Results 161 to 170 of about 3,215 (244)

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Butyrate-producing Eubacterium rectale inhibits gastric carcinogenesis and augments the efficacy of immunotherapy. [PDF]

J Transl Med
Gao W, Xiong J, Wu G, Chen Y, Lin X.
europepmc   +1 more source

Effects of Live and Heat‐Treated Bifidobacterium longum CECT 7347 in Adults With Allergic Rhinitis: A Randomised, Double‐Blind, Placebo‐Controlled Trial

Allergy, EarlyView.
This randomized, double‐blind, placebo‐controlled trial evaluated the effects of live probiotic and HT postbiotic B. longum CECT 7347 in adults with moderate–severe allergic rhinitis. Postbiotic supplementation for 8 weeks significantly reduced CSMS and dSS, exceeding the established CSMS MCID with a 33% greater improvement, when compared to placebo ...
Ana Cardoso, Malwina Naghibi, Eric Climent, Andrea Rodenes‐Gavidia, Araceli Lamelas, Laura Llobregat, Juan Martínez‐Blanch, Daniel Friedman, Vineetha Vijayakumar, Richard Day   +9 more
wiley   +1 more source

The Gut Microbiome and Butyrate Differentiate Clostridioides difficile Colonization and Infection in Children. [PDF]

J Infect Dis
Nicholson MR, Ma S, Strickland BA, Cecala M, Zhang L, Reasoner S, Guiberson ER, Munneke MJ, Shilts MH, Skaar EP, Das SR.   +10 more
europepmc   +1 more source

Longitudinal Follow‐Up of Gut and Salivary Microbiota in Children With Food Protein‐Induced Enterocolitis Syndrome

Allergy, EarlyView.
This study aimed to compare both the gut and salivary microbiota over time between allergic and tolerant patients and matched controls. Allergic patients with food protein‐induced enterocolitis syndrome exhibited lower gut and salivary alpha‐diversities, several genus‐level differences, and higher acetate levels than controls.
Anais Lemoine, Karine Adel‐Patient, Nathalie Kapel, Camille Mayeur, Marie‐Noelle Rossignol, Aurelia Bruneau, Patrick Tounian, Muriel Thomas, Ioannis Nicolis   +8 more
wiley   +1 more source

Ultra‐Processed Food Consumption and Childhood Allergic Diseases: Increased Risk of Asthma Onset in the SENDO Project

Allergy, EarlyView.
The SENDO cohort study (2015–2024) prospectively analyzed the impact of ultra‐processed food (UPF) consumption on asthma and atopy in 1,546 Spanish children. Higher UPF intake (NOVA 4 classification) was significantly associated with an increased risk of asthma but not atopy, atopic dermatitis, neumoallergen sensitation, food allergy over five years ...
O. Galindo, M. J. Goikoetxea, L. Moreno‐Galarraga, L. Argiz, J. M. Moreno‐Villares, Victor de la O, N. Martín‐Calvo   +6 more
wiley   +1 more source

Fecal butyrate and deoxycholic acid quantitation for rapid assessment of the gut microbiome. [PDF]

PLoS One
Mullowney MW, Moran A, Hernandez A, McMillin M, Rose AR, Moran D, Little J, Nguyen AB, Patel BK, Lehmann CJ, Odenwald MA, Pamer EG, Yeo KJ, Sidebottom AM.   +13 more
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Butyrate blocks cell cycle progression in colorectal cancer organoids partially through HDAC2 inhibition. [PDF]

Front Immunol
Liu B, Huang Y, Wang X, Liu X, Luo Y, Wang N, Tian H, Huang L, Xu Z, Lang J, Lei X, Liu D.   +11 more
europepmc   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source