Results 21 to 30 of about 121,706 (306)

Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats

open access: yesJournal of Pharmacological Sciences, 2021
Short chain fatty acids readily crosses the gut-blood and blood–brain barrier and acts centrally to influence neuronal signaling. We hypothesized that butyrate, a short-chain fatty acid produced by bacterial fermentation, in the central nervous system ...
Toshikatsu Okumura   +5 more
doaj   +1 more source

A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]

open access: yes, 2006
ACKNOWLEDGMENTS: This work was supported by the Scottish Executive Environment and Rural Affairs Department. We would like to thank Sheila McCrae, Sylvie Duncan and Gillian Campbell for technical help and Wolfgang Buckel for helpful advice on the citrate
Charrier, Cedric   +9 more
core   +1 more source

Butyrate kinetics.

open access: yes, 2023
(A) Butyrate is produced during the first 24 hours of growth in LB and then consumed at days 18–22. Butyrate kinetics were monitored for 32 days by GCMS analyses on three independent LTSP populations, with LB media without inoculated bacteria serving as ...
Ifat Abramovich (15161398)   +7 more
core   +1 more source

Polyvinyl Butyrate Nanoparticles as Butyrate Donors for Colitis Treatment

open access: yesPolyvinyl Butyrate Nanoparticles as Butyrate Donors for Colitis Treatment
Butyrate has been attracting attention for the suppression of inflammatory bowel disease (IBD). However, clinical trials of butyrate for IBD treatment have resulted in controversial outcomes, likely owing to the adverse effect of butyrate on the intestinal epithelium that was observed at high butyrate concentrations.
ヨシカワ, タクマ   +23 more
openaire   +1 more source

Oral Supplementation With Butyrate Improves Myocardial Ischemia/Reperfusion Injury via a Gut-Brain Neural Circuit

open access: yesFrontiers in Cardiovascular Medicine, 2021
Objective: Butyrate, a short-chain fatty acid (SCFA) produced by the intestinal microbiota, plays a protective role in cardiovascular diseases (CVDs), but the mechanisms involved in this process remain unelucidated.
Zhiyao Yu   +59 more
doaj   +1 more source

Transcriptome characterization by RNA-seq unravels the mechanisms of butyrate-induced epigenomic regulation in bovine cells. [PDF]

open access: yesPLoS ONE, 2012
Short-chain fatty acids (SCFAs), especially butyrate, affect cell differentiation, proliferation, and motility. Butyrate also induces cell cycle arrest and apoptosis through its inhibition of histone deacetylases (HDACs).
Sitao Wu   +3 more
doaj   +1 more source

Analysis of microbiota-host communication mediated by butyrate in Atlantic salmon

open access: yesComputational and Structural Biotechnology Journal, 2023
Butyrate is a microbiota-produced metabolite, sensed by host short-chain fatty acid receptors FFAR2 (Gpr43), FFAR3 (Gpr41), HCAR2 (Gpr109A), and Histone deacetylase (HDAC) that promotes microbiota-host crosstalk.
Rodrigo A. Vargas   +15 more
doaj   +1 more source

Proof-of-Principle Study Suggesting Potential Anti-Inflammatory Activity of Butyrate and Propionate in Periodontal Cells [PDF]

open access: yes, 2022
Short-chain fatty acids (SCFAs) are potent immune modulators present in the gingival crevicular fluid. It is therefore likely that SCFAs exert a role in periodontal health and disease.
Panahipour, Layla   +12 more
core   +1 more source

Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts

open access: yes, 2017
Background and Objective: Short-chain fatty acids, such as butyric acid and propionic acid, are metabolic by-products generated by periodontal microflora such as Porphyromonas gingivalis, and contribute to the pathogenesis of periodontitis.
Chang, M. -C.;Tsai, Y. -L.;Chen, Y. -W.;Chan, C. -P.;Huang, C. -F.;Lan, W. -C.;Lin, C. -C.;Lan, W. -H.;Jeng, J. -H.   +1 more
core   +1 more source

Butyrate Supplementation at High Concentrations Alters Enteric Bacterial Communities and Reduces Intestinal Inflammation in Mice Infected with Citrobacter rodentium

open access: yesmSphere, 2017
Butyrate is a short-chain fatty acid by-product of the microbial fermentation of dietary fermentable materials in the large intestine; it is the main energy source for enterocyte regeneration, modulates the enteric microbial community, and contributes to
Janelle A. Jiminez   +4 more
doaj   +1 more source

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