Butyrate Ameliorates ISO-Induced Cardiac and Intestinal Injury in Rats via Modulation of Bitter Taste Receptors (Tas2rs) and GPR41/43 to Inhibit NLRP3 Activation. [PDF]
Yu T, Cao A, Zhu F, Xie Z, Hu S, Li D.
europepmc +1 more source
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
The Influence of Bovine Colostrum and Sodium Butyrate Supplementation on Gut Microbiota and the Intestinal-Liver Axis in Weaned Piglets. [PDF]
Pieszka M +10 more
europepmc +1 more source
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying +6 more
wiley +1 more source
Gut microbial metabolites in colorectal cancer: dual roles in tumorigenesis, immune crosstalk, and therapeutic innovation. [PDF]
Jin Y, Zhu H, Fan J, Xu H.
europepmc +1 more source
Butyrate Is Associated with the Antidepressant Effects of <i>Weizmannia coagulans</i> BC99: Functional Similarity of a Microbial Metabolite in the Microbiota-Gut-Brain Axis. [PDF]
Zhou Y +6 more
europepmc +1 more source
The microbiota-metabolite-immune axis in colorectal cancer: mechanistic insights and emerging clinical applications. [PDF]
Sun B, Wang T.
europepmc +1 more source
Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia +11 more
wiley +1 more source
Preventive Effect of Butyrate in Colon Cancer Cell Metabolism. [PDF]
Gonçalves TJ +8 more
europepmc +1 more source
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou +29 more
wiley +1 more source

