Results 31 to 40 of about 133,313 (256)
Evidence for proton-pump inhibitor (PPI)-associated dysbiosis in metabolically unhealthy obesity
Frontiers in Endocrinology, 2023 Obesity adversely impacts millions of American adults by predisposing them to significant health risks and further complications. Obesity is differentiated into two groups: metabolically healthy and metabolically unhealthy.
Melissa A. Burmeister +3 more
doaj +1 more source
Butyrate protects endothelial function through PPARδ/miR-181b signaling
, 2021 Reports of the beneficial roles of butyrate in cardiovascular diseases, such as atherosclerosis and ischemic stroke, are becoming increasingly abundant. However, the mechanisms of its bioactivities remain largely unknown.
Francis M. Chen +7 more
core
Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity [PDF]
, 2011 Background Diets high in cereal-fiber (HCF) have been shown to improve whole-body insulin sensitivity. In search for potential mechanisms we hypothesized that a supplemented HCF-diet influences the composition of the human gut microbiota and/or ...
Pfeiffer, Andreas F. H. +26 more
core +1 more source
, 2016 Butyrate, a fermentation product of the large bowel microflora, is potentially protective against the development of colorectal cancer. In vitro, butyrate has been shown to induce apoptosis and inhibit proliferation in numerous cancer cell lines ...
Richard Head (2217217) +8 more
core +3 more sources
Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia
BMC PediatricsBackground Previous studies have found a reduction in butyrate-producing bacteria in the gut microbiota of infants with biliary atresia (BA). Butyrate is also an important inhibitor of histone deacetylase 2 (HDAC2).
Yilin Zhao +10 more
doaj +1 more source
Microbiota changes after butyrate.
, 2022 P values for the changes in fecal microbiota between the baseline and the end of the 3-week follow-up (time3). Data are shown for the group with the standard salt substitution (treatment_standard; 0 weeks vs 3 weeks), and for the group attending the ...
Aki Saarikivi (12850879) +15 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Biomolecules, 2021 Butyrate is formed in the gut during bacterial fermentation of dietary fiber and is attributed numerous beneficial effects on the host metabolism. We aimed to develop a method for the assessment of functional capacity of gut microbiota butyrate synthesis
Nikola Daskova +8 more
doaj +1 more source
Proof-of-Principle Study Suggesting Potential Anti-Inflammatory Activity of Butyrate and Propionate in Periodontal Cells [PDF]
, 2022 Short-chain fatty acids (SCFAs) are potent immune modulators present in the gingival crevicular fluid. It is therefore likely that SCFAs exert a role in periodontal health and disease.
Panahipour, Layla +12 more
core +2 more sources