Results 31 to 40 of about 121,706 (306)

Butyrate-induced transcriptional changes in human colonic mucosa. [PDF]

PLoS ONE, 2009
Fermentation of dietary fiber in the colon results in the production of short chain fatty acids (mainly propionate, butyrate and acetate). Butyrate modulates a wide range of processes, but its mechanism of action is mostly unknown.
Steven A L W Vanhoutvin, Freddy J Troost, Henrike M Hamer, Patrick J Lindsey, Ger H Koek, Daisy M A E Jonkers, Andrea Kodde, Koen Venema, Robert J M Brummer   +8 more
doaj   +1 more source

Proteomic Analysis of Butyrate Effects and Loss of Butyrate Sensitivity in HT29 Colorectal Cancer Cells

, 2016
Butyrate, a fermentation product of the large bowel microflora, is potentially protective against the development of colorectal cancer. In vitro, butyrate has been shown to induce apoptosis and inhibit proliferation in numerous cancer cell lines ...
Richard Head (2217217), Leah J. Cosgrove (707313), Tanya Lewanowitsch (2016223), Trevor Lockett (707308), Kim Y. C. Fung (707301), Shaun R. McColl (307766), Peter Hoffmann (232366), Ilka Priebe (2388517), Steven T. Henderson (2388520)   +8 more
core   +3 more sources

A reverse transcription-quantitative polymerase chain reaction system for evaluating intestinal butyrate production by fecal bacteria

Applied and Environmental Microbiology
Intestinal butyrate is key in maintaining host health. As an indicator of butyrate production, the fecal butyrate concentration is used for assessing health status; however, it may not be a suitable marker as it only accounts for residual fecal butyrate ...
Mai Hane, Kazuhito Shimamoto, Ryo Matsui, Kensuke Shimizu, Miyuki Katto, Takashi Asahara, Yoshiyuki Shishido, Takashi Kurakawa   +7 more
doaj   +1 more source

An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases

Journal of Biological Engineering, 2021
Short-chain fatty acids, especially butyrate, play beneficial roles in sustaining gastrointestinal health. However, due to limitations associated with direct consumption of butyrate, there has been interest in using prodrugs of butyrate. Tributyrin (TB),
Dah Hyun Jung, Ji Hyun Yong, Wontae Hwang, Mi Young Yoon, Sang Sun Yoon   +4 more
doaj   +1 more source

Iron Modulates Butyrate Production by a Child Gut Microbiota In Vitro

mBio, 2015
The aim of this study was to investigate the effect of iron (Fe) availability on butyrate production in the complex bacterial ecosystem of the human gut.
Alexandra Dostal, Christophe Lacroix, Lea Bircher, Van Thanh Pham, Rainer Follador, Michael Bruce Zimmermann, Christophe Chassard   +6 more
doaj   +1 more source

Initial butyrate producers during infant gut microbiota development are endospore formers

, 2020
The acquisition of the infant gut microbiota is key to establishing a host-microbiota symbiosis. Microbially produced metabolites tightly interact with the immune system, and the fermentation-derived short-chain fatty acid butyrate is considered an ...
Roduit, Caroline; https://orcid.org/, Caroline Roduit, Appert, Olivia, Christophe Lacroix, Constancias, Florentin, Ferstl, Ruth, Remo Frei, Ruth Ferstl, Florentin Constancias, Roger Lauener, Olivia Appert, Cezmi Akdis, Vera Neuzil‐Bunesova, Neuzil-Bunesova, Vera, Alejandro Ramirez Garcia, Zhang, Jianbo, Clarissa Schwab, Schwab, Clarissa; https://orcid.org/, Frei, Remo, Jianbo Zhang, Lauener, Roger, Roduit, Caroline, Garcia, Alejandro Ramirez, Schwab, Clarissa, Akdis, Cezmi, Lacroix, Christophe   +25 more
core   +1 more source

Populations that previously encountered butyrate adapt more rapidly to consume it, once they again encounter butyrate.

, 2023
One day after initiation, cells from three LTSP experiments were filtered out of their LB media and re-inoculated into three flasks of M9 minimal media, either supplemented with 1 mM butyrate (A), or not (B).
Ifat Abramovich (15161398), Ruth Hershberg (23717), Bella Agranovich (15161401), Eyal Gottlieb (206953), Sophia Katz (484784), Alia Ghrayeb (6556199), Claudia Grajeda-Iglesias (7550201), Sabrin Hilau (13899783)   +7 more
core   +1 more source

Effects of different levels of dietary butyric acid on some growth performance, immunity and digestive enzymes activity of yellowfin seabream (Acanthopagrus latus Houttuyn, 1782) [PDF]

تغذیه آبزیان, 2020
This study was conducted to evaluate the effects of different dietary levels of butyric acid on growth performance, immunity and digestive enzyme activities in yellowfin seabream (Acanthopagrus latus) (8.59 ± 0.33 g) at the period of 60 days.
Gholamreza Badzohreh, Shirin Zarei, Reza Davoodi, Mahmoud Nafisi Bahabadi, Farzad Salehi, Vahid Morshedi, Ebrahim Sotoudeh   +6 more
doaj   +1 more source

Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia

BMC Pediatrics
Background Previous studies have found a reduction in butyrate-producing bacteria in the gut microbiota of infants with biliary atresia (BA). Butyrate is also an important inhibitor of histone deacetylase 2 (HDAC2).
Yilin Zhao, Xiaodan Xu, Shaowen Liu, Xueting Wang, Jiayinaxi Musha, Tengfei Li, Liang Ge, Yan Sun, Shujian Zhang, Li Zhao, Jianghua Zhan   +10 more
doaj   +1 more source

Butyrate reduces cellular magnesium absorption independently of metabolic regulation in Caco-2 human colon cells

Scientific Reports, 2022
Digestion of dietary fibers by gut bacteria has been shown to stimulate intestinal mineral absorption [e.g., calcium (Ca2+) and magnesium (Mg2+)]. Although it has been suggested that local pH and short-chain fatty acid (SCFA) concentrations determine ...
Lisanne M. M. Gommers, Pieter A. Leermakers, Jenny van der Wijst, Sara R. Roig, Anastasia Adella, Melissa A. E. van de Wal, René J. M. Bindels, Jeroen H. F. de Baaij, Joost G. J. Hoenderop   +8 more
doaj   +1 more source