Results 1 to 10 of about 405,626 (304)

Short-chain fatty acids in diseases

open access: yesCell Communication and Signaling, 2023
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such as monocarboxylate transporter 1 and sodium ...
Dan Zhang   +9 more
doaj   +3 more sources

Occurrence and distribution of ladderane oxidation products in different oceanic regimes [PDF]

open access: yesBiogeosciences, 2012
Ladderane fatty acids are commonly used as biomarkers for bacteria involved in anaerobic ammonium oxidation (anammox). These lipids have been experimentally shown to undergo aerobic microbial degradation to form short chain ladderane fatty acids. However,
D. Rush   +4 more
doaj   +5 more sources

The Divergent Immunomodulatory Effects of Short Chain Fatty Acids and Medium Chain Fatty Acids

open access: yesInternational Journal of Molecular Sciences, 2021
Fatty acids are derived from diet and fermentative processes by the intestinal flora. Two to five carbon chain fatty acids, termed short chain fatty acids (SCFA) are increasingly recognized to play a role in intestinal homeostasis. However, the characteristics of slightly longer 6 to 10 carbon, medium chain fatty acids (MCFA), derived primarily from ...
Qi Hui Sam, Hua Ling, Wen Shan Yew
exaly   +3 more sources

The pharmacology and function of receptors for short-chain fatty acids [PDF]

open access: yesMolecular Pharmacology, 2015
Despite some blockbuster G protein–coupled receptor (GPCR) drugs, only a small fraction (∼15%) of the more than 390 nonodorant GPCRs have been successfully targeted by the pharmaceutical industry.
Bolognini, Daniele   +3 more
core   +5 more sources

Short-chain fatty acids activate acetyltransferase p300 [PDF]

open access: yeseLife, 2021
Short-chain fatty acids (SCFAs) acetate, propionate, and butyrate are produced in large quantities by the gut microbiome and contribute to a wide array of physiological processes. While the underlying mechanisms are largely unknown, many effects of SCFAs
Sydney P Thomas, John M Denu
doaj   +3 more sources

Regulation of Inflammation by Short Chain Fatty Acids [PDF]

open access: yesNutrients, 2011
The short chain fatty acids (SCFAs) acetate (C2), propionate (C3) and butyrate (C4) are the main metabolic products of anaerobic bacteria fermentation in the intestine. In addition to their important role as fuel for intestinal epithelial cells, SCFAs modulate different processes in the gastrointestinal (GI) tract such as electrolyte and water ...
Marco Aurélio Ramirez Vinolo   +2 more
exaly   +3 more sources

Short-chain fatty acids in nonalcoholic fatty liver disease: New prospects for short-chain fatty acids as therapeutic targets

open access: yesHeliyon
Nonalcoholic fatty liver disease (NAFLD) is a stress-induced liver injury related to heredity, environmental exposure and the gut microbiome metabolism.
Xinyu Li   +7 more
doaj   +3 more sources

Short-chain fatty acids are potential goalkeepers of atherosclerosis

open access: yesFrontiers in Pharmacology, 2023
Short-chain fatty acids (SCFAs) are metabolites produced by gut bacteria and play a crucial role in various inflammatory diseases. Increasing evidence suggests that SCFAs can improve the occurrence and progression of atherosclerosis.
Yu Feng, Danyan Xu
doaj   +3 more sources

Role of short‐chain fatty acids in host physiology

open access: yesAnimal Models and Experimental Medicine
Short‐chain fatty acids (SCFAs) are major metabolites produced by the gut microbiota through the fermentation of dietary fiber, and they have garnered significant attention due to their close association with host health.
Mingyue Liu   +9 more
doaj   +3 more sources

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