Mycolactone Diffuses into the Peripheral Blood of Buruli Ulcer Patients - Implications for Diagnosis and Disease Monitoring. [PDF]
BACKGROUND: Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis ...
Le Chevalier, Fabien +53 more
core +2 more sources
Providing insight into the incubation period of Mycobacterium ulcerans disease: two case reports
Background Buruli ulcer caused by Mycobacterium ulcerans is endemic in parts of West Africa and is most prevalent among the 5–15 years age group; Buruli ulcer is uncommon among neonates.
Y. A. Amoako +13 more
doaj +1 more source
Metagenomics Comparison of Buruli and Non Buruli Ulcer Skin Wound [PDF]
Introduction: Buruli Ulcer (BU) is caused due to mycobacteria, namely Mycobacterium ulcerans. Buruli ulcer is caused by the mycolactones that are secreted by the Mycobacterium ulcerans which results into the tissue necrosis.
Anushka Singh, Ruchi Yadav
doaj +1 more source
AbstractBuruli ulcer (BU), or Mycobacterium ulcerans infection, is a new emerging infectious disease which has been reported in over 33 countries worldwide. It has been noted not only in tropical areas, such as West Africa where it is most endemic, but also in moderate non‐tropical climate areas, including Australia and Japan.
Rie R, Yotsu +6 more
openaire +2 more sources
Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics. [PDF]
A specific and sensitive serodiagnostic test for Mycobacterium ulcerans infection would greatly assist the diagnosis of Buruli ulcer and would also facilitate seroepidemiological surveys. By comparative genomics, we identified 45 potential M.
Sacha J Pidot +13 more
doaj +1 more source
Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer. [PDF]
Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model.
Junichiro En +6 more
doaj +1 more source
Illness meanings and experiences for pre-ulcer and ulcer conditions of Buruli ulcer in the Ga-West and Ga-South municipalities of Ghana [PDF]
: BACKGROUND: Ghana is a Buruli ulcer (BU) endemic country yet there is paucity of socio-cultural research on BU. Examining distinctive experiences and meanings for pre-ulcers and ulcers of BU may clarify the disease burden, illness experience and local ...
Kwakye-Maclean Cynthia +21 more
core +2 more sources
BackgroundBuruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans, an environmental mycobacterium. Although transmission of M. ulcerans remains poorly understood, the main identified risk factor for acquiring Buruli ulcer is living ...
Ronald Gnimavo +9 more
doaj +1 more source
Mycobacterium ulcerans persistence at a village water source of Buruli ulcer patients [PDF]
Buruli ulcer (BU), a neglected tropical disease of the skin and subcutaneous tissue, is caused by Mycobacterium ulcerans and is the third most common mycobacterial disease after tuberculosis and leprosy.
Nadia Schürch (383786) +69 more
core +2 more sources
Buruli ulcer: Rare presentation of a chronic nonhealing ulcer in India
Buruli ulcer is a rare disabling skin infection caused by Mycobacterium ulcerans. It is essential to consider Buruli ulcer as one of the possible differential diagnoses for a chronic nonhealing ulcer and treat the wounds with antitubercular therapy for ...
Ajith John George +3 more
doaj +1 more source

