhizosphere of tropical soils. B. pseudomallei causes melioidosis, which is transmitted by cutaneous entry, ingestion, or inhalation of contaminated soil or water. Infection with B.
Erica D. Phillips, Erin C. Garcia
openaire   +2 more sources

Transcriptional profiles of Burkholderia pseudomallei reveal the direct and indirect roles of Sigma E under oxidative stress conditions [PDF]

, 2016
This is the final version of the article. Available from BioMed Central via the DOI in this record.BACKGROUND: Burkholderia pseudomallei, the causative agent of melioidosis, is a Gram-negative bacterium widely distributed in soil and water in endemic ...
Hemsley, CM, Jitprasutwit, S, Juntawieng, N, Korbsrisate, S, Ong, C, Ooi, WF, Tan, P, Titball, RW, Vattanaviboon, P   +8 more
core   +1 more source

Pathogenicity and virulence ofBurkholderia pseudomallei

Virulence, 2022
The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by either inhalation or inoculation can lead to severe disease. B. pseudomallei rapidly shifts from an environmental organism to an aggressive intracellular pathogen capable of ...
Nicole M. Bzdyl, Clare L. Moran, Justine Bendo, Mitali Sarkar-Tyson   +3 more
openaire   +3 more sources

The in vitro tolerant persister population in Burkholderia pseudomallei is altered by environmental factors

Frontiers in Microbiology, 2015
Bacterial persistence due to antibiotic tolerance is a critical aspect of antibiotic treatment failure, disease latency, and chronic or reemergent infections.
William Charles Nierman, Liliana eLosada, Yan eYu   +2 more
doaj   +1 more source