Results 51 to 60 of about 25,113 (239)

Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei [PDF]

, 2011
Burkholderia pseudomallei is the etiological agent of melioidosis. Because of the bacterium’s intrinsic resistance and propensity to establish latent infections, melioidosis therapy is complicated and prolonged. Newer generation b-lactams, specifically
Drew A Rholl, Krisztina M Papp-Wallace, Andrew P Tomaras, Michael L Vasil, Robert A Bonomo, Robert A Bonomo, Herbert P Schweizer   +6 more
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The in vitro tolerant persister population in Burkholderia pseudomallei is altered by environmental factors

Frontiers in Microbiology, 2015
Bacterial persistence due to antibiotic tolerance is a critical aspect of antibiotic treatment failure, disease latency, and chronic or reemergent infections.
William Charles Nierman, Liliana eLosada, Yan eYu   +2 more
doaj   +1 more source

A multi-country study using MALDI-TOF mass spectrometry for rapid identification of Burkholderia pseudomallei

BMC Microbiology, 2021
Background Burkholderia pseudomallei is the bacterial causative agent of melioidosis, a difficult disease to diagnose clinically with high mortality if not appropriately treated. Definitive diagnosis requires isolation and identification of the organism.
Wanitda Watthanaworawit, Tamalee Roberts, Jill Hopkins, Ian Gassiep, Robert Norton, Matthew T. Robinson, Joy Silisouk, Poda Sar, Sena Sao, Premjit Amornchai, Direk Limmathurotsakul, Vanaporn Wuthiekanun, Francois Nosten, Andrew J. H. Simpson, Paul Turner, Clare L. Ling   +15 more
doaj   +1 more source

Molecular phylogeny of Burkholderia pseudomallei

Acta Tropica, 2000
In terms of population structure, the species Burkholderia pseudomallei contains both clonal and non-clonal elements. By indexing variation in rRNA loci using the restriction endonuclease BamHI, we found that two ribotypes (types 1 and 3) are predominant in nature. Ribotype 3 is prevalent in Asian countries while ribotype 1 is more widespread.
Pitt, T, Trakulsomboon, S, Dance, D
openaire   +2 more sources

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the identification of Burkholderia pseudomallei from Asia and Australia and differentiation between Burkholderia species.

PLoS ONE, 2017
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is increasingly used for rapid bacterial identification. Studies of Burkholderia pseudomallei identification have involved small isolate numbers drawn from a ...
Vichaya Suttisunhakul, Apinya Pumpuang, Peeraya Ekchariyawat, Vanaporn Wuthiekanun, Mindy G Elrod, Paul Turner, Bart J Currie, Rattanaphone Phetsouvanh, David A B Dance, Direk Limmathurotsakul, Sharon J Peacock, Narisara Chantratita   +11 more
doaj   +1 more source

BIOFILMS OF PATHOGENIC BURKHOLDERIA AND THEIR ROLE IN RESISTANCE TO ANTIBIOTICS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
The review contains the current knowledge on the main issues of Burkholderia pseudomallei and Burkholderia mallei biofilm formation. The role ofknown structural elements of Burkholderia cells (flagella, type IV pili, LPS), as well as autotransporter ...
E. V. Shubnikova, L. K. Merinova, T. V. Senina, E. V. Korol, O. A. Merinova   +4 more
doaj   +1 more source

Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei. [PDF]

, 2017
Melioidosis, caused by Burkholderia pseudomallei, is endemic in northeastern Thailand and Northern Australia. Severe septicemic melioidosis is associated with high levels of pro-inflammatory cytokines and is correlated with poor clinical outcomes.
A Easton, A Haque, A Novikov, A O’Garra, AC Cheng, AJ Simpson, BJ Currie, C Kewcharoenwong, CA Rowland, CR Romero, D Limmathurotsakul, D Limmathurotsakul, D Limmathurotsakul, D Suwannasaen, FN Lauw, G Lertmemongkolchai, GC Koo, GC Ulett, GC Ulett, GCKW Koh, GCKW Koh, J Chen, J Morris, J-X See, JM Pitt, JR Teijaro, JU Igietseme, K Breitbach, KA Hodgson, KN Couper, KS Tan, KW Moore, L Conejero, M Kortylewski, M Saraiva, MJ Greenberger, MM Kane, MP Moutschen, MTG Holden, N Chantratita, N White, P Saengmuang, P Santanirand, P Tippayawat, P Trzonkowski, PS Redford, R Sabat, S Chanchamroen, SA Dalrymple, TAF Weehuizen, V Wuthiekanun, W Aekplakorn, WJ Wiersinga, Y Homma, Y Suputtamongkol   +54 more
core   +1 more source

PCR-based identification of Burkholderia pseudomallei [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2006
DNA amplification techniques are being used increasingly in clinical laboratories to confirm the identity of medically important bacteria. A PCR-based identification method has been in use in our centre for 10 years for Burkholderia pseudomallei and was used to confirm the identity of bacteria isolated from cases of melioidosis in Ceará since 2003 ...
Merritt, Adam, Inglis, Timothy J.J., Chidlow, Glenys, Harnett, Gerry   +3 more
openaire   +4 more sources

Melioidosis: Case reports of confirmed Burkholderia pseudomallei in Saudi Arabia

Journal of Infection and Public Health, 2020
Melioidosis is an infectious disease of tropical climates. The disease is caused by the bacterium Burkholderia pseudomallei. Most cases are diagnosed in southeast Asia and northern Australia. Some imported cases diagnosed in returning tourists, soldiers,
H. Alhatmi, A. Alharbi, M. Bosaeed, O. Aldosary, S. Aljohani, B. Alalwan, A. Alsaeedi, S. Almahmoud, A. Alothman   +8 more
doaj   +1 more source

Identification and characterisation of toxin-antitoxin systems (TA) in Burkholderia pseudomallei [PDF]

, 2013
The aim of this study was to identify and characterise type II toxin-antitoxin (TA) systems in Burkholderia pseudomallei, the causative agent of the human disease melioidosis. 8 putative TA systems were identified within the genome of B. pseudomallei
Butt, Aaron Trevor
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