Results 1 to 10 of about 3,659 (110)

PPE Barcoding Identifies Biclonal Mycobacterium ulcerans Buruli Ulcer, Côte d’Ivoire [PDF]

Microbiology Spectrum, 2023
Mycobacterium ulcerans, an environmental opportunistic pathogen, causes necrotic cutaneous and subcutaneous lesions, named Buruli ulcers, in tropical countries. PCR-derived tests used to detect M.
B. G. O. Tchan, S. Ngazoa-Kakou, N. Aka, N. K. B. Apia, N. Hammoudi, M. Drancourt, J. Saad   +6 more
doaj   +2 more sources

Detection of Mycobacterium ulcerans with IS2404 loop-mediated isothermal amplification and a fluorescent reporter probe [PDF]

Applied and Environmental Microbiology
An exquisitely sensitive quantitative PCR (qPCR) assay targeting the high-copy number insertion sequence, IS2404, is the gold standard diagnostic test for Mycobacterium ulcerans, the agent of the neglected tropical skin disease Buruli ulcer.
Jean Y. H. Lee, Jessica L. Porter, Maria Globan, Caroline J. Lavender, Yinhua Zhang, Nathan A. Tanner, Emma C. Hobbs, Andrew H. Buultjens, Timothy P. Stinear   +8 more
doaj   +2 more sources

Profiling Mycobacterium ulcerans: sporulation, survival strategy and response to environmental factors [PDF]

Future Science OA, 2023
Mycobacterium ulcerans is the causative agent of Buruli ulcer – a necrotizing skin infection. As an environmental pathogen, it has developed stress response mechanisms for survival. Similar to endospore formation in M.
Eunice Ampadubea Ayerakwa, Molly Kukua Abban, Abiola Isawumi, Lydia Mosi   +3 more
doaj   +2 more sources

Improved protocols for isolation of Mycobacterium ulcerans from clinical samples [PDF]

BMC Microbiology
Background The isolation and culture of Mycobacterium ulcerans (Mu) as a primary diagnostic modality for Buruli ulcer (BU) disease are limiting due to their low sensitivity and slow-growing nature. M.
Bernadette Agbavor, Rejoice Agyeiwaa Arthur, Abigail Agbanyo, Dzifa Kofi Ahiatrogah, Charity Wiafe Akenten, Cynthia Adu-Asiamah, Kabiru Mohammed Abass, Elizabeth Ofori, George Amofa, Kwadwo Boampong, Thorsten Thye, Denise Dekker, Mathew Glover Addo, Mark Wansbrough-Jones, Tim John Bull, Yaw Ampem Amoako, Richard Odame Phillips   +16 more
doaj   +2 more sources

Mycobacterium ulcerans in Possum Feces before Emergence in Humans, Australia [PDF]

Emerging Infectious Diseases
We describe emergence of Buruli ulcer in urban Geelong, Victoria, Australia, and examine timing and proximity of human cases to detection of Mycobacterium ulcerans DNA in possum feces. M.
Bridgette J. McNamara, Jack Cornish, Kim R. Blasdell, Eugene Athan, Naomi E. Clarke, Tiffany Pe, Mohammad Akhtar Hussain, Michael Muleme, Ee Laine Tay, Michael Dunn, Victoria Boyd, Anjana Karawita, Daniel P. O’Brien   +12 more
doaj   +2 more sources

A rapid and simple MALDI-TOF MS lipid profiling method for differentiating Mycobacterium ulcerans from Mycobacterium marinum [PDF]

Journal of Clinical Microbiology
Mycobacterium ulcerans, a slow-growing nontuberculous mycobacterium, causes Buruli ulcer, a neglected tropical disease. Distinguishing M. ulcerans from related species, including Mycobacterium marinum, poses challenges with respect to making accurate ...
Takeshi Komine, Hanako Fukano, Mitsunori Yoshida, Yuji Miyamoto, Makoto Nakaya, Azumi Fujinaga, Kohei Doke, Yoshihiko Hoshino   +7 more
doaj   +2 more sources

Mosquitoes as Vectors of Mycobacterium ulcerans Based on Analysis of Notifications of Alphavirus Infection and Buruli Ulcer, Victoria, Australia [PDF]

Emerging Infectious Diseases
Alphavirus infections are transmitted by mosquitoes, but the mode of transmission for Mycobacterium ulcerans, which causes Buruli ulcer, is contested. Using notification data for Victoria, Australia, during 2017–2022, adjusted for incubation period, we ...
Andrew H. Buultjens, Ee Laine Tay, Aidan Yuen, N. Deborah Friedman, Timothy P. Stinear, Paul D.R. Johnson   +5 more
doaj   +2 more sources

A Mycobacterium ulcerans vaccine pilot trial using an accurate low-dose challenge [PDF]

Microbiology Spectrum
A Mycobacterium ulcerans human challenge model has the potential to fundamentally advance our understanding of early human immune responses to infection, while rapidly evaluating vaccines and other therapeutic interventions.
Stephen Muhi, Jessica L. Porter, Timothy P. Stinear   +2 more
doaj   +2 more sources

Environmental risk factors associated with the presence of Mycobacterium ulcerans in Victoria, Australia. [PDF]

PLoS ONE, 2022
In recent years reported cases of Buruli ulcer, caused by Mycobacterium ulcerans, have increased substantially in Victoria, Australia, with the epidemic also expanding geographically. To develop an understanding of how M.
Kim R Blasdell, Bridgette McNamara, Daniel P O'Brien, Mary Tachedjian, Victoria Boyd, Michael Dunn, Peter T Mee, Simone Clayton, Julie Gaburro, Ina Smith, Katherine B Gibney, Ee Laine Tay, Emma C Hobbs, Nilakshi Waidyatillake, Stacey E Lynch, Timothy P Stinear, Eugene Athan   +16 more
doaj   +2 more sources

Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model. [PDF]

PLoS Neglected Tropical Diseases
Critical scientific questions remain regarding infection with Mycobacterium ulcerans, the organism responsible for the neglected tropical disease, Buruli ulcer (BU).
Stephen Muhi, Andrew H Buultjens, Jessica L Porter, Julia L Marshall, Marcel Doerflinger, Sacha J Pidot, Daniel P O'Brien, Paul D R Johnson, Caroline J Lavender, Maria Globan, James McCarthy, Joshua Osowicki, Timothy P Stinear   +12 more
doaj   +2 more sources