Results 121 to 130 of about 174,283 (288)

Mixed Evidence for Impact of Early Infant Gut Microbiome and Later Development of Autism Spectrum Disorder in the MARBLES Prospective Cohort Study

Autism Research, EarlyView.
ABSTRACT This study investigated the relationship between early infant gut microbiome composition and subsequent neurodevelopmental outcomes. Fecal samples from children in the markers of autism risks in babies‐learning early signs (MARBLES) study, a cohort with elevated likelihood of autism, were collected between 0 and 7 months of age and analyzed ...
Jennie Sotelo‐Orozco, Diana H. Taft, Jassim Al‐Oboudi, Brittany C. Baikie, Cailyn Lake, Meghan Miller, David A. Mills, Daniel J. Tancredi, Rebecca J. Schmidt, Irva Hertz‐Picciotto, Deborah H. Bennett   +10 more
wiley   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Unravelling the initiator‐only stage in alginate grafting: Radical‐induced depolymerization and its impact on acrylamide grafting efficiency

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Free‐radical grafting of natural polymers often assumes that initiators only create active sites before monomer addition. We tested this by exposing sodium alginate to potassium persulphate (KPS) under typical grafting conditions without monomer (acrylamide).
Gustavo P. Zago, João B. P. Soares
wiley   +1 more source

Polyhydroxybutyrate accumulation by a Serratia sp [PDF]

, 2008
A strain of Serratia sp. showed intracellular electron-transparent inclusion bodies when incubated in the presence of citrate and glycerol 2-phosphate without nitrogen source following pregrowth under carbon-limitation in continuous culture.
Hewitt, CJ, Jenkins, M, Kashani, M, Lugg, H, Macaskie, LE, Marquis, PM, Paterson-Beedle, M, Redwood, MD, Sammons, RL, Stamboulis, A, Yong, P   +10 more
core  

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Gut microbial metabolite butyrate suppresses hepatocellular carcinoma growth via CXCL11-dependent enhancement of natural killer cell infiltration

Gut Microbes
Gut microbiota-derived butyrate plays a vital role in attenuating hepatocellular carcinoma (HCC) in murine models. However, the precise molecular mechanisms by which butyrate exerts its effects are largely undefined. Plasma short-chain fatty acids (SCFAs)
Menghan Zhang, Xuefeng Huang, Yanlong Zhang, Minghang Yu, Xiaoxue Yuan, Yifan Xu, Lei Ma, Xi Wang, Huichun Xing   +8 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Butyrate and mucosal inflammation: New scientific evidence supports clinical observation [PDF]

, 2015
Alvarado, David M., Ciorba, Matthew A., Cushing, Kelly   +2 more
core   +3 more sources