Further engineering of R. toruloides for the production of terpenes from lignocellulosic biomass [PDF]
Background Mitigation of climate change requires that new routes for the production of fuels and chemicals be as oil-independent as possible. The microbial conversion of lignocellulosic feedstocks into terpene-based biofuels and bioproducts represents ...
James Kirby +21 more
doaj +2 more sources
Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity [PDF]
Coronaviruses (CoV) emerge suddenly from animal reservoirs to cause novel diseases in new hosts. Discovered in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in camels in the Middle East and is continually causing local ...
Amy C. Sims +21 more
doaj +2 more sources
Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution [PDF]
Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics and ...
Paul D. Piehowski +13 more
doaj +2 more sources
Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics [PDF]
Tsai, Zhang, Scholten et al. develop a surfactant- assisted one-pot sample preparation coupled with mass spectrometry method (SOP-MS) for label-free global single-cell proteomics. This method allows researchers to measure hundreds of proteins from single
Chia-Feng Tsai +27 more
doaj +2 more sources
Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis [PDF]
Background Lipids are regulators of insulitis and β-cell death in type 1 diabetes development, but the underlying mechanisms are poorly understood. Here, we investigated how the islet lipid composition and downstream signaling regulate β-cell death ...
Soumyadeep Sarkar +24 more
doaj +2 more sources
A compendium of multi-omics data illuminating host responses to lethal human virus infections [PDF]
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death.
Amie J. Eisfeld +28 more
doaj +2 more sources
Octavian’s footprints: hillforts, camps and roads between Burnum and Sinotium
On the basis of a recent field survey of Petrovo polje, in comparison to the data of Appian and Dio Cassius, the Octavian war campaign against the Dalamatae in the area between Burnum and Sinotion (Synodium, Synodion, Sinotium) is reconsidered.
Silvia Bekavac, Ž. Miletić
semanticscholar +1 more source
Usefulness of uroflowmetry for the management of urethral prolapse in a prepubertal girl
Background: Urethral prolapse is defined as the eversion of the urethral mucosa at the level of the urethral meatus. It commonly presents as a vulvar mass, followed by bleeding and dysuria.
Daisuke Matsumoto +10 more
doaj +1 more source
Abstract The article presents the results of archaeological prospection of site Dračevica (Donji Radišići, Ljubuški municipality, West Herzegovina Canton, Bosnia and Herzegovina) which was partly excavated in the late 19th century and so far has been interpreted as a Roman villa, possibly with a special function (road station) and a name attested in ...
Tomasz Dziurdzik +3 more
wiley +1 more source
New insights about the previously unpublished inscription of cohors III Alpinorum, located in the Archaeological Museum in Zadar, are brought to light. Previously documented as an inscription from an unknown site, calling upon the diaries of a Friar Lujo
Nikola Cesarik, Luka Drahotusky-Bruketa
doaj +1 more source

