Results 11 to 20 of about 130,955 (72)

ARVI in children: choice of approach in the treatment of cough

open access: yesМедицинский совет, 2020
According to official statistics,  acute  respiratory  infections  (ARI) always rank highest  among  the  infectious  diseases,  especially among  children.
L. S. Starostina
doaj   +1 more source

The Novel Role of Mitochondrial Citrate Synthase and Citrate in the Pathophysiology of Alzheimer’s Disease

open access: yesJournal of Alzheimer's Disease, 2023
Citrate synthase is a key mitochondrial enzyme that utilizes acetyl-CoA and oxaloacetate to form citrate in the mitochondrial membrane, which participates in energy production in the TCA cycle and linked to the electron transport chain.
Neeraj Chhimpa   +3 more
semanticscholar   +1 more source

Clinical efficiency of treatment of cough in pediatric practice

open access: yesМедицинский совет, 2019
Cough is one of the most common reasons why parents bring their children to the pediatrician. The article presents the results of a study of the clinical efficacy of treatment of dry cough using Sinecod syrup.
G. Yu. Evstifeeva   +3 more
doaj   +1 more source

Regional Citrate Anticoagulation versus No Anticoagulation for CKRT in Patients with Liver Failure with Increased Bleeding Risk

open access: yesAmerican Society of Nephrology. Clinical Journal, 2023
Visual Abstract Background The opinions on the efficacy and safety of no anticoagulation versus regional citrate anticoagulation for continuous KRT (CKRT) were controversial in patients with severe liver failure with a higher bleeding risk.
M. Bai   +14 more
semanticscholar   +1 more source

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia.

open access: yesCell Metabolism, 2022
Elevated liver de novo lipogenesis contributes to non-alcoholic steatohepatitis (NASH) and can be inhibited by targeting acetyl-CoA carboxylase (ACC). However, hypertriglyceridemia limits the use of pharmacological ACC inhibitors as a monotherapy.
Marisa R. Morrow   +21 more
semanticscholar   +1 more source

Cough. What shall we do, how can we help?

open access: yesМедицинский совет, 2015
The article tells about the main causes of cough in children, differential diagnosis of cough in various bronchopulmonary diseases. The key features of major diseases associated with cough symptoms are described; current approaches to the choice of ...
E. M. Ovsyannikova   +4 more
doaj   +1 more source

Selective autophagic degradation of ACLY (ATP citrate lyase) maintains citrate homeostasis and promotes oocyte maturation

open access: yesAutophagy, 2022
Macroautophagy/autophagy is a cellular and energy homeostatic mechanism that contributes to maintain the number of primordial follicles, germ cell survival, and anti-ovarian aging.
Hainan He   +20 more
semanticscholar   +1 more source

Engineering multifunctional bioactive citrate-based biomaterials for tissue engineering

open access: yesBioactive Materials, 2022
Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine. Citrate-based polymers are the few bioactive polymer biomaterials used in biomedicine because of their facile ...
Min Wang, Peng Xu, B. Lei
semanticscholar   +1 more source

Methemoglobinemia - Two Uncommon Presentations

open access: yes, 2020
Two rather different cases of methemoglobinemia are presented. The first case is an infant who had a circumcision procedure with prilocaine. The second case involves a 14-year-old girl who attempted suicide with an overdose of metoclopramide and ...
Zuhal Gundogdu   +2 more
semanticscholar   +1 more source

Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update

open access: yesInternational Journal of Molecular Sciences, 2021
Citrate plays a central role in cancer cells’ metabolism and regulation. Derived from mitochondrial synthesis and/or carboxylation of α-ketoglutarate, it is cleaved by ATP-citrate lyase into acetyl-CoA and oxaloacetate.
P. Icard   +7 more
semanticscholar   +1 more source

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