Results 41 to 50 of about 123,926 (204)

Evolution of two distinct phylogenetic lineages of the emerging human pathogen Mycobacterium ulcerans

BMC Evolutionary Biology, 2007
Background Comparative genomics has greatly improved our understanding of the evolution of pathogenic mycobacteria such as Mycobacterium tuberculosis.
Portaels Francoise, Stinear Tim, Naegeli Martin, Rondini Simona, Käser Michael, Certa Ulrich, Pluschke Gerd   +6 more
doaj   +1 more source

Vaccination with the surface proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans induces antibodies but fails to provide protection against Buruli ulcer [PDF]

, 2016
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African countries. M.
Miriam Bolz, Gerd Pluschke, Wulf Oehlmann, Malcolm S Duthie, Dreyer, Anita M., Sarah Kerber, Malcolm S. Duthie (231822), Duthie, Malcolm S., Andrea Vettiger, Wulf Oehlmann (332809), Mahavir Singh, Singh, Mahavir, Sarah Kerber (421868), Mahavir Singh (70735), Oehlmann, Wulf, Anita M. Dreyer (2154052), Andrea Vettiger (436255), Kerber, Sarah, Bolz, Miriam, Miriam Bolz (309717), Vettiger, Andrea, Angèle Bénard (238312), Bénard, Angèle, Anita M Dreyer, Angèle Bénard, Gerd Pluschke (7855), Pluschke, Gerd, Bolz M, Oehlmann W, Singh M, Dreyer AM, Kerber S, Pluschke G, Duthie MS, Vettiger A, Bénard A   +35 more
core   +2 more sources

Exposure Risk for Infection and Lack of Human-to-Human Transmission of Mycobacterium ulcerans Disease, Australia

Emerging Infectious Diseases, 2017
We conducted epidemiologic and genetic analyses of family clusters of Mycobacterium ulcerans (Buruli ulcer) disease in southeastern Australia. We found that the incidence of M. ulcerans disease in family members was increased.
Daniel P. O’Brien, James W. Wynne, Andrew H. Buultjens, Wojtek P. Michalski, Timothy P. Stinear, N. Deborah Friedman, Andrew Hughes, Eugene Athan   +7 more
doaj   +1 more source

Genetic Diversity of PCR-Positive, Culture-Negative and Culture-Positive Mycobacterium ulcerans Isolated from Buruli Ulcer Patients in Ghana. [PDF]

, 2014
Culture of Mycobacterium ulcerans from Buruli ulcer patients has very low sensitivity. Thus confirmation of M. ulcerans infection is primarily based on PCR directed against IS2404.
Sarfo, S, Stephen Sarfo (521154), Small, P, Phillips, R, Heather Williamson (521153), Pamela Small, Pamela Small (521155), Richard Phillips, Heather Williamson, Wansbrough-Jones, M, Stephen Sarfo, Mark Wansbrough-Jones, Williamson, H, Richard Phillips (205457), Mark Wansbrough-Jones (347902)   +14 more
core   +1 more source

Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue. [PDF]

, 2010
BACKGROUND: Mycobacterium ulcerans disease (Buruli ulcer) is a neglected tropical disease common amongst children in rural West Africa. Animal experiments have shown that tissue destruction is caused by a toxin called mycolactone.
Engy A. Mahrous, Richard O. Phillips, Lee Richard E., Engy A Mahrous, Pamela L. Small, Lee, RE, Mark H. Wansbrough-Jones, Phillips Richard O., Sarfo, FS, Small, PL, Edward Tarelli, Pamela L Small, Mahrous, EA, Mark H Wansbrough-Jones, Wansbrough-Jones, MH, Kingsley B Asiedu, Tarelli, E, Rangers Brian, Rangers, B, Kingsley B. Asiedu, Mahrous Engy A., Tarelli Edward, Wansbrough-Jones Mark H., Richard O Phillips, Small Pamela L., Brian Rangers, Asiedu Kingsley B., Phillips, RO, Asiedu, KB, Sarfo Fred Stephen, Fred Stephen Sarfo, Richard E. Lee, Richard E Lee   +32 more
core   +1 more source

Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans. [PDF]

ACS Infect Dis
In the recent decade, scientific communities have toiled to tackle the emerging burden of drug-resistant tuberculosis (DR-TB) and rapidly growing opportunistic nontuberculous mycobacteria (NTM). Among these, two neglected mycobacteria species of the Acinetobacter family, Mycobacterium leprae and Mycobacterium ulcerans, are the etiological agents of ...
Shyam M, Kumar S, Singh V.
europepmc   +3 more sources

Development and application of new approaches to study the epidemiology of "mycobacterium ulcerans" disease (Buruli ulcer) in Ghana [PDF]

, 2012
Mycobacterium ulcerans, causing the devastating skin disease Buruli ulcer (BU), has evolved from the fish pathogen M. marinum. By the acquisition of a virulence plasmid (pMUM) a progenitor of M.
Röltgen, Katharina
core   +1 more source

Defining new Buruli ulcer endemic areas in urban southeastern Australia using bacterial genomics-informed possum excreta surveys

Applied and Environmental Microbiology
Buruli ulcer in southeastern Australia is a zoonosis caused by infection with Mycobacterium ulcerans. Australian native possums are a major wildlife reservoir, and infected possums shed M.
Andrew H. Buultjens, Koen Vandelannoote, Jessica L. Porter, Stephen Muhi, Emma C. Hobbs, Catarina Agostinho Antão, EE Laine Tay, Jake Lacey, Norelle Sherry, Maria Globan, Caroline J. Lavender, Anna Meredith, Paul D. R. Johnson, Katherine B. Gibney, Timothy P. Stinear   +14 more
doaj   +1 more source

Microbiological, histological, immunological, and toxin response to antibiotic treatment in the mouse model of Mycobacterium ulcerans disease. [PDF]

, 2013
Mycobacterium ulcerans infection causes a neglected tropical disease known as Buruli ulcer that is now found in poor rural areas of West Africa in numbers that sometimes exceed those reported for another significant mycobacterial disease, leprosy, caused
Jacques H Grosset, Deepak V Almeida, Robinson, C, Sarfo, FS, Jihui Zhang, Almeida, DV, Paul J Converse, Clive Robinson, Wansbrough-Jones, M, Mark Wansbrough-Jones, Grosset, JH, Fred Stephen Sarfo, Converse, PJ, Zhang, J   +13 more
core   +1 more source

Buruli ulcers in a Spanish aid worker after a stay in Peru

International Journal of Infectious Diseases, 2019
Buruli ulcer (BU) is a chronic and destructive infection of the skin and soft tissues caused by Mycobacterium ulcerans. Recently, population flows have triggered the appearance of several sporadic cases of BU in non-endemic countries.
Jose Manuel Guerra Laso, Teresa Nebreda Mayoral, Juan José Palacios Gutiérrez, Élia Samaniego González, Bárbara Rodríguez Martín, Leticia Barrio Rodríguez, Nieves Alonso Orcajo, Elena Magaz García, Timothy Stinear, Andrew H. Buultjens, Jose Antonio Pérez Molina   +10 more
doaj   +1 more source