Results 151 to 160 of about 121,706 (306)

Food‐grade proteins, lipids, and fibers as potential tools to ameliorate cardiovascular disorders: A review

Food Biomacromolecules, EarlyView.
Abstract Cardiovascular diseases (CVDs) remain the leading cause of global mortality, necessitating effective preventive and adjunct therapeutic strategies beyond conventional pharmacological interventions. Although previous reviews have focused on individual nutrients or dietary patterns, this review provides a mechanism‐based, integrative perspective
Sridevi Shanmugam, Rukaiah Fatma Begum, Nirenjen Shanmugasundaram, Bhupendra Gopalbhai Prajapati, Suresh Ankul Singh, Pavithra Nagenthran, Sudarshan Singh, Kesarla Rajesh   +7 more
wiley   +1 more source

Pathway of butyrate catabolism by Desulfobacterium cetonicum

, 1995
Desulfobacterium cetonicum 480 oxidized butyrate to 1 mol of acetate and 2 mol of CO2; this reaction was coupled to reduction of sulfate to sulfide. Butyrate was activated by coenzyme A (CoA) transfer from acetyl- CoA, and butyryl-CoA was oxidized to ...
Schink, Bernhard, Janssen, Peter H.
core  

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Differential analysis of Short chain fatty acids incubation in autistic organoids based on transcriptome sequencing. [PDF]

PLoS One
Wu Z, Liu X, Han X, Li M.
europepmc   +1 more source

Bifidobacterium animalis BGI‐L99 Ameliorates Polycystic Ovary Syndrome by Modulating the Gut Microbiota‐Bile Acid‐IL‐22 Axis

iMetaMed, EarlyView.
Polycystic ovary syndrome (PCOS) is described as a complex endocrine‐metabolic disorder frequently accompanied by reproductive dysfunction and depression‐like behaviors. During PCOS progression, gut microbiota dysbiosis and systemic bile acid disturbances co‐occur, severely disrupting host immune and metabolic homeostasis. B.
Haoyu Wang, Weixuan Chen, Xiaofang Li, Xiaohong Lu, Tianli Liu, Jiarui Liang, Yajie Wang, Mengzhen Jia, Ruiyu Zhang, Yuzheng Gu, Jielei Zhu, Jiayi Ma, Zhinan Wu, Yiyi Zhong, Haifeng Zhang, Tao Yang, Liang Xiao, Zhigang Liu, Yuanqiang Zou   +18 more
wiley   +1 more source

Infusion of butyrate affects plasma glucose, butyrate, and β-hydroxybutyrate but not plasma insulin in lactating dairy cows

, 2018
The objective of this study was to investigate the effects on plasma metabolites and rumen traits when butyrate was infused into the rumen or abomasum of lactating cows. Jugular catheters were inserted into 5 ruminally fistulated Holstein cows [94.2 ± 26.
Kalschuer, K. F., Anderson, J. L., van Eys, J. E., Herrick, K. J., Ranathunga, D. J., Moreland, S. C., Hippen, A. R.   +6 more
core  

The role of human microbiota in breast cancer pathogenesis and treatment

iMeta, EarlyView.
The human microbiota contributes to breast cancer pathogenesis and treatment response through interactions involving the oral, gut, and breast microbial niches. (Left) Multi‐site dysbiosis is characterized by altered microbial composition and abundance across different anatomical sites.
Jie Qiu, Xiaojia Wang, Man Li, Jing Guo, Shipeng Ning, Yi‐Zhou Gao, Xinyi Zhang, Xuli Meng, Yiding Chen, Yunxiang Zhou   +9 more
wiley   +1 more source

Butyrate Ameliorates ISO-Induced Cardiac and Intestinal Injury in Rats via Modulation of Bitter Taste Receptors (Tas2rs) and GPR41/43 to Inhibit NLRP3 Activation. [PDF]

Nutrients
Yu T, Cao A, Zhu F, Xie Z, Hu S, Li D.
europepmc   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source