Results 11 to 20 of about 225,175 (395)
The microbial metabolite butyrate serves as a link between the intestinal microbiome and epithelium. The monocarboxylate transporters MCT1 and SMCT1 are the predominant means of butyrate transport from the intestinal lumen to epithelial cytoplasm, where ...
Pilyung Stephen Oh, Robert A Cowles
exaly +4 more sources
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological importance than the other major SCFAs (acetate and propionate).
Vineet Singh, Tatsuya Unno, Hong Koh
exaly +4 more sources
Ferroptosis has emerged to be a promising approach in cancer therapies; however, colorectal cancer (CRC) is relatively insensitive to ferroptosis. Exactly how the gut microenvironment impacts the ferroptotic sensitivity of CRC remains unknown. Herein, by
Ying He +15 more
doaj +2 more sources
Isolation and characterization of Faecalibacterium prausnitzii from calves and piglets. [PDF]
The goal of our study was to isolate and characterize Faecalibacterium prausnitzii from fecal samples of healthy calves and piglets, in order to develop a novel probiotic for livestock animals.
Bicalho, Rodrigo C +6 more
core +13 more sources
Butyrate Properties in Immune-Related Diseases: Friend or Foe?
Butyrate is a short-chain fatty acid (SCFA) created within the intestinal lumen by bacterial fermentation of largely undigested dietary carbohydrates.
Muhammad Anshory +7 more
doaj +1 more source
Objective Roseburia intestinalis is a probiotic species that can suppress intestinal inflammation by producing metabolites. We aimed to study the role of R. intestinalis in colorectal tumourigenesis and immunotherapy. Design R. intestinalis abundance was
X. Kang +9 more
semanticscholar +1 more source
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also signals through three G-protein coupled receptors. It is clear that butyrate
K. Hodgkinson +7 more
semanticscholar +1 more source
Encapsulation of butyrate using low-alkali konjac gel induced by ethanol for colonic delivery
Butyrate administrated in proper concentration is beneficial to the human colon environment. However, the delivery of butyrate to the colon is quite difficult as butyrate could be easily absorbed in the upper gastrointestinal tract.
Yousong Ma +3 more
doaj +1 more source
Polyvinyl Butyrate Nanoparticles as Butyrate Donors for Colitis Treatment
Butyrate has been attracting attention for the suppression of inflammatory bowel disease (IBD). However, clinical trials of butyrate for IBD treatment have resulted in controversial outcomes, likely owing to the adverse effect of butyrate on the intestinal epithelium that was observed at high butyrate concentrations.
Yunmei Mu +9 more
openaire +3 more sources
Background and objective: Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is a chronic inflammatory disorder characterized by aberrant immune responses and compromised barrier function in the gastrointestinal tract ...
Neeraja Recharla +2 more
semanticscholar +1 more source

