Results 131 to 140 of about 104,308 (265)

Butyrate combined with niacin enhances intestinal barrier function repair in weaned piglets infected with ETEC by promoting colonic metabolism and antimicrobial peptide expression. [PDF]

J Anim Sci Biotechnol
Tang Q, Zhen R, Yang B, Miao Z, Wei Y, Ruan S, He Y, Xiong Y, Wu Q, Wang L, Jiang Z, Yi H.   +11 more
europepmc   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Primary cilia in the hypothalamic AgRP neurons mediate metabolic effects of butyrate. [PDF]

Nat Commun
Rijal S, Yang DJ, Doan KV, Lyoo SH, Lee A, Choi YH, Shin DM, Kim KW.   +7 more
europepmc   +1 more source

The role of human microbiota in breast cancer pathogenesis and treatment

iMeta, EarlyView.
The human microbiota contributes to breast cancer pathogenesis and treatment response through interactions involving the oral, gut, and breast microbial niches. (Left) Multi‐site dysbiosis is characterized by altered microbial composition and abundance across different anatomical sites.
Jie Qiu, Xiaojia Wang, Man Li, Jing Guo, Shipeng Ning, Yi‐Zhou Gao, Xinyi Zhang, Xuli Meng, Yiding Chen, Yunxiang Zhou   +9 more
wiley   +1 more source

Butyrate protects against Klebsiella pneumoniae-induced oxidative stress in alveolar macrophages via p62-Keap1-Nrf2 pathway. [PDF]

Redox Biol
Meng B, Li H, Tang M, Zhu J, Yao R, Xu Y, Zhang Q, Zhu R, Guo Y, Xu Y, Shu Y, Yu L, Li Y, Yang Y, Liu Y, Wu T, Li J.   +16 more
europepmc   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Sodium butyrate protects against necrotizing enterocolitis through a mechanism involving YB-1-dependent regulation of intestinal epithelial apoptosis. [PDF]

Sci Rep
Xiang Q, Yu R, Huang L, Liu Q, Qin N, Wang L, Wu Y, Fu H.   +7 more
europepmc   +1 more source

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Effect of microencapsulated sodium butyrate on abdominal symptoms and carbohydrate metabolism in patients with type 2 diabetes: a randomized placebo-controlled trial. [PDF]

Sci Rep
Panufnik P, Więcek M, Szwarc P, Szydlarska D, Kadaj-Lipka R, Franek E, Rydzewska G.   +6 more
europepmc   +1 more source

Microbial DNA methylation links rumen transcriptional activity to methane emission divergence in dairy cows

iMeta, EarlyView.
Genome‐resolved methylomics uncovers the first DNA methylation atlas of the dairy cow rumen microbiome. Microbial DNA methylation profiles diverge between low‐ and high‐ methane‐emitting dairy cows despite limited taxonomic differences. Differential methylation is linked to transcriptional variation in genes involved in carbon metabolism, hydrogen ...
Xinyue Zhang, Guirong Xu, Liwei Zhao, Ye Tao, Jiawei Zhang, Cameron E. F. Clark, Yangyi Hao, Zhijun Cao, Shengli Li, Wei Wang   +9 more
wiley   +1 more source