Results 1 to 10 of about 110,014 (118)

Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease

Cells, 2021
The microbial metabolite butyrate serves as a link between the intestinal microbiome and epithelium. The monocarboxylate transporters MCT1 and SMCT1 are the predominant means of butyrate transport from the intestinal lumen to epithelial cytoplasm, where ...
Robert A Cowles, Pooja S Salvi
exaly   +3 more sources

Butyrate producers, “The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics

Frontiers in Microbiology, 2023
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological importance than the other major SCFAs (acetate and propionate).
Jae-Ho Shin, Tatsuya Unno
exaly   +3 more sources

Butyrate Properties in Immune-Related Diseases: Friend or Foe?

Fermentation, 2023
Butyrate is a short-chain fatty acid (SCFA) created within the intestinal lumen by bacterial fermentation of largely undigested dietary carbohydrates.
Muhammad Anshory, Raden Mohamad Rendy Ariezal Effendi, Handono Kalim, Reiva Farah Dwiyana, Oki Suwarsa, Tamar E. C. Nijsten, Jan L. Nouwen, Hok Bing Thio   +7 more
doaj   +1 more source

Encapsulation of butyrate using low-alkali konjac gel induced by ethanol for colonic delivery

Food Hydrocolloids for Health, 2021
Butyrate administrated in proper concentration is beneficial to the human colon environment. However, the delivery of butyrate to the colon is quite difficult as butyrate could be easily absorbed in the upper gastrointestinal tract.
Yousong Ma, Sijia Peng, Ning Tang, Yongqiang Cheng   +3 more
doaj   +1 more source

Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice

Gut Microbes, 2021
Emerging research evidence has established the critical role of the gut-liver axis in the development of alcohol-associated liver disease (ALD). The present study employed 16S rRNA gene and whole genome shotgun (WGS) metagenomic analysis in combination ...
Richa Singhal, Hridgandh Donde, Smita Ghare, Kendall Stocke, Jingwein Zhang, Manicka Vadhanam, Sreelatha Reddy, Leila Gobejishvili, Paula Chilton, Swati Joshi-Barve, Wenke Feng, Craig McClain, Kristi Hoffman, Joseph Petrosino, Marius Vital, Shirish Barve   +15 more
doaj   +1 more source

Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression

Redox Biology, 2023
Ferroptosis has emerged to be a promising approach in cancer therapies; however, colorectal cancer (CRC) is relatively insensitive to ferroptosis. Exactly how the gut microenvironment impacts the ferroptotic sensitivity of CRC remains unknown. Herein, by
Ying He, Yuhang Ling, Zhiyong Zhang, Randall Tyler Mertens, Qian Cao, Xutao Xu, Ke Guo, Qian Shi, Xilin Zhang, Lixia Huo, Kan Wang, Huihui Guo, Weiyun Shen, Manlu Shen, Wenming Feng, Peng Xiao   +15 more
doaj   +1 more source

In vitro Fermentation Reveals Changes in Butyrate Production Dependent on Resistant Starch Source and Microbiome Composition

Frontiers in Microbiology, 2021
One of the primary benefits associated with dietary resistant starch (RS) is the production of butyrate by the gut microbiome during fermentation of this fiber in the large intestine. The ability to degrade RS is a relatively rare trait among microbes in
June Teichmann, Darrell W. Cockburn
doaj   +1 more source

Alternative splicing regulated by butyrate in bovine epithelial cells. [PDF]

PLoS ONE, 2012
As a signaling molecule and an inhibitor of histone deacetylases (HDACs), butyrate exerts its impact on a broad range of biological processes, such as apoptosis and cell proliferation, in addition to its critical role in energy metabolism in ruminants ...
Sitao Wu, Congjun Li, Wen Huang, Weizhong Li, Robert W Li   +4 more
doaj   +1 more source

Effect of in feed administration of different butyrate formulations on Salmonella Enteritidis colonization and cecal microbiota in broilers

Veterinary Research, 2020
Butyrate has been used extensively as a feed additive to improve gut health and to decrease Salmonella colonization in poultry. Salmonella mainly colonizes the ceca so butyrate concentrations should be increased in this gut segment.
Lonneke Onrust, Steve Baeyen, Freddy Haesebrouck, Richard Ducatelle, Filip Van Immerseel   +4 more
doaj   +1 more source

Higher total faecal short-chain fatty acid concentrations correlate with increasing proportions of butyrate and decreasing proportions of branched-chain fatty acids across multiple human studies

Gut Microbiome, 2022
Metabolites produced by microbial fermentation in the human intestine, especially short-chain fatty acids (SCFAs), are known to play important roles in colonic and systemic health.
Maria LaBouyer, Grietje Holtrop, Graham Horgan, Silvia W. Gratz, Alvaro Belenguer, Nicola Smith, Alan W. Walker, Sylvia H. Duncan, Alexandra M. Johnstone, Petra Louis, Harry J. Flint, Karen P. Scott   +11 more
doaj   +1 more source