Results 21 to 30 of about 3,215 (244)
Acta Cirúrgica Brasileira, 2010 PURPOSE: To evaluate the preventive effect of sodium butyrate in the appearance of aberrant crypt foci (ACF) in rats after induction with the carcinogen 1,2-dimethylhydrazine (DMH).
Fernanda Guimarães Drummond e Silva +6 more
doaj +1 more source
Management of ß-thalassemia – Consensus and controversies!
Pediatric Hematology Oncology Journal, 2017 The mainstay of treatment of ß-Thalassemia major includes life-long regular packed red cell transfusions and iron chelation. With advances in understanding the molecular biology and its implications in the patients, newer modalities are now being ...
Mamta V. Manglani, Pranoti S. Kini
doaj +1 more source
Microbial synthesis of a branched-chain ester platform from organic waste carboxylates
Metabolic Engineering Communications, 2016 Processing of lignocellulosic biomass or organic wastes produces a plethora of chemicals such as short, linear carboxylic acids, known as carboxylates, derived from anaerobic digestion.
Donovan S. Layton, Cong T. Trinh
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Discover Applied SciencesThis study set out to compare the addition of butyrate (sodium-calcium butyrates), herbal extract (Macleaya cordata), and yeast (Saccharomyces cerevisiae) feed additives on the broiler’s growth performance, serum parameters, organ weight, and ileum ...
Muhittin Zengin +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Agriculture and Food ResearchThis study employed metabolomics approaches to systematically elucidate the key pathways and regulatory mechanisms by which sodium butyrate modulated fatty acid metabolism in ruminants, thereby addressing the knowledge gap regarding its roles in fatty ...
Yue Zhang +7 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Glutamine alone or combined with short-chain fatty acids fails to enhance gut adaptation after massive enterectomy in rats Glutamina pura ou combinada com ácidos graxos de cadeia curta não melhora a capacidade adaptativa do intestino após enterectomia extensa em ratos
Acta Cirúrgica Brasileira, 2006 PURPOSE: To investigate the effect of oral glutamine alone or combined with short chain fatty acids (SCFA) in the intestinal adaptation of rats submitted to an massive enterectomy.
José de Souza Neves +6 more
doaj +1 more source