Results 131 to 140 of about 133,313 (256)

Buried Interface Engineering via a Bifunctional Guanidino‐Carboxyl Molecular Bridge for Enhanced Performance and Stability in Perovskite Solar Cells

EcoEnergy, EarlyView.
A bifunctional molecular bridge using 4‐guanidinobutanoic acid (GCC) is constructed to comprehensively tailor the buried interface of PSCs. By passivating oxygen vacancies, optimizing energy‐level matching, and regulating perovskite crystallization, this strategy simultaneously boosts the power conversion efficiency to 25.37% (20.01% for 13.4 cm2) and ...
Ying Liang, Wenjing Zhou, Yongxuan Zhou, Jiahao Cheng, Wenjian Shen, Guijie Liang, Bin Li, Yong Peng, Zaifang Li, Liu Liu, Jun Yao, Yi‐Bing Cheng, Wangnan Li   +12 more
wiley   +1 more source

A butyrate‐producing synbiotic mitigates intestinal inflammation in a murine colitis model

mLife
Inflammatory bowel disease (IBD) is a chronic condition characterized by intestinal inflammation and gut dysbiosis, with limited treatment options primarily focused on immune‐modulating therapies.
Hyuna Sung, Soo Yoon Cho, Seong Hyeok Ma, Jin Sun You, Mi Young Yoon, Sang Sun Yoon   +5 more
doaj   +1 more source

Microbiota-derived short-chain fatty acids in hematopoietic stem cell transplantation: immunomodulation at the host-microbiota interface

Frontiers in Microbiology
Hematopoietic stem cell transplantation (HSCT) remains a cornerstone treatment for many hematological malignancies, but its clinical success is still challenged by graft-vs.-host disease (GvHD), infectious complications, and the profound microbial ...
Crystel Hajjar, Ed J. Kuijper, Ed J. Kuijper, Marie-José Butel, Gaelle Khoury, May Mallah, Dolla Karam Sarkis, Philippe Lesnik, Wilfried Le Goff, Ali Bazarbachi, Marianne Abifadel, Marianne Abifadel, Marianne Abifadel   +12 more
doaj   +1 more source

Carbon Anodes for Low‐Temperature Nonaqueous Alkali Metal‐Ion Batteries

EcoEnergy, EarlyView.
This review summarizes recent progress in carbon anodes for low‐temperature nonaqueous alkali‐metal ion batteries. Fundamental thermodynamic and kinetic limitations are examined, alongside a systematic discussion of graphite, hard carbon, and emerging carbon architectures.
Zhichun Miao, Dandan Yu, Guojie Liu, Yuyang Qin, Jingyun Mou, Wenlong Song, Lu Shi, Zengqin Xiao, Xin Yuan, Huayu Chen, Laishun Qin, Da Chen   +11 more
wiley   +1 more source

Charting Water‐in‐Natural‐Salt (WiNS) Electrolytes. Part I: Effect of Anion's Alkyl Tail Length

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
At 20 m, potassium carboxylates from formate to butyrate reveal anion tail‐controlled nanostructure. SAXS shows a pre‐peak shifting to lower q with chain length. Molecular dynamics reproduces S(q) and attributes it to concentration fluctuations forming bicontinuous segregation.
Alessandra Del Giudice, Laura Hildebrandt, Jin Han, Radhika Krishna Hema, Luciano Galantini, Stefano Passerini, Alberto Varzi, Alessandro Mariani   +7 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Butyrate-Dependent Conformational Switch Promotes Nuclear Translocation of the Mustard Allergen Sin a 1 in Human Gut Epithelial Cells.

Funding: This work was supported by grant PID2020-116692RBI00 from the Spanish Ministry of Science, Innovation and Universities (MICIU/AEI/10.13039/501100011033), and cofounded by the European Regional Development Fund.Rubeń G.
Turnay Abad, Francisco Javier, Batanero Cremades, Eva, García Gordo, Rubén, Villalba Díaz, María Teresa, Olmo López, Nieves, Parrón Ballesteros, Jorge   +5 more
core   +1 more source

Enhancing Lentiviral Purification: Combining CIM QA Monolithic Columns With Design of Experiments Approach

ELECTROPHORESIS, EarlyView.
Lentiviral vector purification using QA CIM monolith anion‐exchange chromatography was optimized via 96‐well and DOE, increasing recovery from 20% to 90%. The process achieved 3.3‐log host cell protein reduction, decreased particle impurities, and showed high binding capacity, supporting large‐scale manufacturing.
Luka Bevc, Ana Pavšič Rijavec, Valentina Novak, Sandra Potušek Šuleski, Ivana Petrović Koshmak, Maja Leskovec, Hana Jug, Aleš Štrancar   +7 more
wiley   +1 more source

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

Epilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi, John Williamson, Jhanvi Patel, Samikksha Kumar, Huayu Sun, Lucy Dang Nguyen, Katarzyna Rękawek, Ifrah Zawar, Jaideep Kapur   +8 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source