Results 21 to 30 of about 133,313 (256)

A common mechanism links activities of butyrate in the colon [PDF]

, 2017
Two biological activities of butyrate in the colon (suppression of proliferation of colonic epithelial stem cells and inflammation) correlate with inhibition of histone deacetylases.
Michael J., Fink, Mohit, S. Verma, Stacy S., Ryu, George M., Whitesides, Hera, Vlamakis, Ramnik J., Xavier, Takahiro E., Ohara, Gabriel L, Salmon, Nadine, Fornelos, Thaddeus, S. Stappenbeck   +9 more
core   +2 more sources

Transcriptome characterization by RNA-seq unravels the mechanisms of butyrate-induced epigenomic regulation in bovine cells. [PDF]

PLoS ONE, 2012
Short-chain fatty acids (SCFAs), especially butyrate, affect cell differentiation, proliferation, and motility. Butyrate also induces cell cycle arrest and apoptosis through its inhibition of histone deacetylases (HDACs).
Sitao Wu, Robert W Li, Weizhong Li, Cong-Jun Li   +3 more
doaj   +1 more source

Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats

Journal of Pharmacological Sciences, 2021
Short chain fatty acids readily crosses the gut-blood and blood–brain barrier and acts centrally to influence neuronal signaling. We hypothesized that butyrate, a short-chain fatty acid produced by bacterial fermentation, in the central nervous system ...
Toshikatsu Okumura, Tsukasa Nozu, Masatomo Ishioh, Sho Igarashi, Shima Kumei, Masumi Ohhira   +5 more
doaj   +1 more source

The environment within: how gut microbiota may influence metabolism and body composition [PDF]

, 2010
Obesity, diabetes and consequently atherosclerotic vascular disease have become major health and public health issues worldwide. The increasing and staggering prevalence of obesity might not only be explained by nutritional habits or the reduction of ...
Vos, W.M., de, A. Vrieze, Hoekstra, J. B. L., E. G. Zoetendal, Zoetendal, E.G., F. Holleman, Vrieze, A., W. M. de Vos, J. B. L. Hoekstra, M. Nieuwdorp, Holleman, F., Zoetendal, E. G., Hoekstra, J.B., de Vos, W. M., de Vos, W.M., Nieuwdorp, M.   +15 more
core   +1 more source

Effects of different levels of dietary butyric acid on some growth performance, immunity and digestive enzymes activity of yellowfin seabream (Acanthopagrus latus Houttuyn, 1782) [PDF]

تغذیه آبزیان, 2020
This study was conducted to evaluate the effects of different dietary levels of butyric acid on growth performance, immunity and digestive enzyme activities in yellowfin seabream (Acanthopagrus latus) (8.59 ± 0.33 g) at the period of 60 days.
Gholamreza Badzohreh, Shirin Zarei, Reza Davoodi, Mahmoud Nafisi Bahabadi, Farzad Salehi, Vahid Morshedi, Ebrahim Sotoudeh   +6 more
doaj   +1 more source

Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts

, 2017
Background and Objective: Short-chain fatty acids, such as butyric acid and propionic acid, are metabolic by-products generated by periodontal microflora such as Porphyromonas gingivalis, and contribute to the pathogenesis of periodontitis.
Chang, M. -C.;Tsai, Y. -L.;Chen, Y. -W.;Chan, C. -P.;Huang, C. -F.;Lan, W. -C.;Lin, C. -C.;Lan, W. -H.;Jeng, J. -H., 蔡宜玲;藍萬烘;鄭景暉;陳漪紋   +1 more
core   +1 more source

Butyrate Supplementation at High Concentrations Alters Enteric Bacterial Communities and Reduces Intestinal Inflammation in Mice Infected with Citrobacter rodentium

mSphere, 2017
Butyrate is a short-chain fatty acid by-product of the microbial fermentation of dietary fermentable materials in the large intestine; it is the main energy source for enterocyte regeneration, modulates the enteric microbial community, and contributes to
Janelle A. Jiminez, Trina C. Uwiera, D. Wade Abbott, Richard R. E. Uwiera, G. Douglas Inglis   +4 more
doaj   +1 more source

A reverse transcription-quantitative polymerase chain reaction system for evaluating intestinal butyrate production by fecal bacteria

Applied and Environmental Microbiology
Intestinal butyrate is key in maintaining host health. As an indicator of butyrate production, the fecal butyrate concentration is used for assessing health status; however, it may not be a suitable marker as it only accounts for residual fecal butyrate ...
Mai Hane, Kazuhito Shimamoto, Ryo Matsui, Kensuke Shimizu, Miyuki Katto, Takashi Asahara, Yoshiyuki Shishido, Takashi Kurakawa   +7 more
doaj   +1 more source

Butyrate-induced transcriptional changes in human colonic mucosa. [PDF]

PLoS ONE, 2009
Fermentation of dietary fiber in the colon results in the production of short chain fatty acids (mainly propionate, butyrate and acetate). Butyrate modulates a wide range of processes, but its mechanism of action is mostly unknown.
Steven A L W Vanhoutvin, Freddy J Troost, Henrike M Hamer, Patrick J Lindsey, Ger H Koek, Daisy M A E Jonkers, Andrea Kodde, Koen Venema, Robert J M Brummer   +8 more
doaj   +1 more source

An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases

Journal of Biological Engineering, 2021
Short-chain fatty acids, especially butyrate, play beneficial roles in sustaining gastrointestinal health. However, due to limitations associated with direct consumption of butyrate, there has been interest in using prodrugs of butyrate. Tributyrin (TB),
Dah Hyun Jung, Ji Hyun Yong, Wontae Hwang, Mi Young Yoon, Sang Sun Yoon   +4 more
doaj   +1 more source