A Catalytic One-Pot Synthesis of Indolyl Cyclobutanones [PDF]
, 2021 A general strategy for the synthesis of indolyl cyclobutanones via a tandem Bronsted acid catalyzed 2-hydroxycyclobutanone activation-indole nucleophilic addition has been exploited.
Frongia A. +3 more
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Reactions of cyclobutenones with nucleophilic reagents via vinylketen intermediates [PDF]
, 1976 While strong nucleophiles add to the endocyclic double bond of cyclobutenones to yield cyclobutanones, weaker nucleophiles (e.g. alcohols, aniline) interact with the vinylketens which are thermally or photochemically generated from cyclobutenones; the ...
Huisgen, Rolf, Mayr, Herbert
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Synthesis of functionalized tryptamines by Brønsted acid catalysed cascade reactions [PDF]
, 2015 An original synthetic protocol has been developed for the preparation of highly functionalized tryptamines from 2-hydroxycyclobutanone and secondary arylamines via a solvent-free Brønsted acid catalysed two-step reaction ...
Aitken, David J +4 more
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Modular access to substituted azocanes via a rhodium-catalyzed cycloaddition-fragmentation strategy [PDF]
, 2015 A short entry to substituted azocanes by a Rh-catalyzed cycloaddition–fragmentation process is described. Specifically, exposure of diverse N-cyclopropylacrylamides to phosphine-ligated cationic Rh(I) catalyst systems under a CO atmosphere enables the ...
Bower, John F. +3 more
core +7 more sources
Synthesis of Silylated Cyclobutanone and Cyclobutene Derivatives Involving 1,4‐Addition of Zinc‐Based Silicon Nucleophiles [PDF]
, 2021 A copper‐catalyzed conjugate silylation of various cyclobutenone derivatives with Me2PhSiZnCl ⋅ 2LiCl or (Me2PhSi)2Zn ⋅ xLiCl (x≤4) to generate β‐silylated cyclobutanones is reported.
Cui, Ming, Oestreich, Martin
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A novel and efficient method to prepare 2-aryltetrahydrofuran-2-ylphosphonic acids
Beilstein Journal of Organic Chemistry, 2010 A novel one-pot method was developed for the synthesis of the title compounds starting from 4-chloro-1-aryl-1-butanones 1, phosphorus trichloride and acetic acid. The end products 2 were obtained in 20–94% yield.
Vsevolod V. Komissarov +2 more
doaj +1 more source
Synthesis and Applications of Rhodacyclopentanones Derived From C-C Bond Activation [PDF]
, 2016 Rhodacyclopentanones, an “sp(3)-rich” class of metallacycle, underpin an emerging range of catalytic methodologies for the direct generation of complex scaffolds.
Bower, John, Shaw, Megan H
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Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-γ-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site [PDF]
, 2021 An α-amido cyclobutanone possessing a C10 hydrocarbon tail was designed as a potential transition-state mimetic for the quorum-quenching metallo-γ-lactonase autoinducer inactivator A (AiiA) with the support of in-house modeling techniques and found to be
Becker, Daniel P, Ph.D. +7 more
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Novel foods and food ingredients: what is the mission of scientists and technologists? [PDF]
, 2000 The situation concerning world food production is changing dramatically. On the one hand, the world population is expected to grow still further, reaching about 8 billion peo- ple in the middle of the 21st century.
Bibiloni +26 more
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Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles [PDF]
, 2017 A two-step stereoselective chemoenzymatic synthesis of optically active α-aryl-substituted oxygen heterocycles was developed, exploiting a whole-cell mediated asymmetric reduction of α-, β-, and γ-chloroalkyl arylketones followed by a stereospecific ...
AGRIMI, GENNARO +7 more
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