Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity [PDF]
mSphereCoronaviruses (CoV) emerge suddenly from animal reservoirs to cause novel diseases in new hosts. Discovered in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in camels in the Middle East and is continually causing local ...
Amy C. Sims +21 more
doaj +2 more sources
Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution [PDF]
Nature Communications, 2020 Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics and ...
Paul D. Piehowski +13 more
doaj +2 more sources
Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics [PDF]
Communications Biology, 2021 Tsai, Zhang, Scholten et al. develop a surfactant- assisted one-pot sample preparation coupled with mass spectrometry method (SOP-MS) for label-free global single-cell proteomics. This method allows researchers to measure hundreds of proteins from single
Chia-Feng Tsai +27 more
doaj +2 more sources
Production of ent-kaurene from lignocellulosic hydrolysate in Rhodosporidium toruloides [PDF]
Microbial Cell Factories, 2020 Background Rhodosporidium toruloides has emerged as a promising host for the production of bioproducts from lignocellulose, in part due to its ability to grow on lignocellulosic feedstocks, tolerate growth inhibitors, and co-utilize sugars and lignin ...
Gina M. Geiselman +15 more
doaj +2 more sources
Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis [PDF]
Cell Communication and SignalingBackground Lipids are regulators of insulitis and β-cell death in type 1 diabetes development, but the underlying mechanisms are poorly understood. Here, we investigated how the islet lipid composition and downstream signaling regulate β-cell death ...
Soumyadeep Sarkar +24 more
doaj +2 more sources
A compendium of multi-omics data illuminating host responses to lethal human virus infections [PDF]
Scientific DataHuman infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death.
Amie J. Eisfeld +28 more
doaj +2 more sources
Burnum, rimska vojska i Jupiterov kult
Godišnjak Titius : godišnjak za interdisciplinarna istraživanja porječja Krke, 2009 Burnum è uno delle più importanti antiche ubicazioni archeologiche sul territorio di odierna Bukovica. Si trova alla costa destra della fi ume Cherca in villaggio Ivoševci vicino a Kistanje. Si tratta del romano accampamento di legione che si trova di fronte al importante ruderi vicino al villaggio Puljani, in luogho dove esisteva il passaggio ...
Marko Sinobad
openaire +4 more sources
Spätrepublikanische und augusteische Militaria aus Burnum
, 2019 Wiederholt wurde der Versuch unternommen, einen dauerhaften Aufenthalt des römischen Militärs im Illyricum bereits in spätrepublikanischer bzw. frühaugusteischer Zeit nachzuweisen. Dieser wurde mit dem Vorstoß des Caius Octavianus 35–33 vor Chr., dem bellum Pannonicum des Tiberius 12– 10 vor Chr., oder dem bellum Batonianum 6–9 nach Chr.
Tončinić, Domagoj +2 more
+4 more sources
Usefulness of uroflowmetry for the management of urethral prolapse in a prepubertal girl
Journal of Pediatric Surgery Case Reports, 2023 Background: Urethral prolapse is defined as the eversion of the urethral mucosa at the level of the urethral meatus. It commonly presents as a vulvar mass, followed by bleeding and dysuria.
Daisuke Matsumoto +10 more
doaj +1 more source