Results 21 to 30 of about 104,308 (265)

Transcriptome characterization by RNA-seq unravels the mechanisms of butyrate-induced epigenomic regulation in bovine cells. [PDF]

PLoS ONE, 2012
Short-chain fatty acids (SCFAs), especially butyrate, affect cell differentiation, proliferation, and motility. Butyrate also induces cell cycle arrest and apoptosis through its inhibition of histone deacetylases (HDACs).
Sitao Wu, Robert W Li, Weizhong Li, Cong-Jun Li   +3 more
doaj   +1 more source

Butyrate Supplementation at High Concentrations Alters Enteric Bacterial Communities and Reduces Intestinal Inflammation in Mice Infected with Citrobacter rodentium

mSphere, 2017
Butyrate is a short-chain fatty acid by-product of the microbial fermentation of dietary fermentable materials in the large intestine; it is the main energy source for enterocyte regeneration, modulates the enteric microbial community, and contributes to
Janelle A. Jiminez, Trina C. Uwiera, D. Wade Abbott, Richard R. E. Uwiera, G. Douglas Inglis   +4 more
doaj   +1 more source

A reverse transcription-quantitative polymerase chain reaction system for evaluating intestinal butyrate production by fecal bacteria

Applied and Environmental Microbiology
Intestinal butyrate is key in maintaining host health. As an indicator of butyrate production, the fecal butyrate concentration is used for assessing health status; however, it may not be a suitable marker as it only accounts for residual fecal butyrate ...
Mai Hane, Kazuhito Shimamoto, Ryo Matsui, Kensuke Shimizu, Miyuki Katto, Takashi Asahara, Yoshiyuki Shishido, Takashi Kurakawa   +7 more
doaj   +1 more source

Butyrate-induced transcriptional changes in human colonic mucosa. [PDF]

PLoS ONE, 2009
Fermentation of dietary fiber in the colon results in the production of short chain fatty acids (mainly propionate, butyrate and acetate). Butyrate modulates a wide range of processes, but its mechanism of action is mostly unknown.
Steven A L W Vanhoutvin, Freddy J Troost, Henrike M Hamer, Patrick J Lindsey, Ger H Koek, Daisy M A E Jonkers, Andrea Kodde, Koen Venema, Robert J M Brummer   +8 more
doaj   +1 more source

An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases

Journal of Biological Engineering, 2021
Short-chain fatty acids, especially butyrate, play beneficial roles in sustaining gastrointestinal health. However, due to limitations associated with direct consumption of butyrate, there has been interest in using prodrugs of butyrate. Tributyrin (TB),
Dah Hyun Jung, Ji Hyun Yong, Wontae Hwang, Mi Young Yoon, Sang Sun Yoon   +4 more
doaj   +1 more source

Effects of different levels of dietary butyric acid on some growth performance, immunity and digestive enzymes activity of yellowfin seabream (Acanthopagrus latus Houttuyn, 1782) [PDF]

تغذیه آبزیان, 2020
This study was conducted to evaluate the effects of different dietary levels of butyric acid on growth performance, immunity and digestive enzyme activities in yellowfin seabream (Acanthopagrus latus) (8.59 ± 0.33 g) at the period of 60 days.
Gholamreza Badzohreh, Shirin Zarei, Reza Davoodi, Mahmoud Nafisi Bahabadi, Farzad Salehi, Vahid Morshedi, Ebrahim Sotoudeh   +6 more
doaj   +1 more source

Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia

BMC Pediatrics
Background Previous studies have found a reduction in butyrate-producing bacteria in the gut microbiota of infants with biliary atresia (BA). Butyrate is also an important inhibitor of histone deacetylase 2 (HDAC2).
Yilin Zhao, Xiaodan Xu, Shaowen Liu, Xueting Wang, Jiayinaxi Musha, Tengfei Li, Liang Ge, Yan Sun, Shujian Zhang, Li Zhao, Jianghua Zhan   +10 more
doaj   +1 more source

Iron Modulates Butyrate Production by a Child Gut Microbiota In Vitro

mBio, 2015
The aim of this study was to investigate the effect of iron (Fe) availability on butyrate production in the complex bacterial ecosystem of the human gut.
Alexandra Dostal, Christophe Lacroix, Lea Bircher, Van Thanh Pham, Rainer Follador, Michael Bruce Zimmermann, Christophe Chassard   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Butyrate reduces cellular magnesium absorption independently of metabolic regulation in Caco-2 human colon cells

Scientific Reports, 2022
Digestion of dietary fibers by gut bacteria has been shown to stimulate intestinal mineral absorption [e.g., calcium (Ca2+) and magnesium (Mg2+)]. Although it has been suggested that local pH and short-chain fatty acid (SCFA) concentrations determine ...
Lisanne M. M. Gommers, Pieter A. Leermakers, Jenny van der Wijst, Sara R. Roig, Anastasia Adella, Melissa A. E. van de Wal, René J. M. Bindels, Jeroen H. F. de Baaij, Joost G. J. Hoenderop   +8 more
doaj   +1 more source